Bronchial Epithelial-Myoepithelial Carcinoma

2004 ◽  
Vol 128 (1) ◽  
pp. 92-94 ◽  
Author(s):  
Kun Ru ◽  
Amitabh Srivastava ◽  
Arthur S. Tischler
Keyword(s):  
Immunohistochemical Staining ◽  
Myoepithelial Cells ◽  
Nodal Metastasis ◽  
Myoepithelial Carcinoma ◽  
Heavy Smoking ◽  
Bronchial Epithelial ◽  
Distal Airway ◽  
Pulmonary Neoplasm ◽  
History Of ◽  
Epithelial Myoepithelial Carcinoma

Abstract Epithelial-myoepithelial tumor is extremely rare as a pulmonary neoplasm. Only 20 cases have been reported to date, of which 14 were malignant. We report a case of intrabronchial epithelial-myoepithelial carcinoma in a 73-year-old man with a history of heavy smoking. The tumor was well-circumscribed and caused distal airway obstruction. Histologically, the tumor showed glandular and solid architecture. The glands were composed of an inner layer of epithelial cells and an outer layer of myoepithelial cells. The solid areas consisted of spindle-shaped myoepithelial cells. Immunohistochemical staining was positive for p53 and c-Kit (CD117). Focal atypia and increased mitotic activity were present, but no vascular invasion or nodal metastasis was identified.

Recurrent Bronchial Epithelial-Myoepithelial Carcinoma After Local Therapy

2007 ◽  
Vol 8 (6) ◽  
pp. 386-388 ◽  
Author(s):  
Alaa A. Muslimani ◽  
Madappa Kundranda ◽  
Sudhanshu Jain ◽  
Hamed A. Daw
Keyword(s):  
Local Therapy ◽  
Myoepithelial Carcinoma ◽  
Bronchial Epithelial ◽  
Epithelial Myoepithelial Carcinoma

scholarly journals Epithelial-Myoepithelial Carcinoma of the Breast with Rhabdoid Features

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Karl Grenier ◽  
Gulbeyaz Altinel ◽  
Zari Dastani ◽  
Atilla Omeroglu
Keyword(s):  
Clear Cell ◽  
Phyllodes Tumor ◽  
Myoepithelial Cells ◽  
Metaplastic Carcinoma ◽  
Myoepithelial Carcinoma ◽  
Diagnostic Challenge ◽  
Carcinoma Of The Breast ◽  
Epithelial Myoepithelial Carcinoma ◽  
Rhabdoid Differentiation ◽  
Rhabdoid Features

Epithelial-myoepithelial carcinoma of the breast is a rare biphasic tumor composed of intermixed malignant epithelial and myoepithelial components. Myoepithelial cells are known to adopt varied morphologies, including spindle, chondroid, clear cell, and rhabdoid morphologies, and can represent a diagnostic challenge when isolated on biopsy. Rhabdomyosarcoma, phyllodes tumor, metaplastic carcinoma, and myoepithelial carcinoma are primary breast tumors that all have been shown to exhibit rhabdoid features, whether representing true differentiation or morphological mimic. We here report an epithelial-myoepithelial carcinoma of the breast with rhabdoid features in a 76-year-old woman. The rhabdoid-appearing myoepithelial cells are negative for myogenin, consistent with a rhabdoid-like morphology rather than a true rhabdoid differentiation, comparably to previously described myoepithelial carcinoma with rhabdoid features. To our knowledge, this is the first reported case of epithelial-myoepithelial carcinoma of the breast with rhabdoid features and thus adds another entity to the differential diagnosis of breast lesions with rhabdoid features.

scholarly journals Primary Epithelial Myoepithelial Carcinoma of Lung, Reporting of a Rare Entity, Its Molecular Histogenesis and Review of the Literature

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Farzana Arif ◽  
Susan Wu ◽  
Shahriyour Andaz ◽  
Stewart Fox
Keyword(s):  
Incidental Finding ◽  
Lower Lobe ◽  
Final Diagnosis ◽  
Myoepithelial Cells ◽  
Myoepithelial Carcinoma ◽  
Rare Entity ◽  
Lobe Bronchus ◽  
Epithelial Myoepithelial Carcinoma ◽  
Bronchial Glands ◽  
The Right

Primary epithelial myoepithelial carcinoma of lung is a rare entity and is thought to arise from the submucosal bronchial glands distributed throughout the lower respiratory tract. Because of the rarity of this tumor, we describe one case of epithelial myoepithelial carcinoma arising in the bronchus intermedius and presenting as an endobronchial mass. A 57-year-old male patient presented with an incidental finding of an endobronchial mass located in the lumen of the right lower lobe bronchus and caused near total luminal occlusion of the bronchus. An endobronchial carcinoid tumor was entertained clinically. Subsequently the patient underwent an uneventful videothoracoscopic lobectomy of lower and middle lobes of the right lung. Morphologically and immunohistochemically the tumor was characterized by two cell populations with epithelial and myoepithelial cells forming duct-like structure. The final diagnosis of epithelial myoepithelial carcinoma of lung was rendered.

Epithelial-Myoepithelial Carcinoma of Salivary Glands

1992 ◽  
Vol 101 (6) ◽  
pp. 540-542 ◽  
Author(s):  
John G. Batsakis ◽  
Adel K. El-Naggar ◽  
Mario A. Luna
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Cell Population ◽  
Phenotypic Expression ◽  
Myoepithelial Cells ◽  
Salivary Gland Neoplasms ◽  
Myoepithelial Carcinoma ◽  
Parotid Glands ◽  
Ductal Cells ◽  
Epithelial Myoepithelial Carcinoma

Epithelial-myoepithelial carcinomas comprise approximately 1 % of all salivary gland neoplasms. They are preponderantly tumors of the parotid glands with a relatively low mortality but a decided locoregional aggressiveness. Histopathologically, the carcinomas are characterized by a dual cell population of epithelial (ductal) cells and myoepithelial cells. These cells vary in their dominance and phenotypic expression

Epithelial-Myoepithelial Carcinoma of the Lung

2003 ◽  
Vol 127 (4) ◽  
pp. e177-e180 ◽  
Author(s):  
Latife Doganay ◽  
Selcuk Bilgi ◽  
Asli Ozdil ◽  
Yener Yoruk ◽  
Semsi Altaner ◽  
...  
Keyword(s):  
S100 Protein ◽  
Lower Lobe ◽  
Malignant Neoplasm ◽  
Myoepithelial Cells ◽  
Low Grade ◽  
Myoepithelial Carcinoma ◽  
Primary Lung Tumors ◽  
Pulmonary Parenchyma ◽  
Epithelial Myoepithelial Carcinoma ◽  
Bronchial Glands

Abstract Primary lung tumors mimicking the salivary gland–type neoplasms are extremely rare. These types of tumors originate from submucosal bronchial glands. Epithelial-myoepithelial carcinoma is an uncommon tumor in this group, and only 7 cases have been reported. It is considered to be a low-grade malignant neoplasm. We report a case of epithelial-myoepithelial carcinoma of bronchial gland origin in a 73-year-old man who presented with coughing and dyspnea. The bronchus of the left lower lobe contained a tumor mass that had a polypoid growth pattern. The tumor also extended into the pulmonary parenchyma, forming a well-circumscribed mass with a pushing margin. The tumor consisted of epithelial and myoepithelial cells. The epithelial cells were positive for cytokeratins and epithelial membrane antigen, while the myoepithelial cells were positive for S100 protein and muscle-specific actin. According to these findings, we diagnosed epithelial-myoepithelial carcinoma. After undergoing pneumonectomy, the patient has been disease free for 34 months.

scholarly journals p63 expression of clear myoepithelial cells in epithelial-myoepithelial carcinoma of the salivary gland

Cancer ◽  
2005 ◽  
Vol 105 (4) ◽  
pp. 240-245 ◽  
Author(s):  
Akihiko Kawahara ◽  
Hiroshi Harada ◽  
Toshiro Yokoyama ◽  
Masayoshi Kage
Keyword(s):  
Salivary Gland ◽  
Myoepithelial Cells ◽  
Myoepithelial Carcinoma ◽  
Epithelial Myoepithelial Carcinoma

scholarly journals A Rare Case of Bronchial Epithelial-Myoepithelial Carcinoma with Solid Lobular Growth in a 53-Year-Old Woman

2015 ◽  
Vol 78 (4) ◽  
pp. 428 ◽  
Author(s):  
Yoon Jin Cha ◽  
Joungho Han ◽  
Min Ju Lee ◽  
Kyung Soo Lee ◽  
Hojoong Kim ◽  
...  
Keyword(s):  
Rare Case ◽  
Myoepithelial Carcinoma ◽  
Bronchial Epithelial ◽  
Epithelial Myoepithelial Carcinoma

Bronchial epithelial-myoepithelial carcinoma

1998 ◽  
Vol 33 (1) ◽  
pp. 90-91 ◽  
Author(s):  
J H Shanks ◽  
P S Hasleton ◽  
A Curry ◽  
A Rahman
Keyword(s):  
Myoepithelial Carcinoma ◽  
Bronchial Epithelial ◽  
Epithelial Myoepithelial Carcinoma

Bronchial Epithelial-Myoepithelial Carcinoma

2007 ◽  
Vol 83 (2) ◽  
pp. 689-691 ◽  
Author(s):  
Tung-Ying Chao ◽  
An-Shen Lin ◽  
Chien-Hao Lie ◽  
Yu-Hsiu Chung ◽  
Jui-Wei Lin ◽  
...  
Keyword(s):  
Myoepithelial Carcinoma ◽  
Bronchial Epithelial ◽  
Epithelial Myoepithelial Carcinoma

scholarly journals Robotic Resection of Pulmonary Epithelial Myoepithelial Carcinoma: A Case Report

2021 ◽  
Vol 10 (01) ◽  
pp. e42-e44
Author(s):  
Rajika Jindani ◽  
Michael A. Lopez ◽  
Tatiana P. Miquel ◽  
Erik Sylvin
Keyword(s):  
Malignant Neoplasm ◽  
Myoepithelial Carcinoma ◽  
Review Of Literature ◽  
Unique Case ◽  
Endobronchial Lesion ◽  
History Of ◽  
Well Differentiated ◽  
Epithelial Myoepithelial Carcinoma ◽  
Bronchial Glands ◽  
Robotic Resection

Abstract Background Pulmonary epithelial–myoepithelial carcinoma (P-EMC) is an extremely rare, well-differentiated, and malignant neoplasm originating from submucosal bronchial glands in the lung. EMCs arise mainly in the salivary glands. Case Description This case represents an asymptomatic 78-year-old male with a remote 75-pack-year history of smoking who presents with a solitary endobronchial lesion, which is suggestive of a primary lung EMC, detected on annual screening chest computed tomography (CT) scan. Conclusion A recent review of literature reveals less than 50 documented cases of the pulmonary subtype of this tumor worldwide. We are reporting a unique case of robot-assisted pulmonary lobectomy for a P-EMC.

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