scholarly journals Treatment of Neuropathic Pain in Brachial Plexus Injuries

Author(s):  
Nieves Saiz-Sapena ◽  
Vicente Vanaclocha-Vanaclocha ◽  
José María Ortiz-Criado ◽  
L. Vanaclocha ◽  
Nieves Vanaclocha

2021 ◽  
Author(s):  
Erickson Duarte Bonifácio de Assis ◽  
Wanessa Kallyne Nascimento Martins ◽  
Carolina Dias de Carvalho ◽  
Clarice Martins Ferreira ◽  
Ruth Gomes ◽  
...  

Abstract Neuropathic pain (NP) after brachial plexus injury (NPBPI) is a highly disabling clinical condition and is increasingly prevalent due to increased motorcycle accidents. Currently, no randomized controlled trials have evaluated the effectiveness of non-invasive brain stimulation techniques such as Repetitive Transcranial Magnetic Stimulation (rTMS) and Transcranial Direct-Current Stimulation (tDCS) in patients suffering from NPBPI. In this study, we directly compare the efficacy of 10-Hz rTMS and anodal 2 mA tDCS techniques applied over the motor cortex (5 daily consecutive sessions) in 21 patients with NPBPI, allocated into 2 parallel groups (active or sham). The order of the sessions was randomised for each of these treatment groups according to a crossover design and separated by a 30-day interval. Scores for “continuous” and “paroxysmal” pain (primary outcome) were tabulated after the last stimulation day and 30 days after. Secondary outcomes included the improvement in multidimensional aspects of pain, anxiety state and quality of life. Active rTMS and tDCS were both superior to sham in reducing continuous (p < 0,001) and paroxysmal pain (p = 0.04) as well as in multidimensional aspects of pain and anxiety state. Repetitive TMS was superior to tDCS in reducing continuous (p = 0.01) and paroxysmal pain (p = 0.03), and in improving multidimensional aspects of pain (p = 0.01). Our results suggest rTMS and tDCS are able to treat NPBPI with little distinction in pain and anxiety state, which may promote the use of tDCS in brachial plexus injury pain management, as it constitutes an easier and more available technique.



2019 ◽  
Vol 67 (7) ◽  
pp. 32 ◽  
Author(s):  
AnaCarolina Lovaglio ◽  
Mariano Socolovsky ◽  
Gilda Di Masi ◽  
Gonzalo Bonilla




Neurosurgery ◽  
2019 ◽  
Vol 66 (Supplement_1) ◽  
Author(s):  
Erin McCormack ◽  
Mansour H Mathkour ◽  
Lora Wallis Kahn ◽  
Reda Tolba ◽  
Maged Guirguis ◽  
...  

Abstract INTRODUCTION Central neuropathic pain (CNP) and complex regional pain syndrome (CRPS) present as chronic, unrelenting, and disabling pain resulting from central and peripheral nervous system injuries. For patients who have failed conservative management, dorsal root entry zone (DREZ) lesioning may serve as an alternative for the management of intractable pain. METHODS A 36-yr-old male presented with complete right brachial plexus injury and avulsion of nerve roots following a motorcycle accident. He developed disabling type I CRPS of the right upper extremity. After failing medical therapy, he underwent a trial of conventional SCS using 2 percutaneous leads in the upper cervical spine but did not get topographical coverage. He underwent a second SCS trial with the placement of a paddle lead using burst therapy, but his initial partial pain relief subsided after 3 d. Subsequently, he underwent SCS removal, C2 to T1 right DREZ lesioning, and C4 to T1 laminoplasty. The patient gained a significant pain relief and became more functional. Five months postoperatively, he experienced an improvement in his pain and narcotic consumption. RESULTS Using an insulated neurotomy electrode, 2-mm-deep lesions were made at 75°C for 15 s. A total of 83 lesions were made from T2 to C3. Each lesion was spaced 1 mm apart. The impedance was less than 1000 ohms, which was consistent within an area of injury. Somatosensory and motor-evoked potentials were at baseline during the case without significant changes. CONCLUSION When SCS fails, lesioning of the dorsal root entry zone is a useful tool in the armamentarium for the management of refractory brachial plexus neuropathic pain.



2019 ◽  
Vol 27 (3) ◽  
pp. 587-588
Author(s):  
Nara L. M. Quintão ◽  
Lilian W. Rocha ◽  
Gislaine F. da Silva ◽  
Ana F. Paszcuk ◽  
Marianne N. Manjavachi ◽  
...  




2008 ◽  
Vol 28 (11) ◽  
pp. 2856-2863 ◽  
Author(s):  
N. L. M. Quintao ◽  
G. F. Passos ◽  
R. Medeiros ◽  
A. F. Paszcuk ◽  
F. L. Motta ◽  
...  


Hand Surgery ◽  
2015 ◽  
Vol 20 (01) ◽  
pp. 39-45 ◽  
Author(s):  
Direk Tantigate ◽  
Saichol Wongtrakul ◽  
Torpon Vathana ◽  
Roongsak Limthongthang ◽  
Panupan Songcharoen

Background: In Thailand, brachial plexus injury is a common traumatic injury that affects the function of the upper extremity. The current treatments focus mainly on improving the motor and sensory function. Apart from the motor and sensory deficit, these patients usually suffer from pain. Objective: The purpose of this study was to determine the prevalence and factors that relate to neuropathic pain in patients with brachial plexus injury. Methods: We collected data from March 2008 to July 2011. The DN4 Questionnaire was used to diagnose neuropathic pain in 95 patients. Results: The prevalence of neuropathic pain was as high as 76%. Majority of patients presented with hypoesthesia to pin prick, hypoesthesia to touch and numbness. Severity of neuropathic pain was significantly correlated with the type of brachial plexus injury. There was no difference between demographic characteristics of patients. Conclusion: Our study showed that the prevalence of neuropathic pain was high in brachial plexus injured patients. Therefore, surgeons should be aware of this common, yet underestimated, problem in brachial plexus injured patients.



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