scholarly journals Clinical risk factors of ICU & fatal COVID-19 cases in Brazil

2020 ◽  
Author(s):  
Juliana Barcellos Mattos ◽  
Eraylson Silva ◽  
Paulo Mattos Neto ◽  
Renato Vimieiro

The Coronavirus disease 2019 (COVID-19) was first detected in China in December 2019. In a few months, the disease got pandemic proportions, overloading health systems all around the world. Risk factors related to the progression and outcome of the disease are still unclear. Moreover, clinical aspects of patients can differ between societies, and other demographic elements may impact survival responses. A better characterisation of local manifestation of COVID-19 is crucial to a better general understanding of the disease, and thus to improve treatment decisions and health systems’ management. In this article, we performed an initial analysis of clinical factors related to admission in ICU or death of SARS-CoV-2 confirmed Brazilian patients, based on 1,138,690 medical records from the Brazilian government. To our knowledge, this study is the first to assess clinical risk factors for disease progression in Brazil. We provide a concise data set of medical registers related to COVID-19 in the whole Brazilian territory, and we describe the baseline comorbidities and symptoms observed in the data collection. Then, we assess the correlation between the manifestation of symptoms/comorbidities and the patients’ survival response through Kaplan-Meier survival estimates. The results here reported are mostly in accordance with findings reported in previous works.

Angiology ◽  
2021 ◽  
pp. 000331972110280
Author(s):  
Sukru Arslan ◽  
Ahmet Yildiz ◽  
Okay Abaci ◽  
Urfan Jafarov ◽  
Servet Batit ◽  
...  

The data with respect to stable coronary artery disease (SCAD) are mainly confined to main vessel disease. However, there is a lack of information and long-term outcomes regarding isolated side branch disease. This study aimed to evaluate long-term major adverse cardiac and cerebrovascular events (MACCEs) in patients with isolated side branch coronary artery disease (CAD). A total of 437 patients with isolated side branch SCAD were included. After a median follow-up of 38 months, the overall MACCE and all-cause mortality rates were 14.6% and 5.9%, respectively. Among angiographic features, 68.2% of patients had diagonal artery and 82.2% had ostial lesions. In 28.8% of patients, the vessel diameter was ≥2.75 mm. According to the American College of Cardiology lesion classification, 84.2% of patients had either class B or C lesions. Age, ostial lesions, glycated hemoglobin A1c, and neutrophil levels were independent predictors of MACCE. On the other hand, side branch location, vessel diameter, and lesion complexity did not affect outcomes. Clinical risk factors seem to have a greater impact on MACCE rather than lesion morphology. Therefore, the treatment of clinical risk factors is of paramount importance in these patients.


2021 ◽  
Vol 296 ◽  
pp. 113665
Author(s):  
Gamze Gürcan ◽  
Şevin Hun Şenol ◽  
A. Elif Anıl Yağcıoğlu ◽  
Aygün Ertuğrul

2013 ◽  
Vol 57 (6) ◽  
pp. 569 ◽  
Author(s):  
Smita Prakash ◽  
Amitabh Kumar ◽  
Shyam Bhandari ◽  
Parul Mullick ◽  
AnoopRaj Gogia ◽  
...  

2011 ◽  
Vol 26 (8) ◽  
pp. 1774-1782 ◽  
Author(s):  
Teresa A Hillier ◽  
Jane A Cauley ◽  
Joanne H Rizzo ◽  
Kathryn L Pedula ◽  
Kristine E Ensrud ◽  
...  

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