scholarly journals Multi-nodular Desmoplastic Medulloblastoma in a Child: A Rare Radiological Physiognomy

2019 ◽  
Vol 7 (1) ◽  
pp. 49
Author(s):  
Songping Zheng ◽  
Seidu A. Richard ◽  
Yiyun Fu ◽  
Yan Ju ◽  
Chao You

Introduction: Nodular desmoplastic variant of medulloblastoma although very common, can present with very challenging radiological feature that mimics others lesions in the inferior and lower vermis in children. We present a case of rare radiological appearance of desmoplastic medullobastoma. Case Presentation: A one year and nine months old male presented with unstable walking and projectile vomiting of two weeks’ duration. He was apparently walking well prior this illness. The vomiting was usually in the morning and associated with headaches. Radiological imaging revealed very unusual masses in the cerebellum vermin region with obvious bilateral ventricular enlargement as well as the third ventricle, indicating hydrocephalus. Surgery was successful carried out and microscopic as well as immunohistochemistry confirmed desmoplastic medullobastoma. Conclusion: Desmoplastic medulloblastoma although not very rare can be very problematic in terms of radiological diagnosis. We are of the option that our imaging finding will throw more light on the radiological features of this tumor.

2020 ◽  
Author(s):  
xiaomei ma ◽  
zhi zhu ◽  
yin wang ◽  
weiqing li

Abstract Background: Chordoid gliomas are rare, low-grade neoplasms of the third ventricle. In the updated 4th edition of the 2016 WHO classification of tumours of the CNS, it described some three less common histological patterns and rare tissue patterns. Case presentation:Here we reported a case with all the uncommon patterns. It was a 52-year-old woman with dizziness and blurred vision. Imaging showed a solid tumor located in the third ventricle with a well-circumscribed border. Histological, almost tumor cells formed into atypical glands with different sizes and irregular shapes in an abundant of solid or loosely collagen matrix. Some tumor cells formed into papillary patterns, micro-papillary patterns. pseudoglandular patterns. Some focal tumor cells were spindle-shape. Only few epithelioid tumor cells formed into clusters and cords embedded into a myxoid stroma like the chordoma. No anaplastic features were identified in any lesion. Immunohistochemically, all the tumor cells were strong reactivity for TTF-1. Some tumor cells strong but focal reactivity for GFAP, NEU-N, and CD34. It showed a recurrent D463H missense mutation in PRKCA. All these findings confirm that the diagnosis was chordoid glioma of the third ventricular. Conclusions: There may be lots of histopathological features in one chordoid glioma case. It maybe suggested that PRKCA D463H mutation and TTF-1 positive may help to diagnose it.


2020 ◽  
Author(s):  
xiaomei ma ◽  
zhi zhu ◽  
yin wang ◽  
weiqing li

Abstract Background: Chordoid gliomas are rare, low-grade neoplasms of the third ventricle. In the updated 4th edition of the 2016 WHO classification of tumours of the CNS, it described some three less common histological patterns and rare tissue patterns. Case presentation:Here we reported a case with all the uncommon patterns. It was a 52-year-old woman with dizziness and blurred vision. Imaging showed a solid tumor located in the third ventricle with a well-circumscribed border. Histological, almost tumor cells formed into atypical glands with different sizes and irregular shapes in an abundant of solid or loosely collagen matrix. Some tumor cells formed into papillary patterns, micro-papillary patterns. pseudoglandular patterns. Some focal tumor cells were spindle-shape. Only few epithelioid tumor cells formed into clusters and cords embedded into a myxoid stroma like the chordoma. No anaplastic features were identified in any lesion. Immunohistochemically, all the tumor cells were strong reactivity for TTF-1. Some tumor cells strong but focal reactivity for GFAP, NEU-N, and CD34. It showed a recurrent D463H missense mutation in PRKCA. All these findings confirm that the diagnosis was chordoid glioma of the third ventricular. Conclusions: There may be lots of histopathological features in one chordoid glioma case. It maybe suggested that PRKCA D463H mutation and TTF-1 positive may help to diagnose it.


1973 ◽  
Vol 38 (1) ◽  
pp. 47-51 ◽  
Author(s):  
Gordon Brocklehurst ◽  
M. Chir.

✓ Four cases of extensive cystic dilatation of the third ventricle associated with agenesis of the corpus callosum are described. This condition is termed “diencephalic cyst”; the clinical and radiological features are described. The embryological development of the diencephalon, the telencephalon, and the corpus callosum are described in relation to this malformation. The associated hydrocephalus is also discussed. The treatment and clinical course of the patients is outlined.


2016 ◽  
Vol 30 (1) ◽  
pp. 62-64 ◽  
Author(s):  
Junya Yamaguchi ◽  
Tadashi Watanabe ◽  
Yuichi Nagata ◽  
Tetuya Nagatani ◽  
Yukio Seki

Slit ventricle syndrome (SVS) is a well-known chronic complication of ventriculoperitoneal shunt (VPS) placement. In this report, we describe a unique anatomical change that we observed on the magnetic resonance (MR) images of the brain acquired from a patient with SVS. The patient was a 40-year-old woman who had undergone VPS placement at 3 months of age. A computed tomography scan of her brain revealed a slit-like ventricle. In addition, an MR image of her brain revealed upward ballooning of the third ventricle floor, which returned to normal after a lumbar puncture. This anatomical change resulted from the pressure gradient between the intra- and extraventricular spaces. We believe our findings will further our understanding of the pathogenesis of SVS. Moreover, we hope our findings will help clinicians to select endoscopic third ventriculostomy as the primary surgical approach in patients with this particular SVS pathogenesis in order to avoid complications.


2020 ◽  
Vol 2 (3(September-December)) ◽  
pp. e572020
Author(s):  
Leopoldo Mandic Ferreira Furtado ◽  
José Aloysio da Costa Val Filho ◽  
François Dantas ◽  
Camila Moura De Sousa

Introduction: The use of neuroendoscopic for the management of myelomeningocele-associated hydrocephalus is still controversial. Anatomic variations and abnormalities of the ventricular system and the confusing topography of the floor of the third ventricle are of utmost importance in this approach.  Case presentation: The present case video displayed a case of a 4-year-old girl with myelomeningocele related hydrocephalus presented with a closure of third ventriculostomy after tethered cord release. Several neuroendoscopic options were depicted such as third ventriculostomy using bipolar diathermia, ventriculocystostomy of a quadrigeminal arachnoid cyst and a choroid plexus cauterization as a strategy to improve the success rate of this procedure and handle the difficulties presented in this form of hydrocephalus. Discussion: This video warned the young neurosurgeons regarding ventricular anatomic challenges presented in this case as well as the need of customization of neuroendoscopic approach. Conclusion: Neuroendoscopic approach is an effective strategy to manage myelomeningocele-associated-hydrocephalus.  


2020 ◽  
Vol 9 (2) ◽  
pp. 94-98
Author(s):  
Kaisar Haroon ◽  
Tania Taher ◽  
Abdullah Alamgir ◽  
Arif Reza ◽  
Sk Sader Hossain

Background: Colloid cyst of the third ventricle is a tumour arising from the roof of the third ventricle at the foramen of Monro. Endoscopic excision of colloid cyst is well established technique. There is less morbidity in comparison to the microsurgical resection. Materials and method: Seven patients with colloid cyst were treated with endoscopic excision. Of these five were males and two were female patients. Age ranged thirty to fifty five years from a period from Jan 2016 to Mar 2019 in NINS&H. Results: Most patients had signs of raised intracranial pressure before surgery. Six patients needed post operative VP shunt. Some patients had contusion of the fornix but did not have any memory impairment. Five patients had remnant but there was no symptoms after surgery. Conclusion: Endoscopic excision of the colloid cyst is a good option. Total removal of the tumour is the goal but little remnant of the tumour attached to the tela choroidae is accepted. One year follow-up showed no recurrence of the cyst. Bang. J Neurosurgery 2020; 9(2): 94-98


2020 ◽  
Author(s):  
Kenichi Oyama ◽  
Toshio Hirohata ◽  
Keisuke Onoda ◽  
Shigeyuki Tahara ◽  
Akira Teramoto ◽  
...  

Author(s):  
N.A. Thomson

In a four year grazing trial with dairy cows the application of 5000 kg lime/ ha (applied in two applications of 2500 kg/ha in winter of the first two years) significantly increased annual pasture production in two of the four years and dairy production in one year. In three of the four years lime significantly increased pasture growth over summer/autumn with concurrent increases in milk production. In the last year of the trial lime had little effect on pasture growth but a relatively large increase in milkfat production resulted. A higher incidence of grass staggers was recorded on the limed farmlets in spring for each of the four years. In the second spring immediately following the second application of lime significant depressions in both pasture and plasma magnesium levels were recorded. By the third spring differences in plasma magnesium levels were negligible but small depressions in herbage magnesium resulting from lime continued to the end of the trial. Lime significantly raised soil pH, Ca and Mg levels but had no effect on either soil K or P. As pH levels of the unlimed paddocks were low (5.2-5.4) in each autumn and soil moisture levels were increased by liming, these factors may suggest possible causes for the seasonality of the pasture response to lime


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