scholarly journals Neurochemistry in the Pathophysiology of Septic Encephalopathy

10.5772/35380 ◽  
2012 ◽  
Author(s):  
Yukio Imamura ◽  
Huan Wang ◽  
Naoya Matsumoto ◽  
Hiroshi Ogura ◽  
Takeshi Shimazu ◽  
...  
Keyword(s):  
Septic Encephalopathy

Blood-brain barrier derangement in sepsis: Cause of septic encephalopathy?

1981 ◽  
Vol 141 (1) ◽  
pp. 136-142 ◽  
Author(s):  
Bengt Jeppsson ◽  
Herbert R. Freund ◽  
Zvi Gimmon ◽  
J.Howard James ◽  
Maarten F. von Meyenfeldt ◽  
...  
Keyword(s):  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Septic Encephalopathy ◽  
Blood Brain

Septic Encephalopathy

2002 ◽  
pp. 748-753
Author(s):  
G. B. Young
Keyword(s):  
Septic Encephalopathy

scholarly journals Early Prediction and Outcome of Septic Encephalopathy in Acute Stroke Patients With Nosocomial Coma

2015 ◽  
Vol 7 (7) ◽  
pp. 534-539 ◽  
Author(s):  
Dao-Ming Tong ◽  
Ye-Ting Zhou ◽  
Guang-Sheng Wang ◽  
Xiao-Dong Chen ◽  
Tong-Hui Yang
Keyword(s):  
Acute Stroke ◽  
Early Prediction ◽  
Septic Encephalopathy ◽  
Stroke Patients

Electroencephalographic Grading of Neuronal Dysfunction in Various Etiologies of Encephalopathy

2020 ◽  
Vol 51 (6) ◽  
pp. 420-425
Author(s):  
Fahad Alkhamis ◽  
Saima Nazish
Keyword(s):  
Clinical Outcomes ◽  
Cross Sectional Study ◽  
Neuronal Dysfunction ◽  
Septic Encephalopathy ◽  
Kingdom Of Saudi Arabia ◽  
Cross Sectional ◽  
Continuous Eeg ◽  
Continuous Eeg Monitoring ◽  
Gcs Score ◽  
Ischemic Encephalopathy

Objective: The objective of this work was to study the electroencephalographic (EEG) grading of neuronal dysfunction in encephalopathy of various etiologies and assess their association with clinical outcomes. Subjects and Methods: This retrospective cross-sectional study was performed between June and November 2018 at the Neurology Department of King Fahd Hospital of University, Kingdom of Saudi Arabia (KSA) and involved a review and analysis of EEG and medical records pertaining to 222 patients in whom encephalopathy was diagnosed. Results: In patients suffering from encephalopathy, advanced age ( P = .01), low Glasgow Coma Scale (GCS) scores ( P = .00), and certain etiologies, namely hypoxic-ischemic encephalopathy (HIE) ( P = .00), septic encephalopathy ( P = .01), and other illnesses ( P = .00), were significantly associated with unfavorable clinical outcomes, whereas traumatic brain injury (TBI) ( P = .01) and GCS >7 ( P = .00) were associated with favorable outcomes. Among different etiologies, EEG grade I ( P = .02) and grade IV ( P = .04) neuronal dysfunction was significantly associated with TBI while grade III ( P = .05) and grade V ( P = .02) neuronal dysfunction was significantly associated with HIE. Grade I ( P = .03) neuronal dysfunction was mostly observed in septic encephalopathy cases, while patients suffering from other illnesses were also found to have grade I ( P = .04) and grade IV ( P = .05) neuronal dysfunction based on their EEG. Conclusion: EEG is being conducted routinely to determine the course and severity of various forms of encephalopathy. However, the clinical implications of EEG grading for neuronal dysfunction are largely dependent on underlying etiology and other clinical parameters, such as age and GCS score. Further larger prospective cohort studies involving other important prognostic parameters and continuous EEG monitoring are thus needed.

scholarly journals The role of impaired brain perfusion in septic encephalopathy

Critical Care ◽  
2019 ◽  
Vol 23 (1) ◽  
Author(s):  
Lucia Rivera-Lara
Keyword(s):  
Brain Perfusion ◽  
Septic Encephalopathy

Alpha Coma Pattern in a Child

2008 ◽  
Vol 39 (4) ◽  
pp. 206-209 ◽  
Author(s):  
J. A. Bragatti ◽  
A. M. Mattos ◽  
H. Bastos ◽  
R. S. Riesgo
Keyword(s):  
Drug Overdose ◽  
Metabolic Disorders ◽  
Clinical Case ◽  
Rhythmic Activity ◽  
Septic Encephalopathy ◽  
Alpha Frequency ◽  
Neurological Conditions ◽  
Alpha Coma ◽  
Eeg Pattern ◽  
Ischemic Encephalopathy

Alpha coma, an EEG pattern characterized by diffuse or widespread rhythmic activity in the alpha frequency band, is typically recorded in patients with profound coma and is frequently associated with severe neurological conditions. The most common etiologic factors of this pattern are hypoxic-ischemic encephalopathy, encephalitis, head trauma, metabolic disorders, and drug overdose. Reports of alpha coma pattern in children are relatively common. Clinical significance, both in children and adults, is variable, and highly dependent on etiology. The objective of this article is to report a clinical case of alpha coma pattern in a child with neuroblastoma. The EEG pattern was recorded during the evolution of treatment, secondary to complicating septic encephalopathy. The alpha coma pattern was replaced by a normal trace following a favorable outcome after sepsis resolution.

Pathophysiology of septic encephalopathy: A review

2000 ◽  
Vol 28 (8) ◽  
pp. 3019-3024 ◽  
Author(s):  
Marios C. Papadopoulos ◽  
D. Ceri Davies ◽  
Ray F. Moss ◽  
Derek Tighe ◽  
E. David Bennett
Keyword(s):  
Septic Encephalopathy

scholarly journals Septic Encephalopathy Characterized by Acute Encephalopathy with Biphasic Seizures and Late Reduced Diffusion and Early Nonconvulsive Status Epilepticus

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Hiroshi Yamaguchi ◽  
Tsukasa Tanaka ◽  
Azusa Maruyama ◽  
Hiroaki Nagase
Keyword(s):  
Status Epilepticus ◽  
Febrile Seizure ◽  
Immune Reaction ◽  
Brain Dysfunction ◽  
Nonconvulsive Status Epilepticus ◽  
Acute Encephalopathy ◽  
Septic Encephalopathy ◽  
Impaired Consciousness ◽  
Neurologic Symptom ◽  
Early Seizure

Infection, whether viral or bacterial, can result in various forms of brain dysfunction (encephalopathy). Septic encephalopathy (SE) is caused by an excessive immune reaction to infection, with clinical features including disturbed consciousness and seizures. Acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) is usually accompanied by viral infection in children and is characterized by biphasic seizures and impaired consciousness. The initial neurologic symptom of AESD is typically a febrile seizure that frequently lasts longer than 30 minutes. However, the possible forms this seizure takes are unclear. For example, it is unknown if nonconvulsive status epilepticus (NCSE) could be an early seizure symptomatic of AESD. In addition, thus far no cases of combined SE and AESD have been reported. Here, we describe the first reported case of SE with AESD that notably demonstrated NCSE as an early seizure.

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