scholarly journals n-Acetylcysteine for prevention of iodinated contrast-induced nephropathy in computed tomography angiography procedures in patients with chronic kidney disease

2012 ◽  
Vol 6 (3) ◽  
pp. 181-189
Author(s):  
Cheng Ye
Keyword(s):  
Computed Tomography ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Computed Tomography Angiography ◽  
Contrast Induced Nephropathy ◽  
Iodinated Contrast

scholarly journals Evaluation of prediction score of contrast-induced nephropathy in inpatients undergone to digital or CT angiography

2020 ◽  
Vol 10 (3) ◽  
pp. 78-84
Author(s):  
Seleno Glauber de Jesus-Silva ◽  
Ana Elisa Chaves ◽  
Caio Augusto Alves Maciel ◽  
Edson Eziel Ferreira Scotini ◽  
Pablo Girardelli Mendonça Mesquita ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Roc Curve ◽  
Computed Tomography Angiography ◽  
Score Test ◽  
Area Under The Curve ◽  
Roc Curve Analysis ◽  
Contrast Induced Nephropathy ◽  
Mean Values ◽  
Iodinated Contrast ◽  
The Mean

Objectives: To assess the incidence of contrast-induced nephropathy (CIN) and determine the Mehran Score's (MS) ability to predict CIN in patients undergoing digital angiography or computed tomography angiography. Methods: 252 medical records of inpatients who underwent DA or CTA over 28 months in a quaternary hospital were reviewed. CIN was defined as serum creatinine> 0.5 mg / dL or > 25% increase in baseline creatinine, 48 h after administration of iodinated contrast. The ROC curve and the area under the curve (AUC) were used as a score test. Results: The majority (159; 63.1%) were male, and the average age was 60.4 years. Anemia, diabetes mellitus, and age > 75 years were the most prevalent factors. The incidence of CIN was 17.8% (n = 45). There was a decrease in the mean values ​​of creatinine pre and post among patients who did not suffer CIN (1.38 ± 1.22 vs 1.19 ± 0.89; t = 3.433; p = 0.0007), while among patients who suffering CIN, the mean increase was 1.03 mg / dL (1.43 ± 1.48 vs 2.46 ± 2.35 mg / dL; t = 5.44; p = 0.117). The ROC curve analysis identified a low correlation between MS and the occurrence of CIN (AUC = 0.506). Conclusion: The incidence of CIN in hospitalized patients undergoing angiography or computed tomography angiography was high. The EM did not allow the prediction of NIC.

scholarly journals Post-Contrast Acute Kidney Injury in Patients with Various Stages of Chronic Kidney Disease—Is Fear Justified?

Toxins ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 395
Author(s):  
Inga Chomicka ◽  
Marlena Kwiatkowska ◽  
Alicja Lesniak ◽  
Jolanta Malyszko
Keyword(s):  
Computed Tomography ◽  
Chronic Kidney Disease ◽  
Acute Kidney Injury ◽  
Kidney Disease ◽  
Kidney Injury ◽  
Creatinine Concentration ◽  
Post Contrast ◽  
Iodinated Contrast ◽  
Contrast Enhanced Ct ◽  
Enhanced Ct

Post-contrast acute kidney injury (PC-AKI) is one of the side effects of iodinated contrast media, including those used in computed tomography. Its incidence seems exaggerated, and thus we decided to try estimate that number and investigate its significance in our clinical practice. We analyzed all computed tomographies performed in our clinic in 2019, including data about the patient and the procedure. In each case, we recorded the parameters of kidney function (serum creatinine concentration and eGFR) in four time intervals: before the test, immediately after the test, 14–28 days after the test, and over 28 days after the test. Patients who did not have a follow-up after computed tomography were excluded. After reviewing 706 CT scans performed in 2019, we included 284 patients undergoing contrast-enhanced CT and 67 non-enhanced CT in the final analysis. On this basis, we created two comparable groups in terms of age, gender, the severity of chronic kidney disease, and the number of comorbidities. We found that AKI was more common in the non-enhanced CT population (25.4% vs. 17.9%). In terms of our experience, it seems that PC-AKI is not a great risk for patients, even those with chronic kidney disease. Consequently, the fear of using contrast agents is not justified.

Contrast-Induced Nephropathy in Patients With Chronic Kidney Disease Undergoing Computed Tomography

2006 ◽  
Vol 41 (11) ◽  
pp. 815-821 ◽  
Author(s):  
Brendan J. Barrett ◽  
Richard W. Katzberg ◽  
Henrik S. Thomsen ◽  
Nan Chen ◽  
Dushyant Sahani ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Contrast Induced Nephropathy

scholarly journals The Use of Imaging Techniques in Chronic Kidney Disease-Mineral and Bone Disorders (CKD-MBD)—A Systematic Review

Diagnostics ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 772
Author(s):  
Ana Pimentel ◽  
Jordi Bover ◽  
Grahame Elder ◽  
Martine Cohen-Solal ◽  
Pablo Antonio Ureña-Torres
Keyword(s):  
Computed Tomography ◽  
Chronic Kidney Disease ◽  
Magnetic Resonance ◽  
Kidney Disease ◽  
Imaging Techniques ◽  
Quantitative Computed Tomography ◽  
Vertebral Fracture Assessment ◽  
Vascular Calcifications ◽  
Ckd Stage

Although frequently silent, mineral and bone disease (MBD) is one of the most precocious complication of chronic kidney disease (CKD) and is omnipresent in patients with CKD stage 5. Its pathophysiology is complex, but basically, disturbances in vitamin D, phosphate, and calcium metabolism lead to a diverse range of clinical manifestations with secondary hyperparathyroidism usually being the most frequent. With the decline in renal function, CKD-MBD may induce microstructural changes in bone, vascular system and soft tissues, which results in macrostructural lesions, such as low bone mineral density (BMD) resulting in skeletal fractures, vascular and soft tissue calcifications. Moreover, low BMD, fractures, and vascular calcifications are linked with increased risk of cardiovascular mortality and all-cause mortality. Therefore, a better characterization of CKD-MBD patterns, beyond biochemical markers, is helpful to adapt therapies and monitor strategies as used in the general population. An in-depth characterization of bone health is required, which includes an evaluation of cortical and trabecular bone structure and density and the degree of bone remodeling through bone biomarkers. Standard radiological imaging is generally used for the diagnosis of fracture or pseudo-fractures, vascular calcifications and other features of CKD-MBD. However, bone fractures can also be diagnosed using computed tomography (CT) scan, magnetic resonance (MR) imaging and vertebral fracture assessment (VFA). Fracture risk can be predicted by bone densitometry using dual-energy X-ray absorptiometry (DXA), quantitative computed tomography (QTC) and peripheral quantitative computed tomography (pQTC), quantitative ultrasound (QUS) and most recently magnetic resonance micro-imaging. Quantitative methods to assess bone consistency and strength complete the study and adjust the clinical management when integrated with clinical factors. The aim of this review is to provide a brief and comprehensive update of imaging techniques available for the diagnosis, prevention, treatment and monitoring of CKD-MBD.

Contrast-Induced Nephropathy in Ischemic Stroke Patients Undergoing Computed Tomography Angiography: CINISter Study

2019 ◽  
Vol 28 (3) ◽  
pp. 649-654 ◽  
Author(s):  
Anthony Shaun Rowe ◽  
Brandon Hawkins ◽  
Leslie A. Hamilton ◽  
Andrew Ferrell ◽  
Jennifer Henry ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Ischemic Stroke ◽  
Computed Tomography Angiography ◽  
Stroke Patients ◽  
Contrast Induced Nephropathy
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