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2023 ◽  
Vol 83 ◽  
Author(s):  
K. R. Jones ◽  
G. W. Garcia

Abstract Anthelmintic drugs have been used strategically in livestock reared in the tropics. These drugs have been used in the treatment of endoparasitism which have resulted in an increase in the animals’ performance. The agouti (Dasyprocta leporina) is a neo-tropical rodent with the potential for domestication and has been farmed intensively in Trinidad. However, the objective of this research was to investigate the effect of anthelmintic use of the growth performance of the agouti. In searching the literature, it was found that this type of study on the agouti has not been done. In this experiment fourteen weaned agoutis weighing 1kg were divided into two groups randomly. The first group (T1) was not given any anthelmintic treatment but the second group (T2) was treated with Endovet Ces® subcutaneously every three months. There were no significant differences (p > 0.05) between the two groups in the carcass weight, weight gain, dressing percentage (hot and cold), heart, lungs, skin, head and feet. However, a significant difference (p < 0.05) was seen between groups in the weight of liver and pluck. To the authors knowledge this is the first time that carcass parameters has been presented in literature. The live weight of the animals at the end of the experiment ranged from 2.4 kg to 2.6 kg and animals had a dressing percentage of 57% to 55%. The results are suggestive that the use of anthelmintic drugs in agoutis reared intensively had no significant effect on weight gain and dressing percentage.


2022 ◽  
Vol 12 (1) ◽  
pp. 64
Author(s):  
Nicolò Zarotti ◽  
Maria Dale ◽  
Fiona J. R. Eccles ◽  
Jane Simpson

Huntington’s disease (HD) is a rare and complex condition where affected individuals, family members, caregivers, and clinicians face a number of both long-term and fluctuating challenges. The predominant biomedical framework adopted in HD to date has traditionally viewed it as a brain disorder first and foremost. As a consequence, one of the most challenging aspects of the condition—psychological difficulties and their care—is often not given the emphasis it deserves in everyday clinical practice. Here, we propose a manifesto outlining five points to address the quality, effectiveness, availability, and accessibility of psychological care in HD. These include (1) Listening to People with HD, (2) Reformulating Difficulties Psychologically, (3) Exploring New Interventions, (4) Increasing Psychological Provision, and (5) Learning from Other Conditions. As the search for a cure continues, we hope that this manifesto will create a new impetus towards refining the current approach to psychological difficulties in HD and ultimately improve the quality of life of the tens of thousands of families affected by HD worldwide.


Author(s):  
Laura Murray

This article is an attempt to frontally pose a question queer theory gravitates around, yet never effectively spells out: what is a togetherness of those who have nothing in common but their desire to undo group ties? First, I consider the take-up of Lacan’s ethical experiment in Seminar VII, the Ethics of Psychoanalysis by queer theorists. I contend that queer theory has not given Lacan’s interpretation of Antigone its full import, which demands its placement in the philosophical tradition of the West brought to its highest fruition in Kant. I further contend, however, that to do so does not quite offer a solution to the queer problem, for, as contemporary debate on the political import of Antigone shows, the purity of her desire does not immediately translate into a sustainable politics. Lacan himself was faced with the problem of translating his ethics into a politics after his "excommunication" from the psychoanalytic establishment, and came to falter before it. Nevertheless, Lacan’s efforts allow us to pose the undoubtedly queer question of how to group together those whose only attribute is to undo group ties. Responding to the unanswerable demands of a theory and a practice that allows us to answer that question, I propose the figure of the smoker’s communism, as elaborated upon by Mladen Dolar, as a preliminary queer suggestion as to how we might go about mitigating the gap between Lacan’s ethical brilliance and his admitted political failure..


JUSTISI ◽  
2022 ◽  
Vol 8 (1) ◽  
pp. 30
Author(s):  
Nicky Winata ◽  
Winsherly Tan

Cartels as a Form of Unfair Business Competition KPPU often has difficulty proving it through direct evidence in accordance with Law No. 5/1999, so the alternative used by KPPU to obtain evidence is indirect evidence, and in practice this indirect evidence It is also not easy because it has not been regulated in Law No. 5/1999 so that the Supreme Court has not given any information regarding indirect evidence. The research method used by the author is normative research using library research to obtain data, and there is a need for clarity regarding procedural law from the KPPU. And the Authority of the KPPU in order to facilitate the handling of the KPPU on the Cartel Problem in Indonesia and amid the uncertainty of indirect evidence, the leniency of the program can also be used as an alternative in proving the occurrence of cartel actions carried out by business actors, and the application of evidence is not This directly was also adopted by other countries as well as the leniency program, and Indonesia also needs to follow this step to reduce cartels in Indonesia.


2022 ◽  
Vol 73 ◽  
pp. 1-65
Author(s):  
Jan Maly

The problem of lifting a preference order on a set of objects to a preference order on a family of subsets of this set is a fundamental problem with a wide variety of applications in AI. The process is often guided by axioms postulating properties the lifted order should have. Well-known impossibility results by Kannai and Peleg and by Barbera and Pattanaik tell us that some desirable axioms – namely dominance and (strict) independence – are not jointly satisfiable for any linear order on the objects if all non-empty sets of objects are to be ordered. On the other hand, if not all non-empty sets of objects are to be ordered, the axioms are jointly satisfiable for all linear orders on the objects for some families of sets. Such families are very important for applications as they allow for the use of lifted orders, for example, in combinatorial voting. In this paper, we determine the computational complexity of recognizing such families. We show that it is \Pi_2^p-complete to decide for a given family of subsets whether dominance and independence or dominance and strict independence are jointly satisfiable for all linear orders on the objects if the lifted order needs to be total. Furthermore, we show that the problem remains coNP-complete if the lifted order can be incomplete. Additionally, we show that the complexity of these problems can increase exponentially if the family of sets is not given explicitly but via a succinct domain restriction. Finally, we show that it is NP-complete to decide for a family of subsets whether dominance and independence or dominance and strict independence are jointly satisfiable for at least one linear order on the objects.


2022 ◽  
Vol 8 (1) ◽  
pp. 25-29
Author(s):  
Elita Marintan ◽  
Brian Wasita ◽  
Adi Magna

Background: Alzheimer's disease (AD) is a neurodegenerative disorder marked by brain inflammation resulted in structural damage and brain dysfunction. Tumor necrosis factor α (TNFα) is a cytokine that plays an important role in inflammation. Dates fruit may help to fight oxidative stress and inflammation in the brain. Objective: To determine the effect of date fruit extracts on blood TNFα levels and brain weight of alzheimer’s model rats. Methods: This research is a laboratory experimental study by post-test only with control group design using alzheimer model rats. This study used 6 treatment groups with simple randomization. Each treatment group was represented by 8 Sprague Dawley rats. The normal control group (KN) was not induced by Hcy and was not given date palm extract, the negative control group (K-) was the Alzheimer's experimental rats which was not given the date palm extract, the positive group was the Alzheimer's experimental rats which was given the Donepezil (K+). Groups P1, P2, P3 were Alzheimer's experimental rats that were given date palm extract at a dose of 200, 400,800 mg / kgBW / day. The effect of date palm extract dosage on TNFα levels and brain weight were analyzed using the One Way Anova test followed by Tukey's post hoc test. Results: The difference in TNFα levels between groups showed a significant difference (p = 0.00). Meanwhile there was no significant difference in brain weight among all groups (p > 0,05). Conclusion: Date palm extract at doses of 200, 400, 800 mg / kgBW can decrease blood TNFα levels of Alzheimer’s model rats.


2021 ◽  
Vol 12 (4) ◽  
pp. 796-799
Author(s):  
Saurabh Bajirao Kadam ◽  
Shital Rahul Rasane ◽  
Atul Viraj Wadagale

Background: According to Ayurveda, the HIV Symptoms may be correlated with Rajayakshama (Kshaya). The Symptoms, causative factors and treatment for the latter were found mentioned in many ancient Ayurvedic texts. Present study was aimed to assess the correlation of Rajayakshama symptoms described in Charak Samhita and symptoms seen in HIV positive patient. Material and Method: Present study was a Cross-sectional Survey Study, conducted in patientsof 25 - 50 years age group, irrespective of sex, religion, economic & marital status, diagnosed patients of HIV antibody test positive minimum 2 year ago.Results: Maximum number of HIV patient were from 31-40 years age group(67%). Majority of HIV patients were Female (81%).53 % patients’ were HIV Antibody Test Positive more than 2 year ago & 47% patients were more than 10 year ago.97 % patients were on ART Medication and only 3% patients were not given ART Medication.Ansatapa, Jwara and Parshwashulawere observed in all 100% patient. other symptoms Shirashula(99%); Aruchi(96%);Swarabheda(94%); Swasa(87%); Kasa(60%), Atisara(51 %); Raktasthivana(12%) and Raktavamana(4%). 69% cases were observed with 8-11 symptoms of Rajayakshma. 30% cases had 5-7 symptoms and only 1% cases had 1-4 symptoms of Rajayakshma.Conclusion: this disease is more related to mental status of the person. Following Dinacharya, Rutucharya, Sadvrittapalana, Aachararasayana etc. explained in Ayurveda will definitely help in treating AIDS and improving patient’s health.


Author(s):  
Parmiana Bangun

Infan is the period as well as the time of Christ's development. It is said to be a critical period because this period is very short for the environment and it is said to be a development period because infancy is not very short and can be repeated again. The most important period of child development is infancy and toddlerhood. In infancy / toddler there is a basic growth that will determine the next child's development. Infancy is the first month of life, the baby will adapt to the environment, changes in blood circulation, and begin to work the organs of the body, and in post-neonatal the baby will experience very fast growth. One way to stimulate growth and development in children is to use the baby solus per aqua (SPA) technique. Babies who are given SPA Babies will certainly grow and develop differently from the growth and development of babies who are not given SPA Babies. This is because the Baby SPA series aims to awaken the baby's sensory and motor nerves early with certain stimuli so that babies can grow actively and be more optimal both physically and mentally. This study aims to obtain an overview of the effect of Infant SPA on weight gain aged 4 to 6 months, Measuring the weight gain of infants aged 4 to 6 months who receive and Infant SPA and those who do not receive massage and Infant SPA at the Tapian Dolok Health Center, Simalungun Regency. The hypothesis in this study is that the increase in the weight of the babies who received the Baby Spa was greater than the standard deviation of the weight gain of 36.9 with a mean difference of 48.7 grams between the two groups. The sample size obtained is 12 respondents so that the number of samples will be increased to 30 according to the minimum sample that can be analyzed statistically. So the intervention group was 30 babies and the control group was 30 babies. The results showed that there was an effect of SPA for infants on weight gain of infants at the age of 4 to 6 months. This study is expected to provide knowledge to mothers who have babies aged 4 6 months the importance of SPA for babies to the baby's weight gain.


Author(s):  
Robert Kemp ◽  
Richard Smith

Access controls are a key area for any security program. However, the recommended access controls cannot always be implemented across the entire organisations. This is the case within critical infrastructure organisations that have both Information Technology and Operational Technology assets where many of the controls cannot be implemented on Operational Technology. Also, safety is a key concern for critical infrastructure organisations which is not always the case with many standard commercial organisations. This means the access controls while maintaining security must not impact safety which can occur if considerations are not given to Operational Technology and safety objectives. This paper will provide ways to manage the conflicts and issues that can occur and provide a process to allow critical infrastructure organisations to implement the required controls without impacting safety and security.


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