Electrochemical Determination of Albendazole at Glassy Carbon Electrode
Abstract In this article, the electrochemical behavior on a glassy carbon electrode (GCE) was investigated and the electrochemical parameters of albendazole (ALB) were calculated. ALB effectively accumulated on the GCE surface and caused a pair of redox peaks at around 1.095 V and 1.028 V and an oxidation peak at 0.844 V (versus saturated calomel electrode) in 0.2 M phosphate buffer solution (pH 3.0). Under optimized conditions, the anodic peak current was linear to the ALB concentration the range of 1.5 × 10−7 M to 4.0 × 10−5 M. The regression equation was: Ipa (10−6 A) = 0.79 [ALB] (μM) + 0.84 (R2 = 0.982). The detection limit 6.08 × 10−8 M was obtained. The proposed method was successfully used to determine ALB content in tablet samples, with satisfactory results.