Solitary Fibrous Tumor of the Orbit With Epithelioid Features

2006 ◽  
Vol 130 (7) ◽  
pp. 1039-1041 ◽  
Author(s):  
Irfan Warraich ◽  
Dale M. Dunn ◽  
Jeffrey W. Oliver
Keyword(s):  
Differential Diagnosis ◽  
Mitotic Activity ◽  
Solitary Fibrous Tumor ◽  
Spindle Cell ◽  
Fibrous Histiocytoma ◽  
Mesenchymal Tumors ◽  
Nuclear Atypia ◽  
Solitary Fibrous Tumors ◽  
Fibrous Tumor ◽  
Extrapleural Solitary Fibrous Tumor

Abstract Extrapleural solitary fibrous tumors have often been confused with other mesenchymal tumors, such as hemangiopericytoma, fibrous histiocytoma, fibrous meningioma, and leiomyoma, because of morphologic similarity and underrecognition, especially if some unusual features are present. Recently, epithelioid solitary fibrous tumor has been reported in the mediastinum. We report a case of solitary fibrous tumor of the orbit with biphasic architecture, including spindle cell and epithelioid components. Both components demonstrated immunohistochemical features of a solitary fibrous tumor. A background of scattered vessels was present. No evidence of significant nuclear atypia or mitotic activity was noted. In this report, we discuss the differential diagnosis of solitary fibrous tumor with unusual epithelioid features. Extrapleural solitary fibrous tumor should be included in the differential diagnosis of tumors of the orbit with a spindle cell appearance even in the presence of some epithelioid morphology.

Solitary Fibrous Tumor of the Prostate

2001 ◽  
Vol 125 (2) ◽  
pp. 274-277
Author(s):  
Michael R. Pins ◽  
Steven C. Campbell ◽  
William B. Laskin ◽  
Karen Steinbronn ◽  
Daniel P. Dalton
Keyword(s):  
Mitotic Activity ◽  
Solitary Fibrous Tumor ◽  
Growth Pattern ◽  
Spindle Cell ◽  
Cytologic Atypia ◽  
Diffuse Growth ◽  
High Mitotic Activity ◽  
Spindle Cell Tumors ◽  
Fibrous Tumor

Abstract We report 2 cases of solitary fibrous tumor of the prostate. Histologically, both tumors demonstrated a multipatterned architecture with varying degrees of collagenization and hemangiopericytoma-like foci, and both were composed of CD34-immunopositive spindled cells that insinuated themselves between strips of collagen. The tumor in case 1 was well circumscribed and showed minimal mitotic activity or pleomorphism, whereas the tumor in case 2 was more cellular, less collagenous, had a more diffuse growth pattern, and exhibited cytologic atypia and high mitotic activity. Prostatic solitary fibrous tumor must be distinguished from other spindle cell tumors reported to occur in the prostate. To our knowledge, these cases represent only the fifth and sixth reported cases of prostatic solitary fibrous tumor.

Solitary Fibrous Tumor of the Parapharyngeal Space: A Case Report and Review of the Literature

1996 ◽  
Vol 75 (10) ◽  
pp. 681-684 ◽  
Author(s):  
Kunal Gangopadhyay ◽  
Khalid Taibah ◽  
M. Babu Manohar ◽  
Hala Kfoury
Keyword(s):  
Case Report ◽  
Head And Neck ◽  
Solitary Fibrous Tumor ◽  
Spindle Cell ◽  
Parapharyngeal Space ◽  
English Literature ◽  
Review Of The Literature ◽  
Solitary Fibrous Tumors ◽  
Rare Location ◽  
Fibrous Tumor

Solitary fibrous tumors are uncommon spindle cell neoplasms generally associated with serosal surfaces, especially the pleura. Recently, these tumors have been documented in a number of extrapleural sites including the head and neck. So far only two cases of parapharyngeal solitary fibrous tumor have been reported in the English literature. Rare location of an uncommon lesion often gives rise to difficulty in diagnosis or to misdiagnosis. In both the previously reported cases, as well as in our case, the diagnosis of solitary fibrous tumor was not made until the excised tumor was subjected to histopathology and immunohistochemistry.

Solitary Fibrous Tumor of the Kidney. A Propos of a Case

2009 ◽  
Vol 76 (2) ◽  
pp. 112-114 ◽  
Author(s):  
M. Marzi ◽  
M. D'Alpaos ◽  
P. Piras ◽  
A. Paiusco ◽  
M.S. Minervini ◽  
...  
Keyword(s):  
Solitary Fibrous Tumor ◽  
Renal Pelvis ◽  
Spindle Cell ◽  
Left Kidney ◽  
Clinical Behavior ◽  
Spindle Cell Neoplasm ◽  
Solitary Fibrous Tumors ◽  
Genital Apparatus ◽  
Cell Neoplasm ◽  
Fibrous Tumor

Solitary Fibrous Tumors (SFT) are rare spindle cell neoplasm that typically originate from the pleura. However, cases of the SFT are described with origin in other organs, including the urinary and genital apparatus. Within the kidney, except from the renal pelvis, only 19 cases of SFT are described and such rarity of localization makes the histogenesis and the prognosis of the tumor rather unknown. We report the case of a 72-year-old lady who attended our Unit for a mass that was clinically palpable at the level of the left hemiabdomen. The tomodensitographic test indicated a 19cm-diameter mass of likely pertinence of the middle bystender of the left kidney. She had undergone left radical nephrectomy. The histological examination highlighted a solitary fibrous tumor (SFT): the presence of hypercellularity, of cellular pleiomorphism and of a high number of mitosis has led to a histological diagnosis of malignancy for the neoplasm analyzed. The SFT are of rare clinical comparison: this does not allow for a deep knowledge of the lesion histogenesis and prognosis; moreover, the clinical behavior should be more precisely defined.

scholarly journals A Rare Case of a Solitary Fibrous Tumor of the Spermatic Cord

2021 ◽  
Vol 2021 ◽  
pp. 1-3
Author(s):  
Moyosore Awobajo ◽  
Stefanie Hettwer ◽  
Sarah Hackman
Keyword(s):  
Solitary Fibrous Tumor ◽  
Spermatic Cord ◽  
Rare Case ◽  
Surgical Excision ◽  
Mesenchymal Tumors ◽  
Solitary Fibrous Tumors ◽  
Important Differential Diagnosis ◽  
History Of ◽  
Scrotal Swelling ◽  
Fibrous Tumor

Solitary fibrous tumors (SFTs) are rare mesenchymal tumors, originally identified in the pleura. Even though they have subsequently been described in several extrapleural sites, the incidence of SFTs in the spermatic cord is particularly rare. Here, we report a case of a 27-year-old male that presented with a 3-year history of left scrotal swelling. Computed tomography (CT) and ultrasound demonstrated multiple solid, hypoechoic well-circumscribed masses that were separate from the testis. Surgical excision of the mass led to pathologic diagnosis of a solitary fibrous tumor involving the spermatic cord. Solitary fibrous tumors, although rare, are an important differential diagnosis for urogenital tumors.

Extrapleural Solitary Fibrous Tumor of the Foot

2015 ◽  
Vol 105 (6) ◽  
pp. 557-559
Author(s):  
Charles A. Kean ◽  
Bridget R. Moore ◽  
Ashley M. Nettles ◽  
Richard P. Bui
Keyword(s):  
Solitary Fibrous Tumor ◽  
Surgical Excision ◽  
Solitary Fibrous Tumors ◽  
Mesenchymal Neoplasms ◽  
Complete Surgical Excision ◽  
Rare Manifestation ◽  
Painless Mass ◽  
Fibrous Tumor ◽  
Extrapleural Solitary Fibrous Tumor ◽  
Male Veteran

Solitary fibrous tumors are uncommon mesenchymal neoplasms that were initially described as pleural tumors, but in recent years, numerous extrapleural sites have been reported. A solitary fibrous tumor is characterized as a circumscribed, painless mass with a patternless growth pattern, positive CD34 spindle-shaped cells, bcl-2, and dense keloidal collagen with areas of hypercellularity and hypocellularity. This case report describes a 55-year-old male veteran who presented with a rare manifestation of an extrapleural solitary fibrous tumor of the medial right hallux. Microscopic and immunohistochemical findings were consistent with the previously documented characteristics of solitary fibrous tumors. Complete surgical excision of the tumor is the treatment of choice.

scholarly journals Solitary Fibrous Tumor of the Sigmoid Colon Masquerading as an Adnexal Neoplasm

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Laura Bratton ◽  
Rabih Salloum ◽  
Wenqing Cao ◽  
Aaron R. Huber
Keyword(s):  
Sigmoid Colon ◽  
Solitary Fibrous Tumor ◽  
High Power ◽  
Spindle Cell ◽  
Cytologic Atypia ◽  
Spindle Cell Neoplasm ◽  
Solitary Fibrous Tumors ◽  
Cell Neoplasm ◽  
Mitotic Figures ◽  
Fibrous Tumor

Solitary fibrous tumor is a rare, benign spindle cell neoplasm that was first described in the thoracic pleura. This tumor is now known to occur at many extrapleural sites. There are established criteria for the diagnosis of malignant solitary fibrous tumor including ≥4 mitotic figures per 10 high-power fields, increased cellularity, cytologic atypia, infiltrative margins, and/or necrosis. Although all solitary fibrous tumors have the potential to recur or metastasize, those with malignant histologic features tend to behave more aggressively. We report a case of solitary fibrous tumor, with malignant histologic features, in a 21-year-old woman which arose from the serosal surface of the sigmoid colon.

Solitary Fibrous Tumor of the Anterior Mediastinum: A Rare Extrapleural Neoplasm

2007 ◽  
Vol 93 (5) ◽  
pp. 508-510 ◽  
Author(s):  
Brian R Gannon ◽  
Carolyn D O'Hara ◽  
Kenneth Reid ◽  
Phillip A Isotalo
Keyword(s):  
Solitary Fibrous Tumor ◽  
Mediastinal Mass ◽  
Spindle Cell ◽  
Sarcomatoid Carcinoma ◽  
Anterior Mediastinal Mass ◽  
Peripheral Nerve Sheath Tumors ◽  
Solitary Fibrous Tumors ◽  
Spindle Cells ◽  
Complete Surgical Excision ◽  
Fibrous Tumor

Solitary fibrous tumors are uncommon spindle cell neoplasms originally thought to be restricted to the pleura. We describe a 62-year-old woman who presented with stridor and an anterior mediastinal mass. At thoracotomy, a 10.5 × 6.5 × 5.5 cm, circumscribed, firm mediastinal mass demonstrated no direct cardiac or pulmonary involvement. The tumor consisted of spindle cells organized in a patternless pattern with collagenous stroma and hemangiopericytoma-like vessels. Spindle cells were immunoreactive for CD34, CD99, desmin, vimentin and bcl-2 protein and a diagnosis of mediastinal solitary fibrous tumor was confirmed. The differential diagnosis of mediastinal solitary fibrous tumors is extensive and includes spindle cell thymoma, sarcomatoid carcinoma, malignant mesothelioma, inflammatory myofibroblastic tumor, peripheral nerve sheath tumors and various sarcomas. Despite their rarity in the mediastinum, solitary fibrous tumors can be recognized by their classic patternless morphology and immunophenotypic pattern. Their accurate classification is important, as solitary fibrous tumors are intermediate (rarely metastasizing) neoplasms that require complete surgical excision and long-term clinical follow-up for optimum therapy.

Intramedullary and extramedullary solitary fibrous tumor of the cervical spine

2004 ◽  
Vol 100 (4) ◽  
pp. 358-363 ◽  
Author(s):  
Robert J. Bohinski ◽  
Ehud Mendel ◽  
Kenneth D. Aldape ◽  
Laurence D. Rhines
Keyword(s):  
Cervical Spine ◽  
Solitary Fibrous Tumor ◽  
Spindle Cell ◽  
Review Of The Literature ◽  
Spinal Neoplasms ◽  
Content Type ◽  
Solitary Fibrous Tumors ◽  
Extramedullary Tumor ◽  
Fibrous Tumor ◽  
Tumor Types

✓ Solitary fibrous tumor is a spindle cell tumor deriving from mesenchymal cells that arises most commonly in the pleura. Only very recently has this tumor been reported in the spine. A solitary fibrous tumor strongly resembles other spindle cell neoplasms of the spine and may be an unrecognized entity if not routinely considered in the differential diagnosis of spinal neoplasms. The authors report an unusual intra- and extramedullary location for a solitary fibrous tumor of the cervical spine. Findings in this case and a comprehensive review of the literature indicate that solitary fibrous tumors can originate from various spinal anatomical substrates and mimic both intra- and extramedullary tumor types.

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