scholarly journals Analysis of Adverse Events Associated with the Anti-Allergic Agents Rx-to-OTC-Switched Using Data Mining of the Japanese Adverse Drug Event Report (JADER) Database

2015 ◽  
Vol 41 (9) ◽  
pp. 667-675 ◽  
Author(s):  
Yoshihiro Noguchi ◽  
Hiroki Esaki ◽  
Shoko Asano ◽  
Takafumi Yokoi ◽  
Kazumasa Usui ◽  
...  
Keyword(s):  
Data Mining ◽  
Adverse Events ◽  
Adverse Drug Event ◽  
Drug Event ◽  
Event Report ◽  
Using Data

scholarly journals Evaluation of the Association between the Use of Oral Anti-hyperglycemic Agents and Hypoglycemia in Japan by Data Mining of the Japanese Adverse Drug Event Report (JADER) Database

2014 ◽  
Vol 134 (2) ◽  
pp. 299-304 ◽  
Author(s):  
Ryogo Umetsu ◽  
Yuri Nishibata ◽  
Junko Abe ◽  
Yukiya Suzuki ◽  
Hideaki Hara ◽  
...  
Keyword(s):  
Data Mining ◽  
Adverse Drug Event ◽  
Drug Event ◽  
Event Report

scholarly journals Adverse Event Trends Associated with Over-the-counter Combination Cold Remedy: Data Mining of the Japanese Adverse Drug Event Report Database

2018 ◽  
Vol 138 (1) ◽  
pp. 123-134 ◽  
Author(s):  
Sayaka Sasaoka ◽  
Haruna Hatahira ◽  
Shiori Hasegawa ◽  
Yumi Motooka ◽  
Akiho Fukuda ◽  
...  
Keyword(s):  
Data Mining ◽  
Adverse Event ◽  
Adverse Drug Event ◽  
Drug Event ◽  
Event Report ◽  
Over The Counter ◽  
Cold Remedy

scholarly journals Adverse Event Trends Associated with OTC Analgesic and Antipyretic Drug: Data Mining of the Japanese Adverse Drug Event Report Database

2017 ◽  
Vol 137 (10) ◽  
pp. 1301-1311 ◽  
Author(s):  
Shiori Hasegawa ◽  
Haruna Hatahira ◽  
Misa Naganuma ◽  
Akari Shimauchi ◽  
Sayaka Sasaoka ◽  
...  
Keyword(s):  
Data Mining ◽  
Adverse Event ◽  
Adverse Drug Event ◽  
Drug Event ◽  
Event Report

scholarly journals Analysis of patients with hypomagnesemia using the Japanese Adverse Drug Event Report database (JADER)

2018 ◽  
Vol 21 ◽  
pp. 46-53 ◽  
Author(s):  
Hiroyuki Tanaka ◽  
Yuka Yoshiba ◽  
Tomoko Watanabe ◽  
Mitsutoshi Satoh ◽  
Toshihiro Ishii
Keyword(s):  
Adverse Events ◽  
Adverse Drug Event ◽  
Antitumor Agent ◽  
Drug Event ◽  
Reporting Odds Ratio ◽  
Event Report ◽  
Drug Involvement ◽  
Large Peak ◽  
Egfr Antibody ◽  
Electrolyte Abnormalities

Summary – Purpose. In order to clarify the occurrence of hypomagnesemia in Japan, we conducted a database search and analysis using the Japanese Adverse Drug Event Report database (JADER). Methods. Among the cases recorded in JADER between April 2004 and December 2015, we targeted “hypomagnesemia” and analyzed the patients’ backgrounds, drug involvement, other adverse events reported with hypomagnesemia, the time of hypomagnesemia onset, outcomes, and year when reported. For drugs with three or more reports, the signal index was calculated using the Reporting Odds Ratio (ROR) method. In addition, the association between hypomagnesemia onset and other adverse events was investigated using association analysis. Results. The total number of reported hypomagnesemia cases was 201. Males accounted for 62.7%, and patients in their sixties formed a large peak. Three or more cases were reported for 23 causative drugs, among which anti-EGFR antibody, calcineurin inhibitor, platinum antitumor agent and proton pump inhibitor accounted for the majority. ROR analysis detected signals for 18 drugs, and an association was found between hypomagnesemia and other electrolyte abnormalities for those drugs. The median time until onset of hypomagnesemia was classified into three patterns: around 10 days, around 30 days, and longer. Analysis of the report year revealed an increasing tendency in recent years, although increases/decreases were evident depending on fiscal years. Conclusion. Our survey was able to reveal the factors associated with the occurrence of hypomagnesemia.

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