scholarly journals A Rare Case Report on Plummer-Vinson Syndrome with a Complication of Oral Cancer in a South-Asian Woman

2020 ◽  
Vol 14 (1) ◽  
Author(s):  
Ayisha Ayisha ◽  
Sheema Masood Ali
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Iron Deficiency ◽  
Cell Carcinoma ◽  
Iron Deficiency Anemia ◽  
Squamous Cell ◽  
Whole Body ◽  
Deficiency Anemia ◽  
Plummer Vinson Syndrome ◽  
Increased Risk

Plummer-Vinson syndrome (PVS), also called "Paterson-Brown-Kelly syndrome“, is a rare medical syndrome generally affecting middle-aged women. Iron deficiency anemia is the prime etiological factor and other probable factors include malnutrition, genetic predisposition, or autoimmune processes characterized by three distinctive features: iron deficiency anemia, dysphagia, and esophageal web. The dysphagia is generally painless and intermittent or progressive over years, restricted to solids, and associated with weight loss. The exact pathogenesis of PVS is still indistinguishable, but it is interconnected with iron deficiency anemia. Plummer-Vinson syndrome, if left untreated, carries an increased risk of developing squamous cell carcinoma of the upper alimentary tract.In this case report, a 40-year-old female patient presented long-standing dysphagia for months, which progressively developed to postcricoid squamous cell carcinoma by the time she approached to medical treatment. Diagnosis was confirmed through laboratory tests, showing iron deficiency anemia and whole-body positron emission tomography-computed tomography (PET-CT) presenting squamous cell carcinoma in postcricoid region (hypopharynx).

scholarly journals Plummer-Vinson syndrome presenting as squamous cell carcinoma of esophagus

2016 ◽  
Vol 07 (02) ◽  
pp. 071-073 ◽  
Author(s):  
Gandhi Lanke ◽  
Pramoda Koduru ◽  
Manoop S. Bhutani
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Squamous Cell ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Deficiency Anemia ◽  
Plummer Vinson Syndrome ◽  
Increased Risk ◽  
Carcinoma Of Esophagus ◽  
Iron Replacement

AbstractPlummer-Vinson syndrome (PVS) also known as Paterson-Brown-Kelly syndrome is a rare syndrome which comprises iron deficiency anemia, dysphagia, and esophageal webs. The pathogenesis of PVS is not clear. Iron deficiency anemia is essential for diagnosis of PVS. If left untreated, there is an increased risk of developing pharyngeal or esophageal cancer in about 10% of patients. There are no strict guidelines for endoscopic surveillance in patients with PVS. Iron replacement can improve dysphagia and potentially lead to regression of esophageal webs. In this case report, we present a patient who had long-standing dysphagia for years which progressed to squamous cell cancer of esophagus by the time she sought medical treatment.

scholarly journals Giant Squamous Cell Carcinoma on Chronic Lichen Planus on the Ankle - A Case Report and Short Literature Review

2019 ◽  
Vol 7 (18) ◽  
pp. 3061-3063 ◽  
Author(s):  
Uwe Wollina ◽  
Claudia Krönert ◽  
Jacqueline Schönlebe ◽  
Aleksandra Vojvodic ◽  
Torello Lotti
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Literature Review ◽  
Cell Carcinoma ◽  
Lichen Planus ◽  
Squamous Cell ◽  
Caucasian Woman ◽  
Increased Risk ◽  
Life Threatening ◽  
Threatening Situation

BACKGROUND: Cutaneous squamous cell carcinoma (SCC) is the second most common malignancy of skin. Although a major risk factor is a chronic exposure to ultraviolet radiation, preexistent chronic inflammatory disorders may also possess an increased risk for SCC. That is not the case for cutaneous lichen planus in contrast to oral lichen planus and oral SCC.  CASE REPORT: We report the case of an 87-year-old Caucasian woman presenting with a giant verrucous tumour on the left ankle. She suffered from long-standing disseminated lichen planus. Histology confirmed the diagnosis of SCC on partly verrucous lichen planus. The course was complicated due to sepsis. An emergency transfemoral amputation became necessary. The patients survived and could be released into her nursery. A literature review underlined the rarity of SCC on lichen planus of the skin. Most of these rare cases were in patients in their second half of life on the lower legs. Hypertrophic lichen plnaus was overrepresented.   CONCLUSIONS: Although very rare by number, SCC can complicate lichen planus and lead to the life-threatening situation. Atypical verrucous lesions on lichen planus warrant a histologic analysis. Surgery is the treatment of choice for cutaneous SCC.

scholarly journals Iron Deficiency as Cause of Dysphagia and Burning Mouth (Plummer-Vinson or Kelly-Patterson Syndrome): a Case Report

2020 ◽  
Vol 63 (3) ◽  
pp. 128-132
Author(s):  
Vladimíra Radochová ◽  
Radovan Slezák ◽  
Jakub Radocha
Keyword(s):  
Case Report ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Clinical Presentation ◽  
Clinical Syndrome ◽  
Deficiency Anemia ◽  
Plummer Vinson Syndrome ◽  
Burning Mouth

The clinical presentation of iron deficiency can be very heterogeneous, including various oral and other mucosal problems. Here, in this case, we report the patient with burning mouth and dysphagia symptoms where iron deficiency was found to be the underlying cause after several months of investigations. This clinical syndrome is called Plummer-Vinson syndrome. It is sporadic with an incidence less than 0.1% of patients suffering from iron deficiency anemia.

scholarly journals Plummer-Vinson Syndrome: A Case Report

2011 ◽  
Vol 31 (3) ◽  
pp. 254-256
Author(s):  
DS Gedam ◽  
J Mandliya ◽  
M Verma
Keyword(s):  
Case Report ◽  
Iron Deficiency ◽  
Ethnic Group ◽  
Iron Deficiency Anemia ◽  
Deficiency Anemia ◽  
White Female ◽  
Esophageal Web ◽  
Plummer Vinson Syndrome ◽  
Classical Triad

Plummer-Vinson also known as sideropenic dysphagia is a disease that is characterized by classical triad of iron deficiency anemia, dysphagia and esophageal web. It is known to mostly affect white female mainly, but cases have been reported from other ethnic group in the literature. Treatment is very promising especially when it is not associated with carcinoma. DOI: http://dx.doi.org/10.3126/jnps.v31i3.4259 J Nep Paedtr Soc 2011;31(3): 254-256

scholarly journals PLUMMER VINSON SYNDROME - is it common in males?

2015 ◽  
Vol 52 (3) ◽  
pp. 250-252 ◽  
Author(s):  
Satvinder Singh BAKSHI
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Oral Iron ◽  
Deficiency Anemia ◽  
Gastrointestinal Malignancies ◽  
Esophageal Web ◽  
Plummer Vinson Syndrome ◽  
Increased Risk ◽  
Male Patients ◽  
Males And Females

BackgroundPlummer-Vinson syndrome is characterized by a triad of dysphagia, iron deficiency anemia and esophageal web. Most of the patients are middle aged women in the fourth to seventh decade of life.ObjectiveVery few cases of Plummer-Vinson syndrome affecting males have been reported. Here we report a series of male patients found to be suffering from Plummer-Vinson syndrome.MethodsFive males presented to us with dysphagia and fatigue of various durations, from April to August, 2012.ResultsThese patients were found to have iron deficiency anemia and esophageal web on subsequent investigations and were treated successfully with oral iron therapy.ConclusionPlummer-Vinson syndrome is common in both males and females and can be successfully treated with oral iron therapy. The patients have an increased risk of developing gastrointestinal malignancies and should be thoroughly evaluated for the same.

Squamous Cell Carcinoma Arising in the Wall of Epidermoid Cyst of Axilla: A case report

1994 ◽  
Vol 30 (2) ◽  
pp. 309
Author(s):  
Sin Young Cho ◽  
Chul Soon Choi ◽  
Ell Seong Lee ◽  
Hyeun Cha Cho ◽  
Eun Young Kwack ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Epidermoid Cyst

CT Findings of Primary Squamous Cell Carcinoma of the Stomach: A Case Report

2008 ◽  
Vol 59 (1) ◽  
pp. 37
Author(s):  
Kyoung Min Kim ◽  
Chang Hee Lee ◽  
Kyeong Ah Kim ◽  
Cheol Min Park
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Primary Squamous Cell Carcinoma ◽  
Carcinoma Of The Stomach ◽  
Ct Findings
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