scholarly journals The prognostic and diagnostic value of tissue inhibitor of metalloproteinases gene family and potential function in gastric cancer

2021 ◽  
Vol 12 (13) ◽  
pp. 4086-4098
Author(s):  
Zhao Li ◽  
Qinwen Jing ◽  
Liucheng Wu ◽  
Jiansi Chen ◽  
Mingwei Huang ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Gene Family ◽  
Potential Function ◽  
Diagnostic Value ◽  
Tissue Inhibitor Of Metalloproteinases ◽  
Tissue Inhibitor

Expression of the tissue inhibitor of metalloproteinases (TIMP) gene family in normal and osteoarthritic joints

1999 ◽  
Vol 18 (5-6) ◽  
pp. 183-191 ◽  
Author(s):  
S. Su ◽  
J. Grover ◽  
P. J. Roughley ◽  
J. A. DiBattista ◽  
J. Martel-Pelletier ◽  
...  
Keyword(s):  
Gene Family ◽  
Tissue Inhibitor Of Metalloproteinases ◽  
Tissue Inhibitor ◽  
Timp Gene

Evaluation of hybrid PET/CT gastrography in gastric cancer

2013 ◽  
Vol 04 (06) ◽  
pp. 253-259
Author(s):  
J. Jeong ◽  
E. Kong ◽  
K. Chun ◽  
B. Jang ◽  
T. Kim ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Regional Lymph Node ◽  
Preoperative Evaluation ◽  
Cancer Staging ◽  
Diagnostic Value ◽  
Endoscopic Biopsy ◽  
Depth Of Invasion ◽  
Contrast Enhanced Ct ◽  
Pet Ct ◽  
Ct Gastrography

Summary Aim: With the recent advances in multidetector-row CT, a fusion of functional PET with three dimensional (3D) CT gastrography may provide enhanced diagnostic capability and help surgeons during preoperative planning. The diagnostic value of hybrid PET/CT gastrography was compared with that of conventional PET/CT alone in gastric cancer staging. Patients, methods: Patients with gastric cancer (n = 101) confirmed by endoscopic biopsy specimens underwent conventional PET/CT and regional PET with contrast enhanced CT, followed by gastrectomy with lymphadenectomy at our institution from November 2007 to November 2008. These images were fused into a hybrid PET/CT gastrography using the cardiac IQ fusion software. Conventional PET/CT and hybrid PET/ CT gastrography were evaluated for staging of gastric cancer. After gastrectomy, these were compared with pathologic reports respectively. Results: Gastric cancer was diagnosed as 50 early gastric cancer (EGC) and 51 advanced gastric cancer (AGC) on pathologic examination. In EGC, hybrid PET/CT gastrography and PET/CT identified 36 (72%) and 7 (14%) tumours, respectively. Hybrid PET/CT gastrography correctly delineated the subtype of 25 EGC. In AGC, all 51 (100%) tumours were identified on the hybrid PET/CT gastrography compared to 39 (76.5%) tumours on PET/CT. Hybrid PET/CT gastrography correctly classified the morphology of 42 AGC using the Bormann classification. Additionally, depth of invasion was correctly presented in 38 of 51 AGC. Hybrid PET/CT gastrography for regional lymph node (LN) metastasis in the EGC and AGC showed the sensitivity of 75% and 83.9%, and specificity 90.5% and 55%, respectively. Conclusion: Hybrid PET/CT gastrography is the more intuitive and comprehensive method for the preoperative evaluation of gastric cancer than conventional PET/CT.

scholarly journals Modulation of translation by the 5' leader sequence of the mRNA encoding murine tissue inhibitor of metalloproteinases.

1990 ◽  
Vol 265 (10) ◽  
pp. 5585-5589
Author(s):  
P Waterhouse ◽  
R Khokha ◽  
D T Denhardt
Keyword(s):  
Leader Sequence ◽  
Tissue Inhibitor Of Metalloproteinases ◽  
Tissue Inhibitor ◽  
Murine Tissue
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