A SEER analysis of survival and prognostic factors in merkel cell carcinoma of the head and neck region

2021 ◽  
Author(s):  
C.C. Go ◽  
D.H. Kim ◽  
C.A. Briceño
Keyword(s):  
Prognostic Factors ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Merkel Cell Carcinoma ◽  
Neck Region ◽  
Merkel Cell ◽  
Head And Neck Region

scholarly journals Electrochemotherapy as a new therapeutic strategy in advanced Merkel cell carcinoma of head and neck region

2013 ◽  
Vol 47 (4) ◽  
pp. 366-369 ◽  
Author(s):  
Daniele Scelsi ◽  
Niccolò Mevio ◽  
Giulia Bertino ◽  
Antonio Occhini ◽  
Valeria Brazzelli ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Head And Neck ◽  
Merkel Cell Carcinoma ◽  
Residual Life ◽  
Objective Response ◽  
Locally Advanced ◽  
Basal Layer ◽  
Neck Region ◽  
Merkel Cell ◽  
Head And Neck Region

Abstract Background. Merkel Cell Carcinoma (MCC) is a rare and aggressive tumour, arising from a cutaneous mechanoceptor cell located in the basal layer of epidermis, with poor prognosis. The treatment of choice for the initial stage of the disease is surgery and/or radiotherapy. The treatment of recurrent or advanced disease is still controversial. Case report. We report a case of 84 years old woman with a recurrent MCC of the chin treated with electrochemotherapy (ECT). During the period of 20 months, four sessions of ECT were employed, which resulted in an objective response of the tumour and good quality of residual life. Conclusions. Our case shows the effectiveness of ECT in the treatment of locally advanced MCC of the head and neck region in a patient not suitable for standard therapeutic options.

Merkel cell carcinoma of the pinna

1997 ◽  
Vol 111 (12) ◽  
pp. 1195-1198 ◽  
Author(s):  
B. Skia ◽  
A. Bibas ◽  
S. A. Hickey ◽  
N. G. Ryley
Keyword(s):  
Cell Carcinoma ◽  
Head And Neck ◽  
Merkel Cell Carcinoma ◽  
Neck Region ◽  
Merkel Cell ◽  
Rare Tumour ◽  
Head And Neck Region

AbstractMerkel cell carcinoma is an increasingly recognized tumou r of the skin. The commonest presentation is the head and neck region. Only three cases of this rare tumour have been reporte d on the pinna. A further such case is presented here.

scholarly journals Secondary Merkel Cell Carcinoma Manifested in the Parotid

2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
M. Basati ◽  
K. Kassam ◽  
A. Messiha
Keyword(s):  
Cell Carcinoma ◽  
Head And Neck ◽  
Merkel Cell Carcinoma ◽  
Maxillofacial Surgery ◽  
Neck Region ◽  
Surgical Excision ◽  
Malignant Tumour ◽  
Selective Neck Dissection ◽  
Merkel Cell

Background. Merkel cell carcinoma of the head and neck is a rare and aggressive malignant tumour. Both the dermatological and surgical colleagues should be aware of this entity as lesions usually present on sun exposed areas of the skin such as the head and neck.Main Observation and Treatment. A 69-year-old male originally presented to the maxillofacial surgery department with a growing lesion on the left eyebrow. Histological analysis confirmed Merkel cell carcinoma and consequently surgical excision was carried out. A follow-up PET/CT scan 2 years later demonstrated a hotspot in the left parotid gland. Fine needle aspiration and cytology revealed Merkel cell carcinoma. A subtotal parotidectomy left side with ipsilateral selective neck dissection levels I to III was carried out.Conclusions. Potential secondary Merkel cell carcinoma in the head and neck region should be taken into account when planning short- and long-term follow up for previously diagnosed patients. This followup should involve both dermatological and surgical colleagues.

scholarly journals The Evolution of Care of Cancers of the Head and Neck Region: State of the Science in 2020

Cancers ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1543
Author(s):  
Flora Yan ◽  
Hannah M. Knochelmann ◽  
Patrick F. Morgan ◽  
John M. Kaczmar ◽  
David M. Neskey ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Cancer Care ◽  
Neck Region ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Merkel Cell ◽  
Head And Neck Region

Cancers that arise in the head and neck region are comprised of a heterogeneous group of malignancies that include carcinogen- and human papillomavirus (HPV)-driven mucosal squamous cell carcinoma as well as skin cancers such as cutaneous squamous cell carcinoma, basal cell carcinoma, melanoma, and Merkel cell carcinoma. These malignancies develop in critical areas for eating, talking, and breathing and are associated with substantial morbidity and mortality despite advances in treatment. Understanding of advances in the management of these various cancers is important for all multidisciplinary providers who care for patients across the cancer care continuum. Additionally, the recent Coronavirus Disease 2019 (COVID-19) pandemic has necessitated adaptations to head and neck cancer care to accommodate the mitigation of COVID-19 risk and ensure timely treatment. This review explores advances in diagnostic criteria, prognostic factors, and management for subsites including head and neck squamous cell carcinoma and the various forms of skin cancer (basal cell carcinoma, cutaneous squamous cell carcinoma, Merkel cell carcinoma, and melanoma). Then, this review summarizes emerging developments in immunotherapy, radiation therapy, cancer survivorship, and the delivery of care during the COVID-19 era.

scholarly journals Vulvar Merkel Cell Carcinoma: A Rare Entity

2011 ◽  
Vol 3 (3) ◽  
pp. 145-146
Author(s):  
Monica Soni ◽  
Sudesh Aggarwal ◽  
Prasoon Soni ◽  
Puja Gupta ◽  
Shaifali Dadhich ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Neck Region ◽  
Small Cell ◽  
Rare Entity ◽  
Merkel Cell ◽  
Head And Neck Region ◽  
Vulvar Tumor ◽  
Trabecular Carcinoma

ABSTRACT Merkel cell carcinoma is a primary small cell carcinoma of the skin that resembles oat cell carcinomas of the lung. This tumor has a predilection for head and neck region but may rarely occur as isolated vulvar tumor. It has aggressive malignant behavior and should not be missed while evaluating vulvar masses. We report a case of 45-year-old Mrs I, who presented with recurrent vulvar swelling and was diagnosed as stage III Merkel cell carcinoma of the vulva. Synonyms Primary neuroendocrine carcinoma, Trabecular carcinoma, Primary small cell carcinoma, Cutaneous apudoma.

Mucosal Adenoid Squamous Cell Carcinoma of the Head and Neck

1996 ◽  
Vol 105 (5) ◽  
pp. 409-413 ◽  
Author(s):  
Alfio Ferlito ◽  
Kenneth O. Devaney ◽  
Christopher M. Milroy ◽  
Alessandra Rinaldo ◽  
Antonino Carbone
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Adenosquamous Carcinoma ◽  
Neck Region ◽  
Metastatic Adenocarcinoma ◽  
Head And Neck Region ◽  
Adenoid Cystic ◽  
Basaloid Squamous

Adenoid squamous cell carcinoma is an uncommon variant of squamous cell carcinoma. The lesion is histologically distinctive and it is usually localized on the skin of the head and neck region; it only rarely involves the mucosal sites. The differential diagnoses include adenosquamous carcinoma, adenoid cystic carcinoma, mucoepidermoid carcinoma, basaloid squamous cell carcinoma, and metastatic adenocarcinoma. Surgery is the treatment of choice. The biologic behavior of this neoplasm is more aggressive when it involves mucosal areas, and the prognosis seems worse than that of conventional squamous cell carcinoma.

scholarly journals Role of Sentinel Lymph Node Biopsy in the Management of Merkel Cell Carcinoma

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Eric P. Arruda ◽  
Kevin M. Higgins
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Neck Region ◽  
Lymph Node Biopsy ◽  
Merkel Cell ◽  
Treatment Protocols ◽  
Node Biopsy

Merkel cell carcinoma (MCC) is a rare and typically aggressive form of skin cancer. It most commonly affects the elderly and has a predilection for the sun-exposed skin of the head and neck region. Other etiological factors include immune suppression, organ transplantation, and polyoma virus infection. MCC has a propensity to spread to regional lymphatics with a high locoregional recurrence rate. Since its discovery in 1972, treatment paradigms have shifted, with no consensus on optimal management strategies. Currently, standard of care includes surgical intervention to the primary and locoregional site with adjuvant radiotherapy for high-risk disease. In this paper, we discuss the history, pathology, and epidemiology of this rare disease with a focus on the evidentiary basis of treatment protocols. The use of sentinel lymph node biopsy as a management option will be the focus of this paper.

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