scholarly journals Monitoring and Reporting of Adverse Drug Reactions Due to Cardiovascular Drugs in Patients Admitted to a Secondary Care Hospital in Northern Emirate- a Prospective Surveillance Study

2018 ◽  
Vol 11 (2) ◽  
pp. 71-78 ◽  
Author(s):  
Tarun Wadhwa ◽  
Samar Gamal El Sheikh ◽  
Padma G.M. Rao
Keyword(s):  
Adverse Drug Reactions ◽  
Secondary Care ◽  
Cardiovascular Drugs ◽  
Surveillance Study ◽  
Care Hospital ◽  
Drug Reactions ◽  
Prospective Surveillance

scholarly journals An assessment of pattern of adverse drug reactions of cardiovascular drugs in a tertiary care institute

2018 ◽  
Vol 7 (2) ◽  
pp. 273 ◽  
Author(s):  
Smita Y. Wankhede ◽  
Milind L. Pardeshi ◽  
Vishal V. Ghorpade ◽  
Balasaheb B. Ghongane
Keyword(s):  
Adverse Drug Reactions ◽  
Demographic Data ◽  
Tertiary Care ◽  
Cardiovascular Drugs ◽  
Care Hospital ◽  
Drug Reactions ◽  
Microsoft Excel ◽  
Entire Study ◽  
Cardiovascular Medications ◽  
One Year

Background: Cardiovascular disease is very prevalent in India. So, use of cardiovascular drugs is also more. So, it is very important to keep watch on adverse drug reactions. Aim of this study was to assess the pattern of adverse drug reactions (ADRs) reported with cardiovascular drugs in a tertiary care institute.Methods: The study was carried out in medicine department of a tertiary care hospital over a period of one year. Each ADR was analysed for demographic data, causality, relationship between frequency of ADRs and the number of drugs used etc. In statistical analysis Microsoft excel 2013, SPSS software was used.Results: A total of 136 patients, 58 (43%) men and 78 (57%) women, using cardiovascular medications reported ADRs during the entire study period. Total 168 ADRs were reported out of which, Amlodipine (causing headache and edema feet) was the most common drug with 51 (30.3%) ADR’s followed by Enalapril, Aspirin and Isosorbide Dinitrate with 37 (22%), 24 (14.2%), 23 (13.6%) ADRs respectively. Most common ADR was headache (due to amlodipine and Isosorbide di nitrate) affecting 38 (22.62%) cases followed by dry cough 37 (22.02%) cases, edema feet 36 (21.43%), gastritis 24 (14.29%) and 10 (5.95%) of nausea.Conclusions: Monitoring ADRs in patients using cardiovascular drugs is a matter of importance since this class of medicines are mostly used as multidrug therapy and always prone for ADRs.

scholarly journals Intensive Monitoring of Adverse Drug Reactions to Antiepileptic Drugs in Neurology Department of a Secondary Care Hospital in U.A.E

2019 ◽  
Vol 11 (2) ◽  
pp. 192-196
Author(s):  
Hanin Jalal Alkhalil ◽  
Sathvik Belagodu Sridhar ◽  
Syed Arman Rabbani ◽  
Ammar Al Omar
Keyword(s):  
Antiepileptic Drugs ◽  
Adverse Drug Reactions ◽  
Secondary Care ◽  
Care Hospital ◽  
Drug Reactions ◽  
Intensive Monitoring

scholarly journals Adverse Drug Reactions Of Cardiovascular Drugs In Intensive Cardiac Care Unit In A Tertiary Care Hospital: A Prospective Study

2019 ◽  
Vol 12 (3) ◽  
pp. 1079-1083
Author(s):  
Hemanthkumar Shanmugam ◽  
Nithya Panneerselvam ◽  
Arul Amutha Lawrence
Keyword(s):  
Cardiovascular Diseases ◽  
Adverse Drug Reactions ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cardiovascular Drugs ◽  
Cardiac Care ◽  
Care Hospital ◽  
Drug Reactions ◽  
Multiple Drugs ◽  
Cardiac Care Unit

Cardiovascular diseases are prevalent in developing countries like India. Patients with cardiovascular diseases are prescribed multiple drugs, hence polypharmacy may attribute to higher incidence of adverse drug reactions in these patients. To monitor and to analyze the pattern of occurrence of adverse drug reactions reported with cardiovascular drugs in intensive cardiac care unit of a tertiary care hospital, Chennai. This was a prospective surveillance study carried out for a period of 6 months. Analysis of various adverse drug reactions reported were done using various assessment scales. Descriptive statistics was used and values were expressed in numbers and percentage. During the study period, 282 adverse reactions were reported from 389 patientsat includes 232 males and 157 females. The average age of the patients included in this study was 58.1± 16.8 years . The most common ADRs observed were electrolyte imbalance (14.89%), headache (13.12%) and gastritis (12.41%). Assessment using WHO Causality assessment scale revealed 60.28% were possible, 18.43% probable, 12.76% certain and 8.51% unlikely. According to Schumock and Thornton scale 65.9% of ADRs were preventable and 34% non preventable. Analysis with Hartwig and Seigel’s scale 62.05% of ADRs were moderate in severity, 27.95% mild and 10.99% severe. Drugs attributing to highest ADRs were Digoxin and Furosemide. The common ADRs due to cardiovascular drugs can be reduced by improving the prescription pattern. Intense monitoring and reporting of ADRs could help in minimizing the preventable ADRs, among the health care professionals.

scholarly journals Prospective monitoring of cutaneous adverse drug reactions in a secondary care hospital, UAE

2019 ◽  
Vol 5 (2) ◽  
pp. 231
Author(s):  
Fatma Al Mulla ◽  
Sathvik B. Sridhar ◽  
Ghada Abu Al Hassan ◽  
Atiqulla Sharif
Keyword(s):  
Adverse Drug Reactions ◽  
Secondary Care ◽  
Adverse Reactions ◽  
World Health ◽  
Care Hospital ◽  
Drug Reactions ◽  
Case Files ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Health Organization

<p class="abstract"><strong>Background:</strong> Adverse drug reactions (ADRs) are one of the most important causes of morbidity, hospitalization, increased healthcare cost and even mortality. Cutaneous adverse reactions are most commonly documented for drugs. The aim of the study was to monitor the incidence and nature of cutaneous adverse drug reactions (CADRs) in the dermatology outpatients and identify the causative drugs.</p><p class="abstract"><strong>Methods:</strong> A prospective observational study was conducted at the dermatology outpatient department of a secondary care hospital, UAE. All the patients attending dermatology outpatient and satisfying the inclusion criteria were monitored for ADRs. The required data were collected from the patients, their case files, and caretakers and entered in a suitably designed ADR reporting and documentation form. The causality, severity, and preventability of cutaneous ADRs were assessed using Naranjo, WHO, Hartwig and modified Schumock and Thornton scale.<strong></strong></p><p class="abstract"><strong>Results:</strong> The prevalence of cutaneous ADRs was found to be 2.6%. Majority (43.4%) of the cutaneous ADRs were caused by nonsteroidal anti-inflammatory drugs. Majority (56.5%) of the study population reported itching as the most common cutaneous ADR. Also, 60.8% of the reported ADRs were “probable” in nature according to World Health Organization scale, whereas 56.5% reports were “probable” according to Naranjo’s algorithm. Majority (97%) of the ADRs were not preventable.</p><p class="abstract"><strong>Conclusions:</strong> Nonsteroidal anti-inflammatory drugs were the common causes of cutaneous ADRs in the study. Majority of the adverse reactions were mild in nature. The type and nature of cutaneous adverse drug reaction profile documented in this study is almost similar in many ways to other ADRs monitoring studies conducted in dermatology outpatient clinics.</p>

Adverse Drug Reactions: Trends in a Tertiary Care Hospital

2013 ◽  
Vol 7 (5) ◽  
pp. 384-388
Author(s):  
Harmeet S. Rehan ◽  
Deepti Chopra ◽  
Ravinder K. Sah ◽  
Ritu Mishra
Keyword(s):  
Adverse Drug Reactions ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Drug Reactions
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