Ischemic preconditioning and N-acetylcysteine in a rat model of skeletal muscle ischemia-reperfusion: does antioxidant therapy have an impact on ischemic preconditioning?

2012 ◽  
Vol 20 (4) ◽  
pp. 862-868 ◽  
Author(s):  
Uğur Gürcün
Keyword(s):  
Skeletal Muscle ◽  
Ischemic Preconditioning ◽  
Rat Model ◽  
Ischemia Reperfusion ◽  
Antioxidant Therapy ◽  
Muscle Ischemia

Effects of ischemic preconditioning protocols on skeletal muscle ischemia–reperfusion injury

2015 ◽  
Vol 193 (2) ◽  
pp. 942-952 ◽  
Author(s):  
Emre A. Kocman ◽  
Orhan Ozatik ◽  
Aykut Sahin ◽  
Turkan Guney ◽  
Aydan A. Kose ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Reperfusion Injury ◽  
Ischemic Preconditioning ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Muscle Ischemia

Neutrophils as mediators of human skeletal muscle ischemia-reperfusion syndrome

1992 ◽  
Vol 23 (6) ◽  
pp. 627-634 ◽  
Author(s):  
Lucia Formigli ◽  
Lola Domenici Lombardo ◽  
Chiara Adembri ◽  
Sandra Brunelleschi ◽  
Enrico Ferrari ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Human Skeletal Muscle ◽  
Ischemia Reperfusion ◽  
Muscle Ischemia

Sequential ischemia/reperfusion results in contralateral skeletal muscle salvage

1996 ◽  
Vol 270 (4) ◽  
pp. H1407-H1413 ◽  
Author(s):  
S. K. Liauw ◽  
B. B. Rubin ◽  
T. F. Lindsay ◽  
A. D. Romaschin ◽  
P. M. Walker
Keyword(s):  
Skeletal Muscle ◽  
Preliminary Analysis ◽  
Adenine Nucleotides ◽  
Ischemia Reperfusion ◽  
Gracilis Muscle ◽  
Muscle Group ◽  
Muscle Ischemia ◽  
Muscle Necrosis ◽  
Shock Proteins

Sequential ischemia/reperfusion in a paired canine gracilis muscle model resulted in significant muscle salvage. In this model, one randomly chosen gracilis muscle was subjected to 5 h of ischemia followed by 48 h of in vivo reperfusion. The contralateral (second) muscle was then made ischemic and reperfused using the same protocol. Muscle necrosis was determined at the end of 48 h of reperfusion. A mean 60% reduction in muscle necrosis was observed in the second group of muscles. Analysis of tissue adenine nucleotides indicated that significant sparing of ATP utilization occurred in the second muscle group during ischemia. Preliminary analysis of tissue heat shock proteins (HSP) showed that the second group of muscles had a different pattern of HSP expression before the onset of ischemia. The results suggest that reduced ATP utilization and altered HSP expression in the second muscle play a role in the tissue salvage observed in this sequential muscle ischemia model.

scholarly journals Attenuation of skeletal muscle ischemia/reperfusion injury by inhibition of tumor necrosis factor

1999 ◽  
Vol 29 (2) ◽  
pp. 370-376 ◽  
Author(s):  
Gregory C. Gaines ◽  
M.Burress Welborn III ◽  
Lyle L. Moldawer ◽  
Thomas S. Huber ◽  
Timothy R.S. Harward ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Tumor Necrosis Factor ◽  
Reperfusion Injury ◽  
Tumor Necrosis ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Muscle Ischemia ◽  
Necrosis Factor
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