scholarly journals Development of Rapid and Validated RP-HPLC Method for Concurrent Quantification of Rosuvastatin and Aspirin form Solid Dosage Form

2018 ◽  
Vol 52 (1) ◽  
pp. 151-158
Author(s):  
Mahesh Attimarad ◽  
Ahmed Alkadham ◽  
Mohammed Hashem Almosawi ◽  
Katharigatta Narayanaswamy Venugopala
Keyword(s):  
Dosage Form ◽  
Hplc Method ◽  
Solid Dosage Form ◽  
Solid Dosage ◽  
Rp Hplc

scholarly journals Stability Indicating RP-HPLC Method for Determination of Tolterodine in Solid Dosage Form

2009 ◽  
Vol 8 (4) ◽  
pp. 184
Author(s):  
S. G. Vasantharaju ◽  
Mishra Akanksha ◽  
Arumugam Karthik ◽  
Musmade P. Prashant ◽  
Udupa Nayanabhirama ◽  
...  
Keyword(s):  
Dosage Form ◽  
Hplc Method ◽  
Stability Indicating ◽  
Solid Dosage Form ◽  
Solid Dosage ◽  
Rp Hplc

scholarly journals Comparison of UV-spectrophotometric and RP-HPLC methods for estimation of deflazacort in solid dosage form

2020 ◽  
Author(s):  
Puranik Manisha ◽  
Shambharkar Samta ◽  
Nimbalkar Shantanu ◽  
Mahapatra Debarshi Kar
Keyword(s):  
Dosage Form ◽  
Solid Dosage Form ◽  
Solid Dosage ◽  
Rp Hplc

scholarly journals Simultanious Determination of Related Organic Impurities of Ibuprofen and Paracetamol in Combination Solid Dosage Form by Rp-hplc With Qbd Approach

2017 ◽  
Vol 33 (3) ◽  
pp. 1461-1468 ◽  
Author(s):  
Palakurthi Ashok Kumar ◽  
Dongala Thirupathi ◽  
Y Ravindra Kumar ◽  
Anireddy Jayashree
Keyword(s):  
Dosage Form ◽  
Solid Dosage Form ◽  
Solid Dosage ◽  
Rp Hplc ◽  
Organic Impurities

scholarly journals Development and Validation of RP-HPLC Method for the Simultaneous Determination of Rabeprazole Sodium and Itopride Hydrochloride in Solid Dosage Form

2010 ◽  
Vol 7 (3) ◽  
pp. 947-952 ◽  
Author(s):  
Rajesh Sharma ◽  
Ganesh Prasad Mishra ◽  
Subhash Chandra Chaturvedi
Keyword(s):  
Simultaneous Determination ◽  
High Performance ◽  
Dosage Form ◽  
High Performance Liquid Chromatographic ◽  
Hplc Method ◽  
Solid Dosage Form ◽  
Solid Dosage ◽  
Rabeprazole Sodium ◽  
Itopride Hydrochloride

A simple, sensitive, precise, accurate, rapid and reproducible reverse phase high performance liquid chromatographic procedure is developed for simultaneous determination of rabeprazole sodium and itopride hydrochloride in solid dosage form. The mobile phase used was a combination of acetonitrile: buffer (35:65 v/v) and the pH was adjusted to 7.0 ± 0.1 by addition of triethylamine. The detection of the capsule dosage form was carried out at 266 nm and a flow rate employed was 1 mL/min. Linearity was obtained in the concentration range of 2 to 16 μg/mL of rabeprazole sodium and 5 to 55 μg/mL of itopride hydrochloride with a correlation coefficient of 0.9992 and 0.9996 respectively. The results of the analysis were validated statistically and recovery studies confirmed the accuracy of the proposed method.

scholarly journals Comparison of the Robustness of Spectrophotometric Method and High-Performance Liquid Chromatographic Method for the Determination of Pioglitazone in Solid Dosage Form

2021 ◽  
pp. 37-45
Author(s):  
Sara Zahid ◽  
Fatima Zahid ◽  
Asma Ahmed ◽  
Waqas Safir
Keyword(s):  
Spectrophotometric Method ◽  
Analytical Method ◽  
High Performance ◽  
Dosage Form ◽  
Raw Materials ◽  
High Performance Liquid Chromatographic ◽  
Hplc Method ◽  
The Body ◽  
Solid Dosage Form ◽  
Solid Dosage

Pioglitazone is a drug that reduces the amount of glucose (sugar) in the blood. It is included in the class of anti-diabetic drugs called “thiazolidinedione” that are used in the treatment of type II diabetes. It attaches to the peroxisomes proliferated- activated receptor gamma (PPARϒ) on tissues throughout the body and causes the cells to become more sensitive to insulin. As a result, more glucose is removed from the blood.The aim of the study is more precisely to find out the better analytical method for the quantitative measurement of the content of pioglitazone in commercially available drugs using two analytical methods i-e Spectrophotometric method and HPLC method.The analytical method for the pioglitazone hydrochloride was developed by HPLC, and then validated the method according to compendial requirements. Pioglitazone in various Dowglit and Gliden tablets was determined by this developed methodPrecision, Accuracy and stability of Pioglitazone was checked which came out to be100.40% and 100.19% respectively. The analysis of pioglitazone hydrochloride in solid dosage form using the HPLC method shows the results are more sensitive, accurate, validated and economical and can be easily applied to raw materials and finished goods compared to the Spectrophotometer method.

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