scholarly journals A retrospective study detects a novel variant of porcine epidemic diarrhea virus in England in archived material from the year 2000

PeerJ ◽  
2016 ◽  
Vol 4 ◽  
pp. e2564 ◽  
Author(s):  
Falko Steinbach ◽  
Akbar Dastjerdi ◽  
Julie Peake ◽  
S. Anna La Rocca ◽  
Frank P. Tobin ◽  
...  

Outbreaks of porcine epidemic diarrhea (PED) were first recorded in England in the 1970s and continued to be confirmed until 2002. Retrospective analysis of archived material from one of the last confirmed cases in England in the year 2000 demonstrates the previous existence of a very diverse PED virus strain. Following the outbreaks of PED in North America in 2013, there has been renewed interest in phylogenetic analysis of sequences from PEDV strains worldwide. There is a gap in the available sequence data between the mid 1980s and the mid 2000s. This work is an example of how this gap can be at least partially filled by the examination of archived material.

Viruses ◽  
2013 ◽  
Vol 5 (8) ◽  
pp. 1991-2004 ◽  
Author(s):  
Yufei Tian ◽  
Zhijun Yu ◽  
Kaihui Cheng ◽  
Yuxiu Liu ◽  
Jing Huang ◽  
...  

2013 ◽  
Vol 158 (6) ◽  
pp. 1267-1273 ◽  
Author(s):  
Zhili Li ◽  
Feng Chen ◽  
Yao Yuan ◽  
Xiduo Zeng ◽  
Zhongyan Wei ◽  
...  

2020 ◽  
Author(s):  
Zhige Tian ◽  
Yuexiao Lian ◽  
Xiaoliang Hu ◽  
Yue Shi ◽  
Feng Cong

Abstract Background: Since 2010, variant porcine epidemic diarrhea virus (PEDV) has emerged in several provinces of China. The variant strain causes high mortality of newborn piglets, which has resulted in severe economic losses to the pork breeding industry.Results: A variant PEDV strain, SC-YB73, was isolated and identified in China. Pathological observation showed atrophy of villi and edema in the lamina propria. Sequence analysis indicated that six nucleotides were inserted in the E gene, which was first detected in PEDV strains. Furthermore, fifty nucleotide sites were unique in SC-YB73, when compared with another 28 PEDV strains. Phylogenetic analysis based on the complete genome showed that SC-YB73 was clustered in the variant subgroup GII-a, which is widely prevalent in the pig population in China. Recombination analysis suggested that SC-YB73 originated from the recombination of GDS47, TW/Yunlin550/2018, and COL/Cundinamarca/2014.Conclusion: The present study involved the isolation and genetic characterization of a variant PEDV strain. It will provide essential information for the control of PED outbreaks in China.


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