scholarly journals Definitive Radiotherapy for Locally Advanced Merkel Cell Carcinoma of the Head and Neck Region: A Case Report

Cureus ◽  
2019 ◽  
Author(s):  
Aron Gortman
Keyword(s):  
Case Report ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Merkel Cell Carcinoma ◽  
Locally Advanced ◽  
Neck Region ◽  
Merkel Cell ◽  
Head And Neck Region ◽  
Definitive Radiotherapy

scholarly journals Electrochemotherapy as a new therapeutic strategy in advanced Merkel cell carcinoma of head and neck region

2013 ◽  
Vol 47 (4) ◽  
pp. 366-369 ◽  
Author(s):  
Daniele Scelsi ◽  
Niccolò Mevio ◽  
Giulia Bertino ◽  
Antonio Occhini ◽  
Valeria Brazzelli ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Head And Neck ◽  
Merkel Cell Carcinoma ◽  
Residual Life ◽  
Objective Response ◽  
Locally Advanced ◽  
Basal Layer ◽  
Neck Region ◽  
Merkel Cell ◽  
Head And Neck Region

Abstract Background. Merkel Cell Carcinoma (MCC) is a rare and aggressive tumour, arising from a cutaneous mechanoceptor cell located in the basal layer of epidermis, with poor prognosis. The treatment of choice for the initial stage of the disease is surgery and/or radiotherapy. The treatment of recurrent or advanced disease is still controversial. Case report. We report a case of 84 years old woman with a recurrent MCC of the chin treated with electrochemotherapy (ECT). During the period of 20 months, four sessions of ECT were employed, which resulted in an objective response of the tumour and good quality of residual life. Conclusions. Our case shows the effectiveness of ECT in the treatment of locally advanced MCC of the head and neck region in a patient not suitable for standard therapeutic options.

Merkel cell carcinoma of the pinna

1997 ◽  
Vol 111 (12) ◽  
pp. 1195-1198 ◽  
Author(s):  
B. Skia ◽  
A. Bibas ◽  
S. A. Hickey ◽  
N. G. Ryley
Keyword(s):  
Cell Carcinoma ◽  
Head And Neck ◽  
Merkel Cell Carcinoma ◽  
Neck Region ◽  
Merkel Cell ◽  
Rare Tumour ◽  
Head And Neck Region

AbstractMerkel cell carcinoma is an increasingly recognized tumou r of the skin. The commonest presentation is the head and neck region. Only three cases of this rare tumour have been reporte d on the pinna. A further such case is presented here.

scholarly journals Giant locally advanced and metastatic squamous cell skin carcinoma of head and neck region: case report

2020 ◽  
Vol 25 (1) ◽  
pp. 20-22
Author(s):  
Jan Stuk ◽  
Jaroslav Vanasek ◽  
Karel Odrazka ◽  
Martin Dolezel ◽  
Iveta Kolarova ◽  
...  
Keyword(s):  
Case Report ◽  
Head And Neck ◽  
Squamous Cell ◽  
Locally Advanced ◽  
Neck Region ◽  
Skin Carcinoma ◽  
Head And Neck Region ◽  
Squamous Cell Skin Carcinoma

Hypopharyngeal Squamous Cell Carcinoma and Laryngeal Neuroendocrine Carcinoma Colliding in the Aryepiglottic Fold: A Case Report

2017 ◽  
Vol 103 (1_suppl) ◽  
pp. S1-S4 ◽  
Author(s):  
Roberta Marangoni ◽  
Simone Mauramati ◽  
Giulia Bertino ◽  
Antonio Occhini ◽  
Marco Benazzo ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Neuroendocrine Carcinoma ◽  
Squamous Cell ◽  
Neck Region ◽  
Collision Tumor ◽  
Small Cell ◽  
Head And Neck Region

Purpose A collision tumor consists of 2 different histologically distinct and topographically independent tumors merging in the same mass. In the head and neck region they are rare, with only 4 cases reported in the larynx. Case report A 60-year-old heavy smoker complained of a left submandibular lesion in October 2014. The lesion was excised and showed a poorly differentiated carcinoma, suggestive for adenocarcinoma. After a positron emission tomography-computed tomography scan showed increased metabolic activity in the left laterocervical region and right vocal cord, the patient underwent endoscopic biopsy of the lesion of the left piriform sinus, which was positive for moderately differentiated squamous cell carcinoma (SCC). He was then submitted to circular pharyngolaryngectomy, reconstruction with a radial forearm free flap, and bilateral neck dissection. The histopathologic examination showed an in situ and microinvasive SCC of the left pyriform sinus colliding with a high-grade, non-small-cell neuroendocrine carcinoma of the larynx. Conclusions To our knowledge, this is the first case described of laryngeal collision tumor comprising a neuroendocrine component. The choice of treatment of this kind of lesion is difficult because of the presence of 2 different histologies and of the controversial prognostic correlation of non-small-cell neuroendocrine neoplasms of the head and neck region.

scholarly journals Secondary Merkel Cell Carcinoma Manifested in the Parotid

2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
M. Basati ◽  
K. Kassam ◽  
A. Messiha
Keyword(s):  
Cell Carcinoma ◽  
Head And Neck ◽  
Merkel Cell Carcinoma ◽  
Maxillofacial Surgery ◽  
Neck Region ◽  
Surgical Excision ◽  
Malignant Tumour ◽  
Selective Neck Dissection ◽  
Merkel Cell

Background. Merkel cell carcinoma of the head and neck is a rare and aggressive malignant tumour. Both the dermatological and surgical colleagues should be aware of this entity as lesions usually present on sun exposed areas of the skin such as the head and neck.Main Observation and Treatment. A 69-year-old male originally presented to the maxillofacial surgery department with a growing lesion on the left eyebrow. Histological analysis confirmed Merkel cell carcinoma and consequently surgical excision was carried out. A follow-up PET/CT scan 2 years later demonstrated a hotspot in the left parotid gland. Fine needle aspiration and cytology revealed Merkel cell carcinoma. A subtotal parotidectomy left side with ipsilateral selective neck dissection levels I to III was carried out.Conclusions. Potential secondary Merkel cell carcinoma in the head and neck region should be taken into account when planning short- and long-term follow up for previously diagnosed patients. This followup should involve both dermatological and surgical colleagues.

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