scholarly journals The Effect of Essential Oil on Atopic Dermatitis Model of NC/Nga Mice

2014 ◽  
Vol 16 (3) ◽  
pp. 219-225 ◽  
Author(s):  
Sun Hee Han ◽  
Young Mi Seo
2020 ◽  
Vol 33 (3) ◽  
pp. 82-92
Author(s):  
Kwang Ho Yoo ◽  
Tae Rin Kwon ◽  
Young Un Kim ◽  
Eui Hwa Kim ◽  
Beom Joon Kim

2011 ◽  
Vol 19 (1) ◽  
pp. 102-108 ◽  
Author(s):  
Kung-Woo Nam ◽  
Jae-Kyu Noh ◽  
Su-Kwan Kim ◽  
Sung-Jin Lee ◽  
Kyeong-Ho Kim ◽  
...  

2010 ◽  
Vol 60 (2) ◽  
pp. 122-125 ◽  
Author(s):  
Seong Soo Joo ◽  
Yeong-Min Yoo ◽  
Sang-Hwan Ko ◽  
Wonsil Choi ◽  
Mi-Jin Park ◽  
...  

Antioxidants ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1941
Author(s):  
So-Yeon Kim ◽  
Sang-Deok Han ◽  
Minju Kim ◽  
Tamanna Jahan Mony ◽  
Eun-Seok Lee ◽  
...  

The mechanism of atopic dermatitis (AD) is modulated by the release of cytokines and chemokines through the mitogen-activated protein kinase (MAPK)/nuclear factor-kappa B (NF-κB) signaling pathway. Topical steroids are used to treat AD, but some people need safer anti-inflammatory drugs to avoid side effects. Mentha arvensis has been used as a herbal plant with medicinal properties, but its anti-inflammatory effects have not been elucidated in an AD model. In this study, we investigated the anti-inflammatory effects of M. arvensis essential oil (MAEO) and its underlying molecular mechanism in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages and HaCaT cells (human epidermal keratinocyte). Additionally, we examined the ameliorating effects of the MAEO in a dinitrochlorobenzene (DNCB)-induced murine model of AD. We found, in both RAW 264.7 cells and HaCaT cells, MAEO inhibited LPS-stimulated inflammatory mediators such as nitric oxide (NO) and prostaglandin E2 and proinflammatory cytokines, including IL-1β and IL-6, due to the suppression of COX-2 and iNOS expression. In LPS-stimulated macrophages, we also observed that MAEO inhibited the phosphorylation of ERK and P65. Furthermore, MAEO treatment attenuated AD symptoms, including the dermatitis score, ear thickness, epidermal thickness and infiltration of mast cells, in a DNCB-induced animal model of AD. Overall, our findings suggest that MAEO exerts anti-inflammatory and anti-atopic dermatitis effects via inhibition of the ERK/NF-κB signaling pathway.


KSBB Journal ◽  
2013 ◽  
Vol 28 (2) ◽  
pp. 115-122 ◽  
Author(s):  
Geum-Sook Lim ◽  
Ran Kim ◽  
Hoon Cho ◽  
Young-Sook Moon ◽  
Chang-Nam Choi

1972 ◽  
Vol 105 (3) ◽  
pp. 400-404 ◽  
Author(s):  
H. S. Kaufman
Keyword(s):  

1982 ◽  
Vol 118 (4) ◽  
pp. 244-245 ◽  
Author(s):  
M. Uehara
Keyword(s):  

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