Spindle Cell Lipoma of the Parotid

2001 ◽  
Vol 125 (6) ◽  
pp. 820-821 ◽  
Author(s):  
John H. Fasig ◽  
Robert A. Robinson ◽  
Timothy M. McCulloch ◽  
Mavis S. Fletcher ◽  
Carolyn K. Miller

Abstract A 47-year-old man presented to the otolaryngologist with a 7-year history of a mass of the cheek. Fine-needle aspiration revealed foci of spindled cells admixed with abundant fat and myxoid material. A diagnosis of spindle cell lipoma was rendered on the resected specimen. The cytologic findings of spindle cell lipoma of the parotid gland as seen by fine-needle aspiration are presented along with the histologic correlates.

Author(s):  
Jose Ma. C. Avila

This 52-year-old male underwent fine needle aspiration biopsy of a 2cm diameter parotid mass that was firm, well-delineated, and vaguely moveable, The mass was not painful and was noted for about a year.  The aspiration biopsy smear was quite cellular and showed fragments of spindle-shaped cells with cigar shaped nuclei and scanty to indistinct cytoplasms.  Nuclei were vesicular and Verocay-like bodies were identified by cell patterns.  The biopsy was read as a benign spindle cell tumor, probably a schwannoma.   Excision of the mass revealed a typical schwannoma by histopathology. Schwannomas of the parotid gland are rare1 and arise from the intraparotid branches of the facial nerve.   Clues to the cytologic diagnosis include the cellular but benign spindly cell population clustered into Verocay body patterns and evidence of cyst degeneration in the form of histiocytes and even lymphocytes.2 Main differential diagnoses include the predominant spindle cell myoepitheliomas3 and some of the low grade sarcomas that may arise from the parotid gland.   The even rarer schwannomalike mixed tumor of the parotid4 gland must be also considered.


2011 ◽  
Vol 41 (2) ◽  
pp. 171-173 ◽  
Author(s):  
Antonio D'Antonio ◽  
Carlo Baldi ◽  
Domenico Memoli ◽  
Alessia Caleo ◽  
Rosa Rosamilio ◽  
...  

2006 ◽  
Vol 34 (6) ◽  
pp. 455-456 ◽  
Author(s):  
Masood A. Siddiqui ◽  
Lyndon Su ◽  
Claire W. Michael ◽  
Robert T. Pu

Author(s):  
Anu Anna Jacob ◽  
Geethanjali N. ◽  
Usha Poothiode

Pleomorphic lipoma/ spindle cell lipoma accounts for 15 % of lipoma within extremities, confining to the superficial plain comprising lower dermis and subcutaneous tissue. Intramuscular presentation in extrimities is a rare presentation. Here is a case of deep seated pleomorphic lipoma, of forearm, both on fine needle aspiration, biopsy and IHC confirmation. 100% of benign cases of lipoma are positive for CD 34, as stated in many studies and was also positive in our case.


2008 ◽  
Vol 52 (4) ◽  
pp. 495-499 ◽  
Author(s):  
Neelaiah Siddaraju ◽  
Bhawana Ashok Badhe ◽  
Mangala Goneppanavar ◽  
Manisha Manaswini Mishra

2019 ◽  
Vol 103 (1-2) ◽  
pp. 9-14
Author(s):  
Bahadır Öz ◽  
Serap Doğan ◽  
Ertan Emek ◽  
Muhammed Akyüz ◽  
Alper Akcan ◽  
...  

The objective of the current study was to determine the risk of malignancy in patients with thyroid nodules with cytology of indeterminate follicular and indeterminate Hürthle cell neoplasm (HN). The cytologic diagnosis of follicular neoplasm (FN) or HN remains a diagnostic challenge. Often, surgery is recommended for such lesions. A retrospective analysis was performed on 80 patients who underwent thyroid surgery following a diagnosis of indeterminate FN and indeterminate HN in thyroid fine-needle aspiration biopsy. Sex; age; family history of thyroid cancer and radiation exposure; coexisting thyroid conditions, such as solitary nodule; multinodularity; cytologic diagnosis; sonographic features; type of surgical treatment; and histopathologic results were recorded. Of the 80 patients, 52 (65%) had FN on fine-needle aspiration biopsy cytology and 28 (35%) had HN. A total of 23 patients (28.7%) had primary thyroid cancers on surgical pathology, and 57 (71.3%) had benign diagnoses. Univariate analysis showed no differences between the benign and malignant groups by sex, nodule size, family history of thyroid cancer, history of radiation exposure, presence of solitary nodule or multinodularity in the nodular features. In multivariate binary logistic regression analysis, the factors that were statistically significant predictors of malignancy were microcalcification [odds ratio (OR), 10.9; 95% confidence interval (CI), 2.18–54.7; P = 0.004], being older than 45 years (OR, 4.2; 95% CI, 1.25–14.63; P = 0.02]. The independent predictors of malignancy in FN and HN are micorcalcification and being older than 45 years, the use of which may predict the risk of thyroid cancer.


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