Evaluation of prognostic factors affecting root coverage in patients before planned orthodontic treatment

2018 ◽  
Vol 14 (4) ◽  
pp. 257-269
Author(s):  
Bartłomiej Górski ◽  
Renata Górska

During orthodontic dental arch expansion, especially in cases of teeth with gingival recessions, further loss of soft tissues and progression of recession might be observed. <b>Aim.</b> The aim of this study was to evaluate determinants of root coverage, increase in the width of keratinised tissue and gingival thickness after soft tissue augmentation procedures in patients before planned orthodontic treatment. <b>Material and methods.</b> 16 patients with the mean age of 28.18 (±6.58) years with 122 type I and II gingival recessions were enrolled in the study. Total, 32 soft tissue augmentation procedures with a coronally advanced flap (CAF) and tunnel technique (TUN) together with a connective tissue graft (CTG) were performed. The clinical and aesthetic parameters were assessed at baseline and 6 months postoperatively. <b>Results.</b> CAF was performed more often in upper teeth and type I gingival recession, in contrast to TUN. The mean percentage root coverage on CAF sides was 98.48%, while on TUN sides it was 81.71%. Complete root coverage was achieved in 87.3% and 61.2% of gingival recessions, respectively. A multivariate linear regression showed that the amount of root coverage was significantly affected by baseline recession height (GR), recession type, type and position of a tooth and surgical modality. The increase in the width of keratinised tissue (WKT) was related to the baseline width of keratinised tissue, type and position of a tooth, whereas the increase in gingival thickness (GT) was associated with baseline gingival thickness, tooth position and gender. Best aesthetics was observed on the TUN sides. <b>Conclusions.</b> Baseline characteristics of a surgical site (GR, WKT, GT), recession type, position and type of a tooth, and treatment modality may be helpful in the prognosis of recession coverage, increase in the width of keratinised tissue and gingival thickness in orthodontic patients.

Author(s):  
Su Yeon Lee ◽  
Yongdoo Park ◽  
Soon Jung Hwang

Abstract Background Hyaluronic acid (HA) has been applied as a primary biomaterial for temporary soft tissue augmentation and as a carrier for cells and the delivery of growth factors to promote tissue regeneration. Although HA derivatives are the most versatile soft tissue fillers on the market, they are resorbed early, within 3 to 12 months. To overcome their short duration, they can be combined with cells or growth factors. The purpose of this study was to investigate the stimulating effects of human fibroblasts and basic fibroblast growth factors (bFGF) on collagen synthesis during soft tissue augmentation by HA hydrogels and to compare these with the effects of a commercial HA derivative (Restylane®). Methods The hydrogel group included four conditions. The first condition consisted of hydrogel (H) alone as a negative control, and the other three conditions were bFGF-containing hydrogel (HB), human fibroblast-containing hydrogel (HF), and human fibroblast/bFGF-containing hydrogel (HBF). In the Restylane® group (HGF), the hydrogel was replaced with Restylane® (R, RB, RF, RBF). The gels were implanted subdermally into the back of each nude mouse at four separate sites. Twelve nude mice were used for the hydrogel (n = 6) and Restylane® groups (n = 6). The specimens were harvested 8 weeks after implantation and assessed histomorphometrically, and collagen synthesis was evaluated by RT-PCR. Results The hydrogel group showed good biocompatibility with the surrounding tissues and stimulated the formation of a fibrous matrix. HBF and HF showed significantly higher soft tissue synthesis compared to H (p < 0.05), and human collagen type I was well expressed in HB, HF, and HBF; HBF showed the strongest expression. The Restylane® filler was surrounded by a fibrous capsule without any soft tissue infiltration from the neighboring tissue, and collagen synthesis within the Restylane® filler could not be observed, even though no inflammatory reactions were observed. Conclusion This study revealed that HA-based hydrogel alone or hydrogel combined with fibroblasts and/or bFGF can be effectively used for soft tissue augmentation.


QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
N S Abdelfattah ◽  
R M Elhusseiny ◽  
A A Mahmoud

Abstract Background There is an increasing demand for aesthetic correction of deep NLFs. Dermal fillers are one of the nonsurgical options for soft tissue augmentation, plasma filler is a recent technique tried in soft tissue augmentation. This procedure could be performed on an outpatient basis at a moderate cost, without any rejection reactions. Objective The presented study aimed to confirm the efficacy and safety of autologous plasma filler in treating nasolabial fold wrinkles. Subjects and Methods The present study included 40 females attended the Dermatology outpatient clinic of Ain Shams University Hospitals from March 2017 to November 2017. The age of patients ranged from 20 to 60 years old, with the mean age of 38.60 years old ± 11.48 SD. Results The overall success of our study was defined according to clinical improvement of NLFs subjectively by patients' satisfaction score which showed that 42.5% of patients rated their improvement as excellent, 35% as good and 22.5% as poor. The mean of WSRS decreased significantly from (3.20 ± 0.96) before treatment to (1.50 ±0.630) after 4 weeks of the treatment session. Furthermore, the mean value of GAIS scores 2 weeks after treatment session was (4.47 + 0.730) then become (4.03±0.964) 4 weeks after the treatment session. Conclusion In conclusion, Treatment with plasma filler injection resulted in significant improvement of NLFs with minimal complications.


2019 ◽  
Vol 04 (01) ◽  
pp. e1-e8 ◽  
Author(s):  
Masayuki Okochi ◽  
Hiromi Okochi ◽  
Takao Sakaba ◽  
Kazuki Ueda

Background We performed soft tissue augmentation using free flap and secondary cranioplasty combined with soft tissue augmentation for cases with artificial or autologous skull exposure after neurosurgery. We evaluated operative result and the relationship between the cause of infection and the infected site. Methods Twenty-four patients were included. Data included age, sex, indications for neurosurgery, causes of infection, infection sites, medical comorbidities, time between last neurosurgery and reconstruction, types of reconstruction, and types of secondary cranioplasty. Results The causes of neurosurgery were subarachnoid hemorrhage (n = 9), trauma (n = 5), brain tumor (n = 5), brain hemorrhage (n = 3), and meningioma (n = 3). The mean size of infected bone was 67.3 cm2. The mean duration between last neurosurgery and reconstruction was 5.2 years. Types of infected bone were artificial bone (n = 19) and autologous skull (n = 6). The soft tissue augmentation was performed using latissimus dorsi myocutaneous flap (n = 14) and anterolateral thigh flap (n = 10). The infection sites were the frontal (n = 13), temporal (n = 4), parietal (n = 4), and occipital regions (n = 4). Bone defects included the frontal sinus in all patients who had infections in the frontal region. The patients who had infections in non-frontal region received multiple surgeries (n = 7). Nine patients received secondary cranioplasty using custom-made hydroxyapatite block. Conclusion To achieve good results during soft tissue augmentation, the cause of infection should be eliminated.


2015 ◽  
Vol 3 (2) ◽  
pp. 53-58
Author(s):  
Nima Ebrahimi ◽  
Julio E Obando ◽  
Michael L. Schmerman ◽  
Saba M. Khan ◽  
Nadia I. Kawar

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