scholarly journals Male-predominant galanin mediates androgen-dependent aggressive chases in medaka

eLife ◽  
2020 ◽  
Vol 9 ◽  
Author(s):  
Junpei Yamashita ◽  
Akio Takeuchi ◽  
Kohei Hosono ◽  
Thomas Fleming ◽  
Yoshitaka Nagahama ◽  
...  
Keyword(s):  
Preoptic Area ◽  
Parental Behavior ◽  
Social Behaviors ◽  
Neural Substrates ◽  
Medial Preoptic Area ◽  
Histological Studies ◽  
Functional Differences ◽  
Evolutionarily Conserved

Recent studies in mice demonstrate that a subset of neurons in the medial preoptic area (MPOA) that express galanin play crucial roles in regulating parental behavior in both sexes. However, little information is available on the function of galanin in social behaviors in other species. Here, we report that, in medaka, a subset of MPOA galanin neurons occurred nearly exclusively in males, resulting from testicular androgen stimulation. Galanin-deficient medaka showed a greatly reduced incidence of male–male aggressive chases. Furthermore, while treatment of female medaka with androgen induced male-typical aggressive acts, galanin deficiency in these females attenuated the effect of androgen on chases. Given their male-biased and androgen-dependent nature, the subset of MPOA galanin neurons most likely mediate androgen-dependent male–male chases. Histological studies further suggested that variability in the projection targets of the MPOA galanin neurons may account for the species-dependent functional differences in these evolutionarily conserved neural substrates.

scholarly journals A Scientometric Approach to Review the Role of the Medial Preoptic Area (MPOA) in Parental Behavior

2021 ◽  
Vol 11 (3) ◽  
pp. 393
Author(s):  
Alessandro Carollo ◽  
Jan Paolo Macapinlac Balagtas ◽  
Michelle Jin-Yee Neoh ◽  
Gianluca Esposito
Keyword(s):  
Preoptic Area ◽  
Parental Behavior ◽  
Neural Substrates ◽  
Medial Preoptic Area ◽  
Brain Network ◽  
Scientometric Analysis ◽  
Parental Behaviour ◽  
Scientific Papers ◽  
The Relationship

Research investigating the neural substrates underpinning parental behaviour has recently gained momentum. Particularly, the hypothalamic medial preoptic area (MPOA) has been identified as a crucial region for parenting. The current study conducted a scientometric analysis of publications from 1 January 1972 to 19 January 2021 using CiteSpace software to determine trends in the scientific literature exploring the relationship between MPOA and parental behaviour. In total, 677 scientific papers were analysed, producing a network of 1509 nodes and 5498 links. Four major clusters were identified: “C-Fos Expression”, “Lactating Rat”, “Medial Preoptic Area Interaction” and “Parental Behavior”. Their content suggests an initial trend in which the properties of the MPOA in response to parental behavior were studied, followed by a growing attention towards the presence of a brain network, including the reward circuits, regulating such behavior. Furthermore, while attention was initially directed uniquely to maternal behavior, it has recently been extended to the understanding of paternal behaviors as well. Finally, although the majority of the studies were conducted on rodents, recent publications broaden the implications of previous documents to human parental behavior, giving insight into the mechanisms underlying postpartum depression. Potential directions in future works were also discussed.

scholarly journals A Scientometric Approach to Review the Role of the Medial Preoptic Area (MPOA) in Parental Behavior

2021 ◽  
Author(s):  
Alessandro Carollo ◽  
Jan Paolo Macapinlac Balagtas ◽  
Michelle Jin-Yee Neoh ◽  
Gianluca Esposito
Keyword(s):  
Preoptic Area ◽  
Parental Behavior ◽  
Neural Substrates ◽  
Medial Preoptic Area ◽  
Brain Network ◽  
Scientometric Analysis ◽  
Parental Behaviour ◽  
Scientific Papers ◽  
The Relationship

Research investigating the neural substrates underpinning parental behaviour has recently gained momentum. Particularly, the hypothalamic medial preoptic area (MPOA) has been identified as a crucial region for parenting. The current study conducted a scientometric analysis of publications from 01 January 1972 to 19 January 2021 using CiteSpace software to determine trends in the scientific literature exploring the relationship between MPOA and parental behaviour. In total, 677 scientific papers were analysed, producing a network of 1509 nodes and 5498 links. Four major clusters were identified: "C-Fos Expression'', "Lactating Rat'', "Medial Preoptic Area Interaction'' and "Parental Behavior''. Their content suggests an initial trend in which the properties of the MPOA in response to parental behavior were studied, followed by a growing attention towards the presence of a brain network, including the reward circuits, regulating such behavior. Furthermore, while attention was initially directed uniquely to maternal behavior, it has recently been extended to the understanding of paternal behaviors as well. Finally, although the majority of the studies were conducted on rodents, recent publications broaden the implications of previous documents to human parental behavior, giving insight into the mechanisms underlying postpartum depression. Potential directions in future works were also discussed.

scholarly journals A Scientometric Approach to Review the Role of the Medial Preoptic Area (MPOA) in Parental Behavior

2021 ◽  
Author(s):  
Alessandro Carollo ◽  
Jan Paolo Macapinlac Balagtas ◽  
Michelle Jin-Yee Neoh ◽  
Gianluca Esposito
Keyword(s):  
Preoptic Area ◽  
Parental Behavior ◽  
Neural Substrates ◽  
Medial Preoptic Area ◽  
Brain Network ◽  
Scientometric Analysis ◽  
Parental Behaviour ◽  
Scientific Papers ◽  
The Relationship

Research investigating the neural substrates underpinning parental behaviour has recently gained momentum. Particularly, the hypothalamic medial preoptic area (MPOA) has been identified as a crucial region for parenting and other parent-related behaviour. The current study conducted a scientometric analysis of publications from 01 January 1972 to 19 January 2021 using CiteSpace software to determine trends in the scientific literature exploring the relationship between MPOA and parental behaviour. 677 scientific papers were analysed, producing a network of 1,509 nodes and 5,498 links. Four major clusters were identified: ``C-Fos Expression", ``Lactating Rat", ``Medial Preoptic Area Interaction" and ``Parental Behavior". Their content suggests an initial trend in which the properties of the MPOA in response to parental behavior were studied, followed by a growing attention towards the presence of a brain network, including the reward circuits, regulating such behavior. Furthermore, while attention was initially directed uniquely to maternal behavior, it has recently been extended to the understanding of paternal behaviors as well. Finally, although the majority of the studies were conducted on rodents, recent publications broaden the implications of previous documents to human parental behavior, giving insight into the mechanisms underlying postpartum depression. Potential directions in future works were also discussed.

scholarly journals Effects of Prepubertal or Adult Site-Specific Knockdown of Estrogen Receptor β in the Medial Preoptic Area and Medial Amygdala on Social Behaviors in Male Mice

eNeuro ◽  
2016 ◽  
Vol 3 (2) ◽  
pp. ENEURO.0155-15.2016 ◽  
Author(s):  
Mariko Nakata ◽  
Kazuhiro Sano ◽  
Sergei Musatov ◽  
Naoko Yamaguchi ◽  
Toshiro Sakamoto ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Preoptic Area ◽  
Social Behaviors ◽  
Medial Preoptic Area ◽  
Estrogen Receptor Β ◽  
Medial Amygdala ◽  
Male Mice ◽  
Site Specific

scholarly journals The medial preoptic area and the regulation of parental behavior

2014 ◽  
Vol 30 (5) ◽  
pp. 863-865 ◽  
Author(s):  
Kumi O. Kuroda ◽  
Michael Numan
Keyword(s):  
Preoptic Area ◽  
Parental Behavior ◽  
Medial Preoptic Area

Differential ICP responses elicited by electrical stimulation of medial preoptic area

2000 ◽  
Vol 278 (3) ◽  
pp. H964-H970 ◽  
Author(s):  
Yoshikazu Sato ◽  
George J. Christ
Keyword(s):  
Electrical Stimulation ◽  
Penile Erection ◽  
Preoptic Area ◽  
Striated Muscle ◽  
Medial Preoptic Area ◽  
Male Rats ◽  
Histological Studies ◽  
Cavernous Nerve ◽  
Stimulation Pattern ◽  
Stimulation Of

Recent findings indicate a complex role for the medial preoptic area (MPOA) in modulating penile erection. To further investigate this important area we measured changes in intracavernous pressure (ICP) elicited by electrical stimulation of the MPOA and evaluated the contribution of the cavernous nerve to the ICP responses after bilateral transection of the cavernous nerve (CN). In all experiments electrical stimulation was performed unilaterally in anesthetized male rats. Two distinct patterns of ICP response were seen after electrical stimulation of the MPOA: 1) increases in ICP during electrical stimulation ( pattern 1, n = 10 rats) and 2) increases in ICP after electrical stimulation was terminated ( pattern 2, n = 10 rats). For pattern 1, increases in ICP during stimulation exhibited a stable plateau without contraction of striated penile muscles, and bilateral transection of the CN eliminated the ICP responses. For pattern 2, increases in ICP observed after stimulation were lower, more variable, and accompanied by significant amplitude variations (“peaks”), caused by contraction of striated penile muscles. Bilateral transection of the CN eliminated the pattern 2 ICP response but did not alter striated muscle contraction. Histological studies documented that pattern 1 and pattern 2 responses occurred via electrical stimulation of the anterior and posterior areas of the MPOA, respectively. Thus both responses appear to result from activation of the CN, but the pattern 2 response apparently involves contraction of the striated penile muscles as well.

scholarly journals Medial preoptic area antagonistically mediates stress-induced anxiety and parental behavior

2021 ◽  
Author(s):  
Guang-Wei Zhang ◽  
Li Shen ◽  
Can Tao ◽  
A-Hyun Jung ◽  
Bo Peng ◽  
...  
Keyword(s):  
Preoptic Area ◽  
Parental Behavior ◽  
Medial Preoptic Area
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