scholarly journals Using Montelukast as an Add-on Treatment in Nephrotic Syndrome Pediatrics: A Randomized Clinical Trial Study

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Fatemeh Javidi ◽  
Parsa Yousefichaijan ◽  
Fatemeh Dorreh ◽  
Ali Arjmand ◽  
Masoud Rezagholizamenjany

Background: Montelukast, as a non-steroidal anti-inflammatory drug, could reduce inflammation in nephrotic syndrome (NS). This study aimed to evaluate the therapeutic effect of montelukast as adjunctive therapy in pediatric NS. Methods: This clinical trial study was conducted on patients with NS. The patients were assigned into two equal groups (N = 25 in each) of intervention (steroid + montelukast) and control and treated for one month. One month later, in the follow-up stage, their proteinuria was measured. The results before and after treatment were statistically analyzed by SPSS software version 21, and the final report of the project was presented. Results: The age of participants in the intervention and control groups was 7.26 ± 4.23 and 6.79 ± 3.91 years, respectively (P = 0.68), and there were 10 female participants in both groups (P = 1.0). Albumin levels in 96% of the control group and 76% of the intervention group were 1.5 - 2.5 μg/dL (P = 0.037). Also, 48% of participants in the control group were corticosteroid dependent, and 60% of participants in the intervention group responded to corticosteroids (P = 0.194). The severity of nephrotic syndrome was moderate in 60% of participants in the control group and mild in 60% of participants in the intervention group (P = 0.138). Conclusions: The results of this study showed that recovery rate was higher in the intervention group, but the difference was not statistically significant.

Author(s):  
Dewi Siyamti ◽  
Eka Adimayanti ◽  
Hapsari Windayanti

Background: Dysmenorrhea is uncomfort symptom which suffered by adolescents during menstruation period. Adolescents experienced with dysmenorrhea and this commonly primary. Dysmenorrhea affects almost half of all woman, and it is need the safe and effective pain management. One of non-medical treatment techniques is acupressure. The purpose of this study to analize the effect of acupressure to reduce dysmenorrhea in adolescents. Methods: The design was quantitative experiment with intervention group and control group for each 26 respondents. The acupoints are SP6, Li4, and PC6. Intervention group got acupressure for 2 days in early period with 30times massage for each accupoint twice a day. The pain was measured using visual analog scale (VAS) before and after intervention. Data analize using SPSS software. Results: The result showed diffreneces in pain severity after acupressure to intervention group with mean 2,43 and p value 0.027(p<0,005). Conclution: Acupressure at the SP6, Li4 and PC6 can reduce pain severity of dysmenorrhea in adolescents.


Background and Aims: Fear of delivery in females can lead to negative side effects, such as the experience of long and hard labor. Reduction of delivery fear is one of the goals of natural delivery program, and hypnosis has been considered a way to reduce this fear. With regard to the contradictory results of the studies in this field, this study aimed to determine the effect of self-hypnosis on the experience of delivery fear and duration of labor in primiparity. Materials and Methods: This clinical trial was conducted on 63 pregnant women who were divided into self-hypnosis (n=30) and control groups (n=33) using a blocking method in Mashhad, Iran, during 2019. The intervention group received two sessions of hypnosis at 37th and 38th weeks of pregnancy which consisted of listening to an audio file until delivery time. On the other hand, the control group received only the routine care. Fear was evaluated at 37th week of pregnancy and 24 h after delivery. Data were analyzed using SPSS software (version 16), and a p-value less than 0.05 was considered statistically significant. Results: The mean scores of delivery fear experience (P<0.001), as well as the duration of the second stage (P=0.013) and third stage of labor (P=0.009) were significantly lower in the self-hypnosis group, compared to the controls. Conclusion: Self-hypnosis was effective in reducing the experience of delivery fear and duration of the second and third stages of labor in primiparity. Therefore, self-hypnosis is recommended to reduce the experience of delivery fear and duration of the second and third stages of labor in primiparity.


2019 ◽  
Vol 103 (2) ◽  
pp. 157-172 ◽  
Author(s):  
Angelika Kullberg ◽  
Camilla Björklund ◽  
Irma Brkovic ◽  
Ulla Runesson Kempe

AbstractIn this paper, we report how 5-year-olds’ arithmetic skills developed through participation in an 8-month-long intervention. The intervention program aimed to enhance the children’s ways of experiencing numbers’ part-part-whole relations as a basis for arithmetic skills and was built on principles from the variation theory of learning. The report is based on an analysis of assessments with 103 children (intervention group n = 65 and control group n = 38) before and after the intervention and a follow-up assessment 1 year after the intervention. Our findings show that the learning outcomes of the intervention group were significantly higher compared to those of the control group after the intervention and that differences between the groups remained even 1 year after the intervention. In particular, the results show that children participating in the intervention group learned to recognize and use part-part-whole relations in novel arithmetic tasks.


2017 ◽  
Vol 11 (2) ◽  
pp. 100
Author(s):  
Aprizal Satria Hanafi ◽  
Qomariyatus Sholihah

Unlocked energy in the machine can cause heavy equipment to move suddenly, it can hit the mechanics that are working. LOTO devices are required in this case. LOTO is a locking and labeling system for energy sources so that occupational accidents can be prevented. This study aim to know the difference of occupational accident cases on heavy equipment mechanics before and after using LOTO devices. A quasy experiment approach was used to evaluate occupational accidents. This design uses two group, intervention group, and control group, 32 heavy equipment mechanics were given LOTO device and 32 heavy equipment mechanics were not given LOTO device.Based on pre-evaluation, evaluation 1, and evaluation 2  there is a decrease in the number of occupational accidents in the intervention group after given LOTO device. Statistical test showed there was a difference in occupational accidents before and after the use of LOTO device on heavy equipment mechanics based on type of accidents (beaten, p = 0.001), (falling, p = 0.005), (pinched, p = 0.001), (pressed, p = 0.001), (crushed, p = 0.000).LOTO devices proved to be effective in preventing and reducing the number of occupational accidents in the heavy equipment mechanics.


2017 ◽  
Vol 3 (3) ◽  
pp. 229-237 ◽  
Author(s):  
Nikmah Jalilah Ritonga ◽  
Onny Setiani ◽  
Umaroh Umaroh ◽  
Kamilah Budhi R ◽  
Faisal Amri

Background: Roselle flower (Hibiscus sabdariffa) has been used as a food and herbal drinks, in hot and cold beverages, as a herbal medicine.Objective: To examine the effect of consuming roselle dried flower petals on changes in maternal hypertensive blood pressure during postpartum period.Methods: This was a quasi-experimental study with non-equivalent control group design conducted in 2016. There were 30 samples recruited using consecutive sampling with 15 samples in the intervention group and control group. Data were analyzed using paired t-test to know the difference of blood pressure value before and after intervention in the intervention and control group, and Independent t-test  to determine the difference of blood pressure decrease between intervention and control group. Mann-whitney and Wilcoxon test were also performed for data analysis.Results: Findings showed that there were statistically significant differences in systolic and diastolic blood pressure values before and after intervention in the intervention and control group with p-value 0.000 <0.05 with systolic blood pressure decrease was 5 mmHg and diastolic was 5.33 mmHg. Additionally, there was a significant effect in the duration of healing in the intervention group with p-value 0.000 <0.05, with the average duration of healing was 2 days.Conclusion: There was significant effects of dried petals of rosella flowers (Hibiscus sabdariffa) brewed with 200 ml of hot water with temperature 90oC in lowering blood pressure, and there was significant differences in systolic and diastolic blood pressure and duration of healing between the intervention and control group of mothers who consumed antihypertensive drugs. The results of this study can be applied by midwives in postpartum care with the cases of hypertension. It is expected that this intervention can help the healing process more quickly through a combination of antihypertensive medicines and sedated petals of rosella flowers.


2021 ◽  
Vol 12 ◽  
pp. 215145932110291
Author(s):  
Atsuko Satoh ◽  
Yukoh Kudoh ◽  
Sangun Lee ◽  
Masumi Saitoh ◽  
Miwa Miura ◽  
...  

Introduction: To evaluate fall-prevention rehabilitative slippers for use by self-caring, independent older adults. Materials and Methods: This assessor-blinded, randomized, and controlled 1-year study included 59 self-caring, independent participants (49 women) who attended day services. The mean age of participants was 84.0 ± 5.3 years. Participants were randomly selected from 8 nursing homes. We tested slippers top-weighted with a lead bead (200, 300, or 400 g). Intervention group participants walked while wearing the slippers for 10-20 min, 1-3 days/week at the day service center. Fall risk was measured using the Berg Balance Scale and the Tinetti Performance-Oriented Mobility Assessment (POMA) before and at 3-month intervals after the intervention/control phase. Results: After 12 months, the intervention group demonstrated significant improvement. Berg Balance and POMA compared to the control group ( p < .05 p < .01, respectively). Mobility scores improved significantly for both measurements in the intervention group before and after ( p < .01), but the control group had significantly lower scores. Discussion: Overall, falls decreased in the intervention group from 10 to 7, and control group falls increased from 9 to 16 ( p = .02). No adverse events related to the intervention were reported. Conclusions: Rehabilitation training slippers may reduce falls in older adults.


Author(s):  
Asieh Mehdipour ◽  
Parvin Abedi ◽  
Somayeh Ansari ◽  
Maryam Dastoorpoor

Abstract Objectives Postmenopausal women are at greater risk of depression. Depression may negatively affect the quality of life of women. An emotional freedom technique (EFT) is an evidence-based therapy combining cognitive and exposure components with acupressure. This study aimed to evaluate the effect of EFT on depression in postmenopausal women. Methods This was a randomized controlled trial in which 88 women with mild to moderate depression recruited from a menopausal clinic in Ahvaz, Iran, and randomly assigned into two groups of EFT (n=44) and control for sham therapy (n=44). Women in the EFT group received two sessions of training and asked to continue EFT for 8 weeks, one time per day. The Beck Depression Inventory (BDI2) completed by women before and after the intervention. The control group received training on sham acupressure points similar to the intervention group. Data collected using a demographic and BDI2. Women requested to complete the BDI2 before and after the intervention. The independent t-test, chi-square, and ANCOVA were used to analyze data. Results The mean depression score in the intervention group reduced from 20.93 ± 4.6 to 10.96 ± 4.38 in comparison to the control group that reduced from 19.18 ± 2.79 to 17.01 ± 6.05 after intervention (p=0.001). After the 8 week intervention, the frequency of moderate depression decreased from 56.8 to 9.35% in the intervention and from 50 to 29.5% in the control group. In total, 63.4 and 34.15% in the intervention and control groups were free of depression respectively after the intervention (p<0.001). Conclusions The results of this study showed that using EFT for 8 weeks could significantly reduce the mean score of depression in postmenopausal women. Using this method in public health centers for postmenopausal women is recommended.


Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Jaime Céspedes ◽  
German Briceño ◽  
Michael Farkouh ◽  
Rajesh Vedanthan ◽  
Martha Leal ◽  
...  

Introduction: Educational programs for children can increase uptake of healthy lifestyle behaviors. However, the impact of educational programs in preschool-aged children in low- and middle-income countries is not known. We conducted a five month educational intervention in preschool facilities (PF) in Bogota, Colombia, to assess changes in preschooler’s knowledge, attitudes and habits (KAH) towards healthy eating and living an active lifestyle. Methods: We conducted a cluster, randomized, controlled trial, and randomly assigned 14 PF in Bogota to a five-month educational intervention (7 PF) or to usual curriculum (7 PF). The intervention included classroom activities and use of printed material and videos. A total of 1216 pre-school children, 928 parents, and 120 teachers participated. A structured survey was used to evaluate changes in KAH with a weighted total score (WTS). The primary outcome was change in children's WTS, and the secondary outcomes were change in parents’ and teachers' WTS. The control PF were provided the intervention after the initial evaluation. To assess sustainability, we evaluated both intervention and control groups at 18 months. Results: At 6 months, children in the intervention group showed 10.9% increase in WTS vs. 5.3% in controls, p<0.001, after adjustment for cluster, sex, age and teachers' educational level. Among parents, the equivalent results were 8.9% and 3.1%, respectively, p< 0.001, and among teachers 9.4% and 2.5%, p=0.06. At the 18-month extended follow-up, both the intervention and control children showed a significant further increase in WTS, p<0.001 (Figure 1). In parents and teachers in the intervened group, there was no significant increase in WTS, p=0.7417, and p=0.1197. In the control group, there was an increase in WTS in teachers but not in parents, p=0.001, and p=0.4239. Conclusion: A preschool based intervention, aimed at changing KAH related to healthy diet and active lifestyle, is feasible, efficacious and sustainable up to 18 months in very young children in Colombia.


2019 ◽  
Vol 8 ◽  
Author(s):  
Babak Geraiely ◽  
Roya Sattarzadeh Badkoubeh ◽  
Maryam Jalalsafari ◽  
Nazila Shahmansouri ◽  
Anahita Tavousi ◽  
...  

Background: As an invasive modality, a coronary angioplasty may cause a great deal of anxiety in patients and affect their mental health and general well-being. Accordingly, we sought to assess whether showing patients the video of their elective percutaneous coronary intervention (angiogram) could affect their illness perception and anxiety level. Materials and Methods: In this randomized clinical trial, the patients undergoing angioplasty, were randomly divided into two groups of 30 patients. Angiograms were shown only to the intervention group postprocedurally. A checklist comprising demographic data and clinical presentations as well as the Beck anxiety questionnaire and the Brief Illness Perception Questionnaire (BIPQ) was completed for each patient immediately after the intervention and one month later. The differences in the patients’ anxiety level and illness perception were analyzed. Results: In the intervention group, the mean anxiety score before and after watching the angiograms was 34.26 ± 8.1 and 24.4 ± 8.56, respectively. While in the control group, the score before and after angioplasty was 34.46 ± 9.34 and 26.6 ± 9.44, respectively. Thus, watching angiograms led to a significant decrease in the anxiety score in the intervention group, whereas there was no such difference in the control group. There was also a considerable difference in the anxiety score between the two groups. Further, there was a significant decrease in the BIPQ score of the intervention group after watching the angioplasty videos. Conclusion: Educating cardiovascular patients about diagnostic and therapeutic procedures may confer such good outcomes as alleviated anxiety, enhanced satisfaction, and ultimately, fewer anxiety-related complications. [GMJ.2019;8:e1556]


2022 ◽  
Author(s):  
Forouzandeh Soleimanian-Boroujeni ◽  
Negin Badihian ◽  
Shervin Badihian ◽  
Vahid Shaygannejad ◽  
Yousef Gorji

Abstract Introduction: Psychological interventions are shown to be effective in migraine, but not utilized routinely yet. We aimed to evaluate the efficacy of transdiagnostic cognitive behavioral therapy (TCBT) on people with migraine (PwM). Method: This study was conducted on 40 PwM aged 20-50 years. We randomly assigned participants to two groups of intervention, receiving 10 sessions of TCBT, and control. Days with headache, headache severity, migraine-related disability and effects on daily life, number of pain-relivers taken for headache, depression, and anxiety were assessed pre-intervention, post-intervention (three-month follow-up), and one-month after TCBT termination (four-month follow-up).Results: Thirty-five participants suffering moderate to severe migraine completed the study (16 and 19 in TCBT and control groups, respectively). TCBT improved all measured items between study time-points (p<0.05) in the intervention group, while such an improvement was not observed in the control group. Between group comparisons revealed superiority of TCBT group compared to the control group in most measured items at three- and four-month follow-ups (p<0.05).Conclusion: Ten sessions of TCBT improved migraine severity, associated disability, anxiety, and depression in PwM, with persistent effects after one month of therapy termination. TCBT is an affordable, practical, and feasible intervention to be utilized for PwM.Protocol registration: The study protocol was registered in clinicaltrial.gov (NCT03701477) prior to enrollment.


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