scholarly journals Robotic Resection of Pulmonary Epithelial Myoepithelial Carcinoma: A Case Report

2021 ◽  
Vol 10 (01) ◽  
pp. e42-e44
Author(s):  
Rajika Jindani ◽  
Michael A. Lopez ◽  
Tatiana P. Miquel ◽  
Erik Sylvin
Keyword(s):  
Malignant Neoplasm ◽  
Myoepithelial Carcinoma ◽  
Review Of Literature ◽  
Unique Case ◽  
Endobronchial Lesion ◽  
History Of ◽  
Well Differentiated ◽  
Epithelial Myoepithelial Carcinoma ◽  
Bronchial Glands ◽  
Robotic Resection

Abstract Background Pulmonary epithelial–myoepithelial carcinoma (P-EMC) is an extremely rare, well-differentiated, and malignant neoplasm originating from submucosal bronchial glands in the lung. EMCs arise mainly in the salivary glands. Case Description This case represents an asymptomatic 78-year-old male with a remote 75-pack-year history of smoking who presents with a solitary endobronchial lesion, which is suggestive of a primary lung EMC, detected on annual screening chest computed tomography (CT) scan. Conclusion A recent review of literature reveals less than 50 documented cases of the pulmonary subtype of this tumor worldwide. We are reporting a unique case of robot-assisted pulmonary lobectomy for a P-EMC.

Epithelial-Myoepithelial Carcinoma of the Lung

2003 ◽  
Vol 127 (4) ◽  
pp. e177-e180 ◽  
Author(s):  
Latife Doganay ◽  
Selcuk Bilgi ◽  
Asli Ozdil ◽  
Yener Yoruk ◽  
Semsi Altaner ◽  
...  
Keyword(s):  
S100 Protein ◽  
Lower Lobe ◽  
Malignant Neoplasm ◽  
Myoepithelial Cells ◽  
Low Grade ◽  
Myoepithelial Carcinoma ◽  
Primary Lung Tumors ◽  
Pulmonary Parenchyma ◽  
Epithelial Myoepithelial Carcinoma ◽  
Bronchial Glands

Abstract Primary lung tumors mimicking the salivary gland–type neoplasms are extremely rare. These types of tumors originate from submucosal bronchial glands. Epithelial-myoepithelial carcinoma is an uncommon tumor in this group, and only 7 cases have been reported. It is considered to be a low-grade malignant neoplasm. We report a case of epithelial-myoepithelial carcinoma of bronchial gland origin in a 73-year-old man who presented with coughing and dyspnea. The bronchus of the left lower lobe contained a tumor mass that had a polypoid growth pattern. The tumor also extended into the pulmonary parenchyma, forming a well-circumscribed mass with a pushing margin. The tumor consisted of epithelial and myoepithelial cells. The epithelial cells were positive for cytokeratins and epithelial membrane antigen, while the myoepithelial cells were positive for S100 protein and muscle-specific actin. According to these findings, we diagnosed epithelial-myoepithelial carcinoma. After undergoing pneumonectomy, the patient has been disease free for 34 months.

Dedifferentiated Liposarcoma With a Paraganglioma-like Histologic Pattern: A Case Report and Review of the Literature

2004 ◽  
Vol 128 (7) ◽  
pp. 788-791
Author(s):  
Dating Liu ◽  
Guillermo Quinonez ◽  
Steven Latosinsky
Keyword(s):  
Neuron Specific Enolase ◽  
Malignant Neoplasm ◽  
Neuroendocrine Differentiation ◽  
Growth Patterns ◽  
Dedifferentiated Liposarcoma ◽  
Tissue Mass ◽  
Histologic Pattern ◽  
History Of ◽  
Poorly Differentiated ◽  
Well Differentiated

Abstract A 53-year-old man presented with a 4-month history of increasing abdominal discomfort and distension. A large retroperitoneal mass was found on imaging. Image-guided needle core biopsy demonstrated a poorly differentiated malignant neoplasm. A 30 × 32 × 33-cm soft tissue mass was removed. Microscopically, the tumor consisted of predominantly epithelioid malignant cells arranged in a paraganglioma-like growth pattern. Immunohistochemically, these cells were strongly positive for neuron-specific enolase. Stains for synaptophysin and chromogranin, however, were negative. There was no ultrastructural evidence of neuroendocrine differentiation. Adjacent sarcomatous areas were composed of spindled cells arranged in storiform and fibrosarcoma-like growth patterns. A small area of well-differentiated liposarcoma was identified, and a diagnosis of dedifferentiated liposarcoma was established. To the best of our knowledge, this represents the first reported case of dedifferentiated liposarcoma with a paraganglioma-like histologic pattern. A brief review focusing on the morphologic variations of dedifferentiated liposarcoma is also presented.

Bronchial Epithelial-Myoepithelial Carcinoma

2004 ◽  
Vol 128 (1) ◽  
pp. 92-94 ◽  
Author(s):  
Kun Ru ◽  
Amitabh Srivastava ◽  
Arthur S. Tischler
Keyword(s):  
Immunohistochemical Staining ◽  
Myoepithelial Cells ◽  
Nodal Metastasis ◽  
Myoepithelial Carcinoma ◽  
Heavy Smoking ◽  
Bronchial Epithelial ◽  
Distal Airway ◽  
Pulmonary Neoplasm ◽  
History Of ◽  
Epithelial Myoepithelial Carcinoma

Abstract Epithelial-myoepithelial tumor is extremely rare as a pulmonary neoplasm. Only 20 cases have been reported to date, of which 14 were malignant. We report a case of intrabronchial epithelial-myoepithelial carcinoma in a 73-year-old man with a history of heavy smoking. The tumor was well-circumscribed and caused distal airway obstruction. Histologically, the tumor showed glandular and solid architecture. The glands were composed of an inner layer of epithelial cells and an outer layer of myoepithelial cells. The solid areas consisted of spindle-shaped myoepithelial cells. Immunohistochemical staining was positive for p53 and c-Kit (CD117). Focal atypia and increased mitotic activity were present, but no vascular invasion or nodal metastasis was identified.

scholarly journals Primary Epithelial Myoepithelial Carcinoma of Lung, Reporting of a Rare Entity, Its Molecular Histogenesis and Review of the Literature

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Farzana Arif ◽  
Susan Wu ◽  
Shahriyour Andaz ◽  
Stewart Fox
Keyword(s):  
Incidental Finding ◽  
Lower Lobe ◽  
Final Diagnosis ◽  
Myoepithelial Cells ◽  
Myoepithelial Carcinoma ◽  
Rare Entity ◽  
Lobe Bronchus ◽  
Epithelial Myoepithelial Carcinoma ◽  
Bronchial Glands ◽  
The Right

Primary epithelial myoepithelial carcinoma of lung is a rare entity and is thought to arise from the submucosal bronchial glands distributed throughout the lower respiratory tract. Because of the rarity of this tumor, we describe one case of epithelial myoepithelial carcinoma arising in the bronchus intermedius and presenting as an endobronchial mass. A 57-year-old male patient presented with an incidental finding of an endobronchial mass located in the lumen of the right lower lobe bronchus and caused near total luminal occlusion of the bronchus. An endobronchial carcinoid tumor was entertained clinically. Subsequently the patient underwent an uneventful videothoracoscopic lobectomy of lower and middle lobes of the right lung. Morphologically and immunohistochemically the tumor was characterized by two cell populations with epithelial and myoepithelial cells forming duct-like structure. The final diagnosis of epithelial myoepithelial carcinoma of lung was rendered.

scholarly journals A Case of Epithelial-Myoepithelial Carcinoma of Parotid Gland and Analysis of 33 Cases Reported in Korea

2021 ◽  
Vol 37 (2) ◽  
pp. 61-65
Author(s):  
Ji Won Kim ◽  
Min Soo Kim ◽  
Bo Sung Kim ◽  
Seong Dong Kim
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Low Frequency ◽  
Malignant Neoplasm ◽  
Clinicopathological Characteristics ◽  
Low Grade ◽  
Myoepithelial Carcinoma ◽  
Regional Lymph Nodes ◽  
Retrospective Cohort Studies ◽  
Epithelial Myoepithelial Carcinoma

Epithelial-myoepithelial carcinoma is rare, low-grade malignant neoplasm that compromises approximately 1% of all salivary gland neoplasms. We reported a 68-year-old woman with epithelial-myoepithelial carcinoma in the parotid gland. We analyzed demographic and clinicopathological characteristics of salivary gland epithelial-myoepithelial carcinoma which has been reported in 33 cases in Korea from 1992 to 2017, and compared this result to overseas retrospective cohort studies. There was no significance in terms of mean age at diagnosis, the predominance of females, low frequency in regional lymph nodes, and distant metastasis between the two groups. However, T classification and AJCC stage at diagnosis in domestic cases are more advanced than those of overseas cases. Although the recurrence rate in domestic cases has been reported lower than that of overseas, further study may be needed considering that the follow-up period after treatment is short in domestic cases.

scholarly journals Case Report: Nasal Cavity Epithelial-Myoepithelial Carcinoma With High Fluoro-D-Glucose Uptake on Positron Emission Tomography/Computed Tomography

2021 ◽  
Vol 8 ◽  
Author(s):  
Jacques Dzuko Kamga ◽  
Jean-Christophe Leclere ◽  
Arnaud Uguen ◽  
Karim Amrane ◽  
Ronan Abgral
Keyword(s):  
Nasal Cavity ◽  
Fdg Pet ◽  
Tumor Staging ◽  
Malignant Neoplasm ◽  
Myoepithelial Carcinoma ◽  
First Case ◽  
Positron Emission ◽  
Pet Ct ◽  
Epithelial Myoepithelial Carcinoma ◽  
Fdg Pet Ct

Epithelial-myoepithelial carcinoma (EMC) is a rare malignant neoplasm arising most frequently in the salivary glands and exceptionally in the nasal cavity. EMC accounts for ~1–2% of salivary gland tumors. Even if the nodal and distant metastasis rates are low, tumor staging remains indicated. Here, the authors present the 2-deoxy-2-[18F]fluoro-D-glucose PET-CT (18F-FDG-PET/CT) study of a very rare case of biopsy-proven EMC of the left nasal cavity. This 18F-FDG-PET/CT was performed to stage this tumor and guide the therapeutic strategy due to an atypical high-grade presentation in immunohistochemistry. To our knowledge, this is the first case reporting such high 18F-FDG avidity of EMC of the nasal cavity in PET/CT.

An unusual presentation of aggressive epithelial-myoepithelial carcinoma of the nasal cavity with high-grade histology

2011 ◽  
Vol 125 (12) ◽  
pp. 1286-1289 ◽  
Author(s):  
J-O Park ◽  
C-K Jung ◽  
D-I Sun ◽  
M-S Kim
Keyword(s):  
Nasal Cavity ◽  
Rare Case ◽  
Low Grade ◽  
High Grade ◽  
Myoepithelial Carcinoma ◽  
Left Nasal Cavity ◽  
Unique Case ◽  
Medial Maxillectomy ◽  
Epithelial Myoepithelial Carcinoma

AbstractBackground:Epithelial-myoepithelial carcinoma is an uncommon, low-grade carcinoma that generally occurs in the salivary glands. A few cases of epithelial-myoepithelial carcinoma arising in the nasal cavity have been reported. We describe a unique case of aggressive epithelial-myoepithelial carcinoma in the nasal cavity.Case report:A 36-year-old woman presented with a mass in her left nasal cavity. Histopathological evaluation revealed it to be an epithelial-myoepithelial carcinoma with overt nuclear atypia, frequent mitoses and necrosis. The tumour recurred in the contralateral nasal cavity 15 months following primary excision. Medial maxillectomy and radiation therapy were performed. Seven-month follow up revealed extensive bone metastases.Conclusion:We report a rare case of aggressive epithelial-myoepithelial carcinoma in the nasal cavity, with high-grade histology.

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