scholarly journals A Case Report of COVID-19 in a Pregnant Woman with Clinical Manifestations of Chorioamnionitis in Ilam, Iran

Author(s):  
Nasrin Rashan ◽  
Mona Bahmani ◽  
Ashraf Direkvand-Moghadam

Introduction: Confrontation with COVID-19 has threatened all people of the world, including pregnant women, as a high-risk group. Case Presentation: The present study presents a 29-year-old female G1P0 at 33 weeks’ gestation. The patient’s initial complaint was the premature rupture of membranes. The patient’s vital signs showed an abnormal pulse rate and temperature. Initial assessments were carried out, including regular monitoring and recording of vital signs, mother’s blood ABG, uterine contractions, laboratory tests, and fetal heart rate. Treatment for chorioamnionitis began with intravenous ampicillin, gentamicin, and oral erythromycin. Because of the epidemic of COVID-19 in Iran and Ilam, a throat swab specimen was obtained from the upper respiratory tract of the patient. The RT-PCR assay confirmed that the throat swab sample of the patient was positive for COVID-19. A throat swab specimen was taken from the newborn for RT-PCR. Also, the mother’s chest CT scan was done that showed abnormality; however, the RT-PCR throat swab specimen was negative for the newborn. The patient was transferred to the COVID-19 care unit. She was healthily discharged from the hospital with two negative RT-PCR tests. Her newborn was followed for two weeks, and no symptoms of COVID-19 were reported. Conclusions: Some major prenatal complications, including fetal distress, preterm labor, premature rupture of membranes, and amniotic fluid abnormalities, have been reported among some pregnant women infected with COVID-19 (7); however, the clinical manifestations of COVID-19 are deceptive. Therefore, low attention to all aspects of COVID-19 and late examination would increase the risk of spreading the disease among therapists providing services and other hospitalized mothers. These concerns make pregnant mothers afraid of even the most necessary referrals for appropriate and necessary midwifery interventions. Therefore, it is necessary to pay attention to two important issues: first, the concerns and anxieties of pregnant mothers and second, making the diagnosis in suspected cases as soon as possible.

2021 ◽  
pp. 38-40
Author(s):  
Najya Nasrin K Z ◽  
Anitha S Prabhu ◽  
Mithun H K ◽  
Shyam Sudhir

MATERIAL & METHOD: This retrospective study was conducted during the period of June-August 2020 for 3months in newborns born to COVID-19 positive mothers at YMCH after obtaining ethical clearance. All newborns born to mothers with COVID-19 positive status during any trimester of pregnancy, irrespective of neonatal COVID-19 RT-PCR test, and delivered at YMCH during the study period were included. Relevant history and complete systemic examination ndings of the neonate were noted down from the case records and laboratory results of RT-PCR test on nasopharyngeal and throat swab if done was noted down which was done at 24-48hours of birth.RESULT:Total of 25newborns born to COVID-19 positive mothers were included in the study. Among the neonates born, 64% were female and 36% were male. 76% of the pregnant mothers were asymptomatic at the time of detection of COVID-19 infection. The neonatal outcome found to have only 1 newborn with positive COVID-19 infection compared to 24 healthy newborns. CONCLUSION: Signicant measures for preventing neonatal SARS-CoV-2 infection are to prevent maternal illness and to decrease the potential of neonatal viral exposure.


2020 ◽  
Vol 222 (1) ◽  
pp. S295-S296
Author(s):  
Young Mi Jung ◽  
Seung Mi Lee ◽  
Jae Seong Oh ◽  
Seo Hyun Yoon ◽  
Joo-Youn Cho ◽  
...  

2019 ◽  
Vol 2019 ◽  
pp. 1-9
Author(s):  
Nengneng Zheng ◽  
Renyong Guo ◽  
Yinyu Yao ◽  
Meiyuan Jin ◽  
Yiwen Cheng ◽  
...  

Vaginal dysbiosis has been identified to be associated with adverse pregnancy outcomes, such as preterm delivery and premature rupture of membranes. However, the overall structure and composition of vaginal microbiota in different trimesters of the pregnant women has not been fully elucidated. In this study, the physiological changes of the vaginal microbiota in healthy pregnant women were investigated. A total of 83 healthy pregnant participants were enrolled, who are in the first, second, or third pregnancy trimester. Quantitative real-time PCR was used to explore the abundant bacteria in the vaginal microbiota. No significant difference in the abundance of Gardnerella, Atopobium, Megasphaera, Eggerthella, Leptotrichia/Sneathia, or Prevotella was found among different trimesters, except Lactobacillus. Compared with the first pregnancy trimester, the abundance of L. iners decreased in the second and third trimester while the abundance of L. crispatus was increased in the second trimester. Moreover, we also found that vaginal cleanliness is correlated with the present of Lactobacillus, Atopobium, and Prevotella and leukocyte esterase is associated with Lactobacillus, Atopobium, Gardnerella, Eggerthella, Leptotrichia/Sneathia, and Prevotella. For those whose vaginal cleanliness raised or leukocyte esterase became positive, the richness of L. iners increased, while that of L. crispatus decreased significantly. Our present data indicated that the altered vaginal microbiota, mainly Lactobacillus, could be observed among different trimesters of pregnancy and L. iners could be considered as a potential bacterial marker for evaluating vaginal cleanliness and leukocyte esterase.


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