scholarly journals Human Parvovirus B19 Infection Among Blood Donors in North-East of Iran

2020 ◽  
Vol 15 (4) ◽  
Author(s):  
Ameneh Karimnia ◽  
Ameneh Elikaei ◽  
Zohreh Sharifi
Keyword(s):  
Viral Genome ◽  
Blood Donors ◽  
Parvovirus B19 ◽  
Risk Groups ◽  
Human Parvovirus B19 ◽  
Serum Samples ◽  
Igg Antibody ◽  
Enveloped Virus ◽  
North East ◽  
Golestan Province

Background: Human parvovirus B19 is a single-stranded DNA and non-enveloped virus which belongs to the Parvoviridae family. The virus spreads through respiratory secretions and perinatal blood. B19 may cause serious complications in patients with cellular immunodeficiency that have no detectable antibodies to B19, such as aplastic crises in solid organs. Objectives: The present study aimed to investigate the prevalence of parvovirus B19 and to evaluate the presence of B19 DNA among blood donors in Golestan Province. Methods: Sera of 400 blood donors in Golestan Province who were negative for HIV, HbsAg, and HCV were tested for both IgG and IgM anti-B19 virus antibodies using the ELISA method, following which all sera were tested for the presence of B19 DNA by semi-nested PCR. Results: 242 (out of 400) subjects (60.5%; 95% CI) were positive for anti-B19 IgG, and 158 were negative for IgG antibody (39.5%; 95% CI). Moreover, all asymptomatic blood donors were negative for anti-B19 IgM. No viral genome was found in serum samples of donors. Conclusions: Since no viral genome was found in the donors' serum samples and the relatively high prevalence of anti HPV- B19 IgG in blood donors, it can be concluded that the possibility of B19 transmission through blood transfusion is low. However, special caution should be taken when transfusing blood to the high-risk groups such as pregnant women, immune-deficient patients, and those with hematological problems, particularly regarding IgG anti- HPV- B19 antibodies (HPV- B19-safe).

scholarly journals The prevalence of antibody to human parvovirus B19 in Rio de Janeiro, Brazil

1990 ◽  
Vol 32 (1) ◽  
pp. 41-45 ◽  
Author(s):  
Jussara P. Nascimento ◽  
Marie M. Buckley ◽  
Kevin E. Brown ◽  
Bernard J. Cohen
Keyword(s):  
Rio De Janeiro ◽  
Parvovirus B19 ◽  
Human Parvovirus B19 ◽  
Antibody Prevalence ◽  
Serum Samples ◽  
Igg Antibody ◽  
Males And Females ◽  
Aged Eleven

During 1985 and 1986 serum samples were collected from the Rio de Janeiro population and examined for the presence of IgG antibody to human parvovirus B19. No difference in prevalence was found between males and females. Antibody prevalence rose from 35% in children less than five years old to almost 80% in children aged eleven to fifteen years. The antibody prevalence in individuals over 50 years old was over 90%.

Persistent infection by human parvovirus B19 in qualified blood donors

Transfusion ◽  
2008 ◽  
Vol 48 (5) ◽  
pp. 1036-1037 ◽  
Author(s):  
Harumichi Matsukura ◽  
Sachiko Shibata ◽  
Yoshihiko Tani ◽  
Hirotoshi Shibata ◽  
Rika A. Furuta
Keyword(s):  
Persistent Infection ◽  
Blood Donors ◽  
Parvovirus B19 ◽  
Human Parvovirus B19

The formation and modification of chromatin-like structure of human parvovirus B19 regulate viral genome replication and RNA processing

2017 ◽  
Vol 232 ◽  
pp. 134-138 ◽  
Author(s):  
Huanzhou Xu ◽  
Sujuan Hao ◽  
Junmei Zhang ◽  
Zhen Chen ◽  
Hanzhong Wang ◽  
...  
Keyword(s):  
Rna Processing ◽  
Viral Genome ◽  
Parvovirus B19 ◽  
Genome Replication ◽  
Human Parvovirus B19 ◽  
Viral Genome Replication

Human Parvovirus B19 Infection in Blood Donors

Vox Sanguinis ◽  
1995 ◽  
Vol 69 (3) ◽  
pp. 206-212 ◽  
Author(s):  
M. Tsujimura ◽  
K. Matsushita ◽  
H. Shiraki ◽  
H. Sato ◽  
K. Okochi ◽  
...  
Keyword(s):  
Blood Donors ◽  
Parvovirus B19 ◽  
Human Parvovirus B19 ◽  
Parvovirus B19 Infection

scholarly journals Genotype 1 of human parvovirus B19 in clinical cases

2017 ◽  
Vol 63 (3) ◽  
pp. 224-228 ◽  
Author(s):  
Maria Isabel de Oliveira ◽  
Ana Maria Sardinha Afonso ◽  
Suely Pires Curti ◽  
Patrícia Evelin Silva ◽  
Tamyris Fernanda Barbosa ◽  
...  
Keyword(s):  
Parvovirus B19 ◽  
Infectious Agent ◽  
Immunoglobulin M ◽  
Human Parvovirus B19 ◽  
Genotype 1 ◽  
Serum Samples ◽  
Chronic Anemia ◽  
Virus Surveillance ◽  
Polymerase Chain

Summary Introduction: Virus surveillance strategies and genetic characterization of human parvovirus B19 (B19V) are important tools for regional and global control of viral outbreak. In São Paulo, Brazil, we performed a study of B19V by monitoring the spread of this virus, which is an infectious agent and could be mistakenly reported as a rash and other types of infection. Method: Serum samples were subjected to enzyme immunoassay, real time polymerase chain reaction, and sequencing. Results: From the 462 patients with suspected cases of exanthematic infections, the results of the 164 serum samples were positive for B19V immunoglobulin M. Among these cases, there were 38 patients with erythema infections and B19-associated with other infections such as encephalitis, hydrops fetalis, chronic anemia, hematological malignancies. These samples were sequenced and identified as genotype 1. Conclusion: This study showed patients with infections caused by B19V and sequencing genotype 1. Continuous monitoring is necessary to detect all known genotypes, and the emergence of new genotypes of these viruses for case management in public health control activities.

scholarly journals Seroprevalence of human parvovirus B19 in healthy blood donors

2013 ◽  
Vol 69 (3) ◽  
pp. 268-272 ◽  
Author(s):  
Satish Kumar ◽  
R.M. Gupta ◽  
Sourav Sen ◽  
R.S. Sarkar ◽  
J. Philip ◽  
...  
Keyword(s):  
Blood Donors ◽  
Parvovirus B19 ◽  
Human Parvovirus B19

scholarly journals Seroprevalence of parvovirus B19 IgG and IgM antibodies among pregnant women in Oyo State, Nigeria

2013 ◽  
Vol 7 (12) ◽  
pp. 946-950 ◽  
Author(s):  
Iyanda Abiodun ◽  
Oluyinka Oladele Opaleye ◽  
Olusola Ojurongbe ◽  
Ademola Hezekiah Fagbami
Keyword(s):  
Pregnant Women ◽  
Parvovirus B19 ◽  
First Trimester ◽  
Intrauterine Fetal Death ◽  
Human Parvovirus B19 ◽  
Second Trimester ◽  
Igg Antibody ◽  
Southwestern Nigeria ◽  
Igm Antibodies ◽  
Wide Range

Introduction: Human parvovirus B19 causes a wide range of complications in pregnant women including abortion, severe fetal anemia, non-immune hydrops fetalis, and even intrauterine fetal death. However, there is a dearth of information on the prevalence of the virus among pregnant women in southwestern Nigeria. Methodology: Blood samples were collected from 231 pregnant women and screened for antibodies to human parvovirus B19 IgM and IgG using an enzyme immunosorbent assay kits. Results: Of the 231 women, 31 were in their first trimester, 146 were in their second trimester, and 54 were in their third trimester. Forty-five (20%) were positive for parvovirus B19 IgG antibodies, 10 (4%) were positive for parvovirus B19 IgM antibodies, and 176 (76%) had no detectable parvovirus B19 antibodies. Twenty-eight (19%) of the 146 pregnant women in their second trimester were positive for parvovirus B19 IgG antibody while three (2%) of the 146 were positive for parvovirus B19 IgM antibody. Conclusions: It is evident that there is a high prevalence of human parvovirus B19 among pregnant women in south-western Nigeria. This suggests that there is an active transmission of the virus in the community; it is therefore necessary to conduct more studies on the virus in pregnant women in Nigeria to ascertain its effect on the fetus.

scholarly journals Seroprevalence of Toxoplasma gondii in the Rural Population of Qaemshahr, Northern Iran in 2019

2021 ◽  
Vol 8 (1) ◽  
pp. 34-38
Author(s):  
Eissa Soleymani ◽  
Afshin Azimi ◽  
Fariba Faizi ◽  
Shirafkan Kordi ◽  
Mazaher Azorde ◽  
...  
Keyword(s):  
Toxoplasma Gondii ◽  
Rural Population ◽  
Public Health Education ◽  
Raw Milk ◽  
Risk Groups ◽  
Serum Samples ◽  
Igg Antibody ◽  
Chi Square ◽  
Northern Iran ◽  
Soil P

Background: Toxoplasmosis is a worldwide infection caused by Toxoplasma gondii, an obligate intracellular protozoan. It infects approximately one-third of the world’s population. This study was conducted to determine the anti-T. gondii antibodies (IgG and IgM) in the rural population of Qaemshahr, northern Iran, in 2019. Methods: Serum samples of 350 individuals referred to the laboratories of the rural health centers in Qaemshahr, northern Iran, were collected from February to April 2019 and were assessed for anti-T. gondii antibodies (IgG and IgM) using the ELISA kits (Pishtazteb, Iran). The results were analyzed using the chi-square test. Results: Totally, 296 (84.57%, 95% CI: 80.07%-88.2%) out of 350 serum samples were positive for anti-T. gondii IgG antibody. There was a significant correlation between seropositivity of anti-T. gondii IgG antibody and age (P=0.000), contact with soil (P=0.000), and job. None of the samples were positive for anti-T. gondii IgM antibody. No significant association was observed between the seroprevalence of T. gondii and the gender, contact with the cat and other animals, and ingestion of undercooked meat, non-chlorinated water, undercooked egg, raw milk and vegetables. Conclusions: Results of the study showed that the prevalence of toxoplasmosis was much higher among the rural individuals in Qaemshahr, northern Iran, than those previously reported from other areas of Iran. Therefore, efforts should be focused on public health education to reduce the risk of toxoplasmosis transmission especially in the high-risk groups in this region.

Sign in / Sign up

Export Citation Format

Share Document