scholarly journals Bilateral Foot Skin Eruption in a Hepatitis C Patient

2020 ◽  
Vol 4 (3) ◽  
pp. 491-492
Author(s):  
Shane Davis ◽  
Angela Creditt
Keyword(s):  
Emergency Department ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Skin Eruption ◽  
Zinc Supplementation ◽  
Case Presentation ◽  
Acral Erythema ◽  
History Of ◽  
Necrolytic Acral Erythema ◽  
One Year

Case Presentation: A 58-year-old female with history of hepatitis C virus presented to the emergency department with a bilateral skin eruption to her feet for one year. Following skin biopsy, the patient was diagnosed with Necrolytic acral erythema (NAE). She was treated with clobetasol ointment, zinc supplementation, and mupirocin, which resulted in improvement in her symptoms. Discussion: NAE is a rash described as sharply demarcated, lichenified plaques on the dorsal foot and is a rare extra-hepatic manifestation of hepatitis C. This case details a patient with a skin eruption consistent with NAE.

scholarly journals Hepatitis C Virus Screening of High-Risk Patients in a Canadian Emergency Department

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Kelsey Ragan ◽  
Anjali Pandya ◽  
Tristan Holotnak ◽  
Katrina Koger ◽  
Neil Collins ◽  
...  
Keyword(s):  
Emergency Department ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
High Risk ◽  
Drug Use ◽  
Hcv Rna ◽  
High Risk Patients ◽  
Risk Patients ◽  
History Of ◽  
Hcv Screening

Background. Approximately 0.7% of the Canadian population is infected with hepatitis C virus (HCV), and many individuals are unaware of their infection. Our objectives were to utilize an emergency department (ED) based point-of-care (POC) HCV screening test to describe our local population and estimate the proportion of high-risk patients in our population with undiagnosed HCV. Methods. A convenience sample of medically stable patients (≥18 years) presenting to a community ED in Calgary, AB, between April and July 2018 underwent rapid clinical screening for HCV risk factors, including history of injection drug use, healthcare in endemic countries, and other recognized criteria. High-risk patients were offered POC HCV testing. Antibody-positive patients underwent HCV-RNA testing and were linked to hepatology care. The primary outcome was the proportion of new HCV diagnoses in the high-risk population. Results. Of the 999 patients screened by survey, 247 patients (24.7%) were high-risk and eligible for testing. Of these, 123 (49.8%) were from HCV-endemic countries, while 63 (25.5%) and 31 (12.6%) patients endorsed a history of incarceration and intravenous drug use (IVDU), respectively. A total of 144 (58.3%) eligible patients agreed to testing. Of these, 6 patients were POC-positive (4.2%, CI 0.9–7.4%); all 6 had antibodies detected on confirmatory lab testing and 4 had detectable HCV-RNA viral loads in follow-up. Notably, 103 (41.7%) patients declined POC testing. Interpretation. Among 144 high-risk patients who agreed to testing, the rate of undiagnosed HCV infection was 4.2%, and the rate of undiagnosed HCV infection with detectable viral load was 2.8%. Many patients with high-risk clinical criteria refused POC testing. It is unknown if tested and untested groups have the same disease prevalence. This study shows that ED HCV screening is feasible and that a small number of previously undiagnosed patients can be identified and linked to potentially life-changing care.

Necrolytic acral erythema: A cutaneous sign of hepatitis C virus infection

2005 ◽  
Vol 53 (2) ◽  
pp. 247-251 ◽  
Author(s):  
Mahmoud A. Abdallah ◽  
Mohamed Y. Ghozzi ◽  
Hoda A. Monib ◽  
Aisha M. Hafez ◽  
Kim M. Hiatt ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Hepatitis C Virus Infection ◽  
Acral Erythema ◽  
Necrolytic Acral Erythema

scholarly journals A Rare Case of Acute Renal Failure Secondary to Rhabdomyolysis Probably Induced by Donepezil

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Osman Zikrullah Sahin ◽  
Teslime Ayaz ◽  
Suleyman Yuce ◽  
Fatih Sumer ◽  
Serap Baydur Sahin
Keyword(s):  
Emergency Department ◽  
Renal Failure ◽  
Creatine Kinase ◽  
Acute Renal Failure ◽  
Rare Case ◽  
Laboratory Studies ◽  
Case Presentation ◽  
History Of ◽  
One Year ◽  
Renal Function Tests

Introduction. Acute renal failure (ARF) develops in 33% of the patients with rhabdomyolysis. The main etiologic factors are alcoholism, trauma, exercise overexertion, and drugs. In this report we present a rare case of ARF secondary to probably donepezil-induced rhabdomyolysis.Case Presentation. An 84-year-old male patient was admitted to the emergency department with a complaint of generalized weakness and reduced consciousness for two days. He had a history of Alzheimer’s disease for one year and he had taken donepezil 5 mg daily for two months. The patient’s physical examination revealed apathy, loss of cooperation, and decreased muscle strength. Laboratory studies revealed the following: urea: 128 mg/dL; Creatinine 6.06 mg/dL; creatine kinase: 3613 mg/dL. Donepezil was discontinued and the patient’s renal function tests improved gradually.Conclusion. Rhabdomyolysis-induced acute renal failure may develop secondary to donepezil therapy.

scholarly journals Low prevalence of necrolytic acral erythema in patients with chronic hepatitis C virus infection

2012 ◽  
Vol 67 (5) ◽  
pp. 962-968 ◽  
Author(s):  
Brian A. Raphael ◽  
Zachariah L. Dorey-Stein ◽  
Jason Lott ◽  
Valerianna Amorosa ◽  
Vincent Lo Re ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Chronic Hepatitis C ◽  
Hepatitis C Virus Infection ◽  
Acral Erythema ◽  
Chronic Hepatitis C Virus ◽  
Necrolytic Acral Erythema ◽  
Low Prevalence

Necrolytic acral erythema in Egyptian patients with hepatitis C virus infection

2006 ◽  
Vol 21 (7) ◽  
pp. 1200-1206 ◽  
Author(s):  
Tarek M El-Ghandour ◽  
Mohammad A Sakr ◽  
Hatem El-Sebai ◽  
Tarek F El-Gammal ◽  
Manal H El-Sayed
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Hepatitis C Virus Infection ◽  
Acral Erythema ◽  
Egyptian Patients ◽  
Necrolytic Acral Erythema

scholarly journals Necrolytic Acral Erythema in Seronegative Hepatitis C

2017 ◽  
Vol 9 (1) ◽  
pp. 69-73 ◽  
Author(s):  
Ploychompoo Srisuwanwattana ◽  
Vasanop Vachiramon
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Skin Disorder ◽  
Hcv Infection ◽  
Histopathological Findings ◽  
Serologic Marker ◽  
Acral Erythema ◽  
Necrolytic Acral Erythema

Necrolytic acral erythema (NAE) is a distinctive skin disorder. The exact cause and pathogenesis is still unclear. Most studies report an association of NAE with hepatitis C virus (HCV) infection. We report a 64-year-old woman who presented with chronic mildly pruritic brownish to erythematous rashes on both lateral malleoli for 7 months. The clinical and histopathological findings were compatible with NAE. However, the serologic marker for HCV was negative.

scholarly journals Necrolytic acral erythema: a rare skin disease associated with hepatitis C virus infection

2016 ◽  
Vol 91 (5) ◽  
pp. 649-651 ◽  
Author(s):  
Luciane Francisca Fernandes Botelho ◽  
Milvia Maria Simões e Silva Enokihara ◽  
Mauro Yoshiaki Enokihara
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Skin Disease ◽  
Hepatitis C Virus Infection ◽  
Acral Erythema ◽  
Necrolytic Acral Erythema
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