scholarly journals Effectiveness and Safety of Ablative Er:YAG Laser Treatment of External Genital Warts

2020 ◽  
Vol 89 (7-8) ◽  
pp. 357-364
Author(s):  
Urška Bizjak Ogrinc ◽  
Sabina Senčar
Keyword(s):  
Cohort Study ◽  
Adverse Effects ◽  
Laser Treatment ◽  
Retrospective Cohort ◽  
Er:Yag Laser ◽  
Condylomata Acuminata ◽  
Genital Warts ◽  
Safe Procedure ◽  
Complete Clearance ◽  
External Genital Warts

Background: The aim of this study is to evaluate effectiveness and safety of the use of ablative Er:YAG laser for removal of external genital warts (EGW), also called condylomata acuminata (CA).Methods: This is a retrospective cohort study performed at Gynecology Clinic Juna in Ljubljana, Slovenia. All patients older than 18 years that were clinically diagnosed with EGW and were treated with ablative Er:YAG laser between January 2012 and December 2017 were included in the study.Results: A total of 133 female patients (mean age 39.6 ± 12.9 years, range: 19–80) with EGW were eligible to be included in this study. EGW have been present from one to seven months, with a mean presence of 2.1 ± 2.0 months. The majority of the warts were on the labia, major some also on the mons pubis. The size of the lesions was 2–8 mm. The majority of patients, who completed therapy (74 patients out of 116; 64 %) received only one treatment and 82 % of the patients (n = 95) showed complete clearance of the lesions, without recurrence observed to date of analysis. Complete clearance was achieved after an average of 1.33 treatment sessions. Recurrence was reported by 21 patients (18 %). Recorded adverse effects of laser treatment were mild and transient.Conclusion: Er:YAG laser removal of EGW is a simple, quick and safe procedure, particularly suitable for large volume EGW or those that are located in anatomical sites difficult to access by other techniques.

scholarly journals Is open tracheotomy performed by residents in otorhinolaryngology a safe procedure? a retrospective cohort study

2014 ◽  
Vol 272 (6) ◽  
pp. 1483-1489 ◽  
Author(s):  
Francesca Romana Fiorini ◽  
Roberto Santoro ◽  
Alberto Deganello ◽  
Giuditta Mannelli ◽  
Giuseppe Meccariello ◽  
...  
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Safe Procedure

scholarly journals Efficacy of Pneumatic Retinopexy in Treating Rhegmatogenous Retinal Detachment at King Abdullah Medical City in Makkah, Saudi Arabia – A retrospective cohort study

2021 ◽  
Vol 13 (2) ◽  
pp. 51-61
Author(s):  
Ashjan Yousef Bamahfouz ◽  
Serene Jouhargy ◽  
Mohammed Almalki ◽  
Osama Alamri ◽  
Raed Alsulami ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Cohort Study ◽  
Retinal Detachment ◽  
Laser Treatment ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Rhegmatogenous Retinal Detachment ◽  
Pneumatic Retinopexy ◽  
Additional Surgery ◽  
Anatomical Success

Introduction: The aim of this study was to present the clinical presentation and short-term outcomes of uncomplicated rhegmatogenous retinal detachment managed by pneumatic retinopexy at a tertiary eye hospital in western Saudi Arabia. Materials and methods:  This one-armed retrospective cohort study evaluated selected cases of rhegmatogenous retinal detachment managed by pneumatic retinopexy between 2017 and 2018. Data were collected on patient demographics, preoperative ophthalmic assessment, surgical details, follow up at six months postoperatively, complications and the need for additional surgery. Anatomic success was defined as retinal attachment at 6 months and functional success was defined as vision >20/200 at six months postoperatively. The association of lens status and concomitant laser treatment to anatomical success rates were evaluated. Results: The study sample consisted of 15 eyes with rhegmatogenous retinal detachment in the upper quadrant. In 14 cases, C3F8 gas was used. Anatomic and functional success was noted in 73.3% [95% confidence interval (CI) 51.0: 95.7] and 86.7% (95% CI 69.2; 100) of eyes, respectively. The association between anatomical success and lens status was not significant [RR = 4.5 (95% CI 0.6 ; 37.5), P=0.1]. There was no significant association between anatomical success and concomitant laser treatment. [RR = RR = 1.7 (95% CI 0.7 ; 4.0), P=0.2]. A 2nd retinal surgery was not required in 33.3% of eyes (95% CI 9.5 ; 57.2).  Conclusion: If stringent selection criteria are used for managing rhegmatogenous retinal detachment with pneumatic retinopexy,  anatomical and functional success by six months postoperatively is achieved in the majority of cases. Additional surgeries could further improve outcomes.

Evaluation of the adverse effects of biological agents used in the treatment of psoriasis: A multicenter retrospective cohort study

2020 ◽  
Vol 33 (6) ◽  
Author(s):  
Filiz Topaloğlu Demir ◽  
Tuğba Özkök Akbulut ◽  
İlknur Kıvanç Altunay ◽  
Sema Aytekin ◽  
İlteriş Oğuz Topal ◽  
...  
Keyword(s):  
Cohort Study ◽  
Adverse Effects ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Biological Agents

scholarly journals Adverse Effects of Fluoroquinolones: A Retrospective Cohort Study in a South Indian Tertiary Healthcare Facility

Antibiotics ◽  
2019 ◽  
Vol 8 (3) ◽  
pp. 104 ◽  
Author(s):  
Benitta Mathews ◽  
Ashley Ann Thalody ◽  
Sonal Sekhar Miraj ◽  
Vijayanarayana Kunhikatta ◽  
Mahadev Rao ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Adverse Effects ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Healthcare Facility ◽  
Study Cohort ◽  
College Hospital ◽  
Routes Of Administration ◽  
South Indian

The Food and Drug Administration (FDA) safety review revealed that the use of fluoroquinolones (FQs) is linked with disabling and potentially permanent serious adverse effects. These adverse effects compromise the tendons, muscles, joints, nerves, and central nervous system of the human body. The purpose of the study was to investigate the incidence and risk factors for adverse drug reactions (ADRs) caused by FQs in comparison with other antibiotics used. A retrospective cohort study was conducted over seven months in Kasturba Medical College Hospital, Manipal, India. Patients who were prescribed with FQs were selected as the study cohort (SC; n = 482), and those without FQs were the reference cohort (RC; n = 318). The results showed that 8.5% (41) of patients developed ADRs in the SC, whereas 4.1% (13) of patients developed ADRs in the RC. With oral and parenteral routes of administration, almost a similar number of ADRs were observed. Levofloxacin caused the highest number of ADRs reported, especially with the 750-mg dose. Based on a multiple logistic regression model, FQ use (odds ratio (OR): 2.27; 95% confidence interval (CI): 1.18–4.39; p = 0.015) and concomitant steroid use (OR: 3.19; 95% CI: 1.31–7.79; p = 0.011) were identified as independent risk factors for the development of ADRs among antibiotics users, whereas age was found to be protective (OR: 0.98; 95% CI: 0.97–1.00; p = 0.047). The study found a higher incidence of ADRs related to FQs compared to other antibiotics. The study concludes a harmful association between FQ use and the development of ADRs. Moreover, FQs are not safe compared to other antibiotics. Hence, the use of FQs should be limited to the conditions where no other alternatives are available.

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