scholarly journals Utility of Sampling Perfection with Application Optimized Contrasts Using Different Flip Angle Evolutions Method in Carotid Artery Plaque Magnetic Resonance Imaging

2012 ◽  
Vol 68 (7) ◽  
pp. 871-879
Author(s):  
Tetsuya Urata ◽  
Hidetaka Yamamoto ◽  
Naoaki Ikuta ◽  
Masato Uchikoshi
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Carotid Artery ◽  
Flip Angle ◽  
Resonance Imaging ◽  
Carotid Artery Plaque

Characterization of Carotid Artery Plaque Components on Magnetic Resonance Imaging Using Signal Intensity of the Phantom as a Reference

2013 ◽  
Vol 20 (12) ◽  
pp. 1551-1556
Author(s):  
Akio Ogura ◽  
Katsumi Hayakawa ◽  
Fumie Maeda ◽  
Mariko Kajihara ◽  
Yasuo Takatsu ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Carotid Artery ◽  
Signal Intensity ◽  
Resonance Imaging ◽  
Carotid Artery Plaque

scholarly journals Development of Molecular Magnetic Resonance Imaging Tools for Risk Stratification of Carotid Atherosclerotic Disease Using Dual-Targeted Microparticles of Iron Oxide

2021 ◽  
Author(s):  
Joyce M. S. Chan ◽  
Park Sung Jin ◽  
Michael Ng ◽  
Joanne Garnell ◽  
Chan Wan Ying ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
High Risk ◽  
Magnetic Resonance ◽  
Carotid Artery ◽  
Risk Stratification ◽  
Stroke Prevention ◽  
Inflammatory Activity ◽  
Resonance Imaging ◽  
Inflammatory Status

AbstractIdentification of patients with high-risk asymptomatic carotid plaques remains a challenging but crucial step in stroke prevention. Inflammation is the key factor that drives plaque instability. Currently, there is no imaging tool in routine clinical practice to assess the inflammatory status within atherosclerotic plaques. We have developed a molecular magnetic resonance imaging (MRI) tool to quantitatively report the inflammatory activity in atherosclerosis using dual-targeted microparticles of iron oxide (DT-MPIO) against P-selectin and VCAM-1 as a smart MRI probe. A periarterial cuff was used to generate plaques with varying degree of phenotypes, inflammation and risk levels at specific locations along the same single carotid artery in an Apolipoprotein-E-deficient mouse model. Using this platform, we demonstrated that in vivo DT-MPIO-enhanced MRI can (i) target high-risk vulnerable plaques, (ii) differentiate the heterogeneity (i.e. high vs intermediate vs low-risk plaques) within the asymptomatic plaque population and (iii) quantitatively report the inflammatory activity of local plaques in carotid artery. This novel molecular MRI tool may allow characterisation of plaque vulnerability and quantitative reporting of inflammatory status in atherosclerosis. This would permit accurate risk stratification by identifying high-risk asymptomatic individual patients for prophylactic carotid intervention, expediting early stroke prevention and paving the way for personalised management of carotid atherosclerotic disease.

Role of magnetic resonance imaging in evaluating sphenoid sinus and internal carotid artery

2009 ◽  
Vol 123 (12) ◽  
pp. 1331-1337 ◽  
Author(s):  
H G Hatipoglu ◽  
M A Cetin ◽  
A Selvi ◽  
E Yuksel
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Carotid Artery ◽  
Internal Carotid Artery ◽  
Sphenoid Sinus ◽  
Carotid Arteries ◽  
Internal Carotid ◽  
Minimal Distance ◽  
Resonance Imaging ◽  
Internal Carotid Arteries

AbstractObjective:This study aimed to determine whether magnetic resonance imaging has a role in the evaluation of the sphenoid sinus and internal carotid artery. In addition, we aimed to establish reference measurements for the minimal distance between the internal carotid arteries.Method:The sphenoid sinuses and neighbouring internal carotid arteries of 90 patients were evaluated using sagittal T1-weighted and axial and coronal T2-weighted magnetic resonance images.Results:Sphenoid sinus pneumatisation was categorised as occipitosphenoidal (0 per cent), conchal (3.3 per cent), presellar (14.4 per cent) or sellar (82.2 per cent). The internal carotid artery protruded into the sphenoid sinus in 32.8 per cent, with a septum in 9.4 per cent. The incidence of sellar-type sphenoid sinus pneumatisation was higher in patients with protrusion of the internal carotid artery into the sphenoid sinus (p < 0.001). The incidence of presellar pneumatisation was higher in patients without internal carotid artery protrusion (p < 0.001). The minimal distance between the internal carotid arteries varied between 9.04 and 24.26 mm (mean, 15.94 mm).Conclusion:Magnetic resonance imaging can provide useful information about the sphenoid sinus and internal carotid artery, prior to endoscopic sphenoidotomy and trans-sphenoidal hypophysectomy.

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