Stenosis or Occlusion of the Right Subclavian and Common Carotid Arteries Is More Common than That of the Innominate Artery in Takayasu Arteritis

Management of the symptomatic multiple stenosis of supra-aortic vessels (MSSVs) in a “bovine” aortic arch (BAA) configuration is infrequently reported. The optimal treatment choice remains debatable. A successful hybrid treatment for a proximal critical stenosis of the innominate and left common carotid artery was performed in a high-risk patient with a tandem symptomatic lesion in the right carotid bifurcation and a concentric vulnerable plaque in the bovine trunk. This case supports the feasibility, safety, and efficacy of a combined carotid bifurcation endarterectomy and retrograde kissing stenting of common carotid arteries with cerebral protection after evaluation of radiological, anatomical, and clinical parameters.

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Ligature of the Right Subclavian (third division) and the Right Common Carotid Arteries, at a Single Operation, on account of Aortic Aneurism; with a Condensed History of the Distal Ligature for Aneurisms near the Heart

The American Journal of the Medical Sciences ◽

10.1097/00000441-188101000-00014 ◽

1881 ◽

Vol 81 (161) ◽

pp. 155-185

Author(s):

John A. Wyeth

Keyword(s):

Carotid Arteries ◽

Aortic Aneurism ◽

Single Operation ◽

History Of ◽

The Right ◽

Common Carotid Arteries

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Effect of a six-month treatment with lanreotide on cardiovascular risk factors and arterial intima-media thickness in patients with acromegaly

Acta Endocrinologica ◽

10.1530/eje.0.1460303 ◽

2002 ◽

pp. 303-309 ◽

Cited By ~ 49

Author(s):

A Colao ◽

P Marzullo ◽

G Lombardi

Keyword(s):

Cardiovascular Risk ◽

Disease Control ◽

Carotid Arteries ◽

Glycosylated Hemoglobin ◽

Hdl Cholesterol ◽

Intima Media Thickness ◽

Media Thickness ◽

Igf I ◽

The Right ◽

Common Carotid Arteries

OBJECTIVE: To evaluate the effect of a 6-month treatment with slow-release lanreotide (LAN) on cardiovascular risk and atherosclerosis in 24 normotensive patients with active acromegaly (GH=67.4 +/- 12.6 mU/l, IGF--I=866.0 +/- 55.8 microg/l) and 24 healthy subjects sex-, age- and body mass index-matched with the patients (as controls). DESIGN: Open, prospective, multicenter. METHODS: The following were measured before and after 6 months of LAN treatment (dose 60-90 mg/month): fasting GH, IGF-I, LDL, HDL and total cholesterol, triglyceride, glucose, glycosylated hemoglobin, insulin and fibrinogen levels, intima-media thickness (IMT) and blood systolic and diastolic peak velocity (SPV and DPV respectively) in both common carotids. RESULTS: At study entry, insulin, total and LDL cholesterol, triglyceride and fibrinogen levels were higher while HDL cholesterol levels were lower in patients than in controls. At the right (0.88 +/- 0.04 vs 0.77 +/- 0.03 mm, P=0.05) and left (0.93 +/- 0.03 vs 0.78 +/- 0.02 mm, P=0.01) common carotid IMT was significantly higher in patients than in controls; 12 patients and two controls showed an IMT of > or = 1 mm (chi(2)=8.2, P=0.004). After 6 months of LAN treatment, disease control was achieved in 15 patients (62.5%). Insulin, triglyceride and fibrinogen levels were significantly decreased, and a trend toward a decrease of IMT in the right (from 0.90 +/- 0.05 to 0.78 +/- 0.04 mm, P=0.06) and left (from 0.95 +/- 0.04 to 0.84 +/- 0.04 mm, P=0.06) common carotid arteries was observed only in patients with disease control, while SPV and DPV did not change. CONCLUSIONS: LAN treatment for 6 months significantly lowered GH, IGF-I, insulin and fibrinogen levels and reduced IMT of both common carotid arteries in normotensive patients with acromegaly.

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Dynamic transduction properties of in situ baroreceptors of rabbit aortic depressor nerve

AJP Heart and Circulatory Physiology ◽

10.1152/ajpheart.1998.274.1.h358 ◽

1998 ◽

Vol 274 (1) ◽

pp. H358-H365 ◽

Cited By ~ 21

Author(s):

Takayuki Sato ◽

Toru Kawada ◽

Toshiaki Shishido ◽

Hiroshi Miyano ◽

Masashi Inagaki ◽

...

Keyword(s):

Transfer Function ◽

White Noise ◽

Innominate Artery ◽

Operating Pressure ◽

Frequency Range ◽

Aortic Depressor Nerve ◽

The Right ◽

Common Carotid Arteries ◽

Made In

We developed a new method for isolating in situ baroreceptor regions of the rabbit aortic depressor nerve (ADN) and estimated the transfer function from pressure to afferent nerve activity in the frequency range of 0.01–5 Hz by a white noise technique. Complete isolation of the baroreceptor area of the right ADN was made in situ by ligation of the innominate artery and the right subclavian and common carotid arteries. We altered the pressure in the isolated baroreceptor area according to a binary quasi-white noise between 80 and 100 mmHg in 12 urethan-anesthetized rabbits. The gain increased two to three times as the frequency of pressure perturbation increased from 0.01 to 2 Hz and then decreased at higher frequencies. The phase slightly led below 0.2 Hz. The squared coherence value was >0.8 in the frequency range of 0.01–4 Hz. The step responses estimated from the transfer function were indistinguishable from those actually observed. We conclude that the baroreceptor transduction of the ADN is governed by linear dynamics under the physiological operating pressure range.

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Collateral Arteries of the Aortic Arch in Mongolian Gerbil (Meriones unguiculatus)

Acta Scientiae Veterinariae ◽

10.22456/1679-9216.89371 ◽

2018 ◽

Vol 46 (1) ◽

pp. 8

Author(s):

Radan Elvis Matias de Oliveira ◽

Hélio Norberto De Araújo Júnior ◽

Herson Da Silva Costa ◽

Gleidson Benevides De Oliveira ◽

Carlos Eduardo Bezerra De Moura ◽

...

Keyword(s):

Aortic Arch ◽

Subclavian Artery ◽

Carotid Arteries ◽

Left Subclavian Artery ◽

Meriones Unguiculatus ◽

Brachiocephalic Artery ◽

Collateral Arteries ◽

Brachiocephalic Trunk ◽

The Right ◽

Common Carotid Arteries

Background: Gerbils (Meriones unguiculatus) are rodents belonging to the Muridae family. Recently, breeding of this species as pets has increased significantly. Animal models are being investigated to study diseases related to the human aortic arch. Despite the importance of the aortic arch in maintaining homeostasis, there is limited data available regarding its morphology in gerbils. This study was performed with the objective of describing the collateral branches of the aortic arch in this animal to establish a standard model and thus contribute to future research on cardiovascular diseases in humans.Materials, Methods & Results: This study used 20 male specimens from previous studies that were frozen and stored at the Laboratory of Veterinary Anatomy of the Federal Rural University of the Semi-Arid Region. After thawing the animals, the thoracic cavity was opened for aortic cannulation. The vascular system was washed using saline solution and Neoprene latex stained with red pigment was injected. Subsequently, the animals were fixed in 10% formaldehyde and were dissected and analyzed 72 h later. The arrangement of the collateral branches of the aortic arch in gerbils was analyzed in all animals. The brachiocephalic trunk, the left common carotid, and the left subclavian artery were observed to originate as collateral branches. The brachiocephalic trunk bifurcated into the right common carotid and the right subclavian arteries. The right and the left subclavian arteries branched into the vertebral artery, the internal thoracic artery, the superficial cervical artery, the costocervical trunk, and the axillary artery.Discussion: Several studies reported in the literature describe the collateral branches of the aortic arch in domestic and wild mammalian species. These studies examined the main arteries that originate directly from the aortic arch and their respective branches, and classified the different anatomical variants of the aortic arch in each species. Three different arrangements have been commonly described. The first type corresponds only to the brachiocephalic artery originating from the aortic arch. The right and the left common carotid arteries and the right and the left subclavian arteries originate from this brachiocephalic artery. This type has already been described in the laboratory rat, catingueiro-deer, cattle, and horses. The second type is characterized by the presence of 2 arteries - the brachiocephalic trunk and the left subclavian artery. The right and the left common carotid arteries and the right subclavian artery originate from the brachiocephalic trunk. This arrangement has been reported in most species already studied such as rodents including the paca, chinchilla, guinea pig, mocó, nutria and the preá. The third type of vascular arrangement is observed in the gerbil. In this species, 3 collateral arteries originate from the aortic arch (the brachiocephalic trunk, the left common carotid, and the left subclavian artery). The right common carotid and the right subclavian artery originate from the brachiocephalic trunk. This vascular model has been described in the manatee, in humans, mice, sauim, and the monkey-nail. Thus, we concluded that the branching pattern of the aortic arch of the gerbil was characterized by the brachiocephalic trunk, the left common carotid, and the left subclavian artery, as has been described in mice, the manatee, monkey-nail, sauim, and humans. Based on these morphological characteristics, gerbils could serve as potential experimental models to study diseases related to the human aortic arch.

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The morphology of the arteries originating from the arcus aorta and the branches of these arteries in mole-rats (Spalax leucodon)

Veterinární Medicína ◽

10.17221/6918-vetmed ◽

2013 ◽

Vol 58 (No. 7) ◽

pp. 373-376 ◽

Cited By ~ 1

Author(s):

A. Aydin ◽

ZE Ozkan ◽

R. Ilgun

Keyword(s):

Aortic Arch ◽

Carotid Arteries ◽

Axillary Artery ◽

Common Root ◽

Brachiocephalic Trunk ◽

Cervical Artery ◽

The Common ◽

Aortic Arch Arteries ◽

The Right ◽

Common Carotid Arteries

In this study, the aim was to investigate the anatomy of the aortic arch arteries in mole-rats (Spalax leucodon). Six adult mole-rats were used for this purpose. Coloured latex was injected into the left ventriculus of the hearts of all animals. The materials were carefully dissected and the arterial patterns of arteries originating from the aortic arch were examined. The brachiocephalic trunk, the left common carotid and the left subclavian arteries were detached from the aortic arch. The brachiocephalic trunk separated into the right subclavian and common carotid arteries. The branches separating from the subclavian arteries were on the right, the common branch giving the profund cervical, the internal thoracic, and the costocervical trunk, and on the left the internal thoracic and the costocervical trunk were in the common root and the profund cervical artery was independent and on both sides after giving the common branch of the superficial servical and the external thoracic artery. This continued as the axillary artery which was then separated into the subscapular and the brachial arteries. Thus, the arteries originating from the aortic arch and the branches of these arteries were found to be different from other rodents and domestic mammals.  

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Endovascular Treatment of Innominate Artery Occlusion With Simultaneous Vertebral and Carotid Artery Distal Protection

Neurosurgery ◽

10.1227/01.neu.0000367549.33541.34 ◽

2010 ◽

Vol 66 (4) ◽

pp. E843-E844 ◽

Cited By ~ 16

Author(s):

Michael F. Stiefel ◽

Min S. Park ◽

Cameron G. McDougall ◽

Felipe C. Albuquerque

Keyword(s):

Carotid Artery ◽

Carotid Arteries ◽

Innominate Artery ◽

Artery Occlusion ◽

Left Middle Cerebral Artery ◽

Arterial Access ◽

Atherosclerotic Stenosis ◽

Protection Devices ◽

Distal Protection ◽

The Right

Abstract OBJECTIVE Atherosclerotic stenosis or obstruction of the innominate artery is rare. Traditional surgical management is a technically demanding intervention with acceptable, but not negligible, rates of morbidity and mortality. Endovascular approaches to supraaortic lesions have been successful and are now the preferred treatment for stenoses of the brachiocephalic vessels. The use of cerebral protection devices in subclavian and innominate interventions is less established. CLINICAL PRESENTATION A 58-year-old woman had Takayasu giant cell arteritis with a history of a left middle cerebral artery stroke 3 weeks after undergoing placement of a left common carotid artery (CCA) stent and right innominate artery stent in 1998. She recently presented with worsening dizziness, ataxia, and right arm numbness and was referred to the endovascular neurosurgery service for management. INTERVENTION Initial angiography revealed left CCA stenosis and right innominate occlusion. The patient initially underwent left CCA angioplasty, planned as a staged procedure. This was followed by recanalization of the right innominate artery through an approach using both femoral arteries and the right brachial artery. This 3-site technique allowed simultaneous distal protection of both the right cervical vertebral and carotid arteries. CONCLUSION Reopening a chronically occluded innominate artery risks an embolic shower through both the right vertebral and carotid arteries. Using multiple sites of arterial access, distal protection devices can be deployed in both the cervical vertebral and carotid arteries to reduce the risk of stroke.

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