scholarly journals The Effect of Omega-3 Fatty Acids Supplementation on the Improvement of Metabolic Syndrome in Patients with Ischemic Heart Disease: A Double-blind, Randomised, Placebo-controlled Trial

2020 ◽  
Author(s):  
Asma Zamanian ◽  
Rasoul Zarrin ◽  
Samira Faraji ◽  
Parvin Ayramloy ◽  
Behzad Rahimi Darabad
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Fatty Acids ◽  
Placebo Group ◽  
Controlled Trial ◽  
Density Lipoprotein ◽  
Cardiac Ischemia ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Double Blind

Introduction: Metabolic syndrome is a set of metabolic abnormalities that increase the risk of cardiovascular disease. Omega-3 fatty acids may play a role in improving metabolic syndrome by affecting endothelial status. Aim: To study the effect of omega-3 fatty acids on metabolic syndrome in patients with cardiac ischemia. Materials and Methods: This was a 12-weeks, double-blind, randomised, placebo-controlled trial. Ninety patients with a history of cardiac ischemia and metabolic syndrome were randomly divided into intervention (n=45) and placebo (n=45) groups. In the end, 86 people completed the study. The intervention group consumed daily Omega-3 capsules containing 1000 mg fish oil, 180 mg EPA and 120 mg DHA. The placebo group took gelatin-containing capsules. Serum triglycerides, Fasting Blood Sugar (FBS), cholesterol, Low-Density Lipoprotein (LDL), High-Density Lipoprotein (HDL) were measured at baseline and the end of the study and weight, waist circumference, Body Mass Index (BMI) were measured at baseline, middle and end of the study. Independent t-test was used for comparing the baseline and mean changes. The variables that measured in three times were compared using repeated measurement test between two groups. Paired t-test was performed to compare within group differences. Results: Serum triglyceride, FBS, weight and systolic blood pressure decreased and serum HDL increased compared to the placebo group. There were no significant changes in serum cholesterol, LDL, BMI, waist circumference and diastolic blood pressure after omega-3 administration. Conclusion: Omega-3 supplementation for 12 weeks improves some of the indicators of metabolic syndrome in individuals with ischemic heart disease. (IRCT Code: IRCT20190819044563N1).

scholarly journals Effects of exergame training combined with omega-3 fatty acids on the elderly brain: a randomized double-blind placebo-controlled trial

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Alexandra Schättin ◽  
Corinne Baier ◽  
Domenique Mai ◽  
Verena Klamroth-Marganska ◽  
Isabelle Herter-Aeberli ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Controlled Trial ◽  
The Elderly ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Double Blind ◽  
Double Blind Placebo

scholarly journals A randomised, double-blind, placebo-controlled trial of minocycline and/or omega-3 fatty acids added to treatment as usual for at-risk mental states (NAYAB): study protocol

Trials ◽  
2017 ◽  
Vol 18 (1) ◽  
Author(s):  
Inti Qurashi ◽  
Imran B. Chaudhry ◽  
Ameer B. Khoso ◽  
Sana Farooque ◽  
Steve Lane ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Study Protocol ◽  
Controlled Trial ◽  
Mental States ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Double Blind ◽  
Treatment As Usual ◽  
Double Blind Placebo ◽  
At Risk Mental States

scholarly journals Effect of fish oil omega-3 fatty acids on reduction of depressive symptoms among HIV-seropositive pregnant women: a randomized, double-blind controlled trial

2018 ◽  
Vol 17 (1) ◽  
Author(s):  
Rose Okoyo Opiyo ◽  
Peter Suwirakwenda Nyasulu ◽  
Reuben Kamau Koigi ◽  
Anne Obondo ◽  
Dorington Ogoyi ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Depressive Symptoms ◽  
Fish Oil ◽  
Pregnant Women ◽  
Controlled Trial ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Double Blind ◽  
Hiv Seropositive

P193b A DOUBLE BLIND RANDOMIZED CONTROLLED TRIAL ON ORAL NUTRITIONAL SUPPLEMENTATION OF OMEGA-3 FATTY ACIDS IN NON-SMALL CELL LUNG CARCINOMA

2008 ◽  
Vol 3 ◽  
pp. 111
Author(s):  
B.S. van der Meij ◽  
J.A. Languis ◽  
V. van Adrichem ◽  
M.D. Spreeuwenberg ◽  
E.F. Smit ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Small Cell Lung Carcinoma ◽  
Controlled Trial ◽  
Small Cell ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Small Cell Lung ◽  
Double Blind ◽  
Cell Lung Carcinoma ◽  
Randomized Controlled

scholarly journals The intake assessment of diverse dietary patterns on childhood hypertension: alleviating the blood pressure and lipidemic factors with low-sodium seafood rich in omega-3 fatty acids

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Anahita Izadi ◽  
Leila Khedmat ◽  
Reza Tavakolizadeh ◽  
Sayed Yousef Mojtahedi
Keyword(s):  
Blood Pressure ◽  
Fatty Acids ◽  
Dietary Diversity ◽  
Density Lipoprotein ◽  
Second Phase ◽  
Inverse Association ◽  
Cumulative Number ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Childhood Hypertension

Abstract Background Childhood hypertension (CH) is related to the dietary intake and diversity of children. The study aimed to assess the critical role of dietary diversity, and seafood long-chain n-3 polyunsaturated fatty acids (LC n-3 PUFAs) in reducing CH among the Iranian community. Methods A cross-sectional two-phase study with 7–12-year-old Iranian students was designed. In the initial phase, the socio-demographic characteristics, and blood pressure status (normal, pre-hypertension, and hypertension) based on systolic (SBP) and diastolic (DBP) blood pressure data were assessed. The 24-h dietary recall questionnaire was used to generate the dietary diversity score (DDS, count of consumed food groups) and dietary variety score (DVS, the cumulative number of daily consumed food items). In the second phase, the association between CH reduction and changes in serum 25-hydroxyvitamin D (25OHD), total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), and triglycerides (TG) levels of schoolchildren intervened by a seafood diet rich in omega-3 fatty acids were assessed using the regression analyses. Results The pre-hypertension and hypertension prevalence rates were 7.8 and 9.15%, respectively. CH was significantly associated with age, gender, and DDS. A significant inverse association was found between the high intake of seafood and CH (P = 0.032). The gas-chromatography analysis showed the high presence of α-linolenic (ALA, 6.72%), eicosapentaenoic (EPA, 7.62%), docosapentaenoic (DPA, 5.88%), and docosahexaenoic (DHA, 18.52%) acids in the seafood-based diet (p <  0.05). The low blood pressure levels with regular consumption of this healthy-functional diet were significantly associated with a reduction in BMI, LDL, TC, and TG, and a remarkable increase in 25OHD and HDL levels. The multiple linear regression showed that the SBP was highly associated with the TC (p <  0.001; β = 0.464). Conclusions The age and DDS were efficient predictors for the different CH status. A regular seafood-rich dietary pattern due to the high LC n-3 PUFAs contents could significantly reduce the obesity-related cardiovascular risk factors.

scholarly journals Effects of prescription niacin and omega-3 fatty acids on lipids and vascular function in metabolic syndrome: a randomized controlled trial

2012 ◽  
Vol 53 (11) ◽  
pp. 2429-2435 ◽  
Author(s):  
Gregory C. Shearer ◽  
James V. Pottala ◽  
Susan N. Hansen ◽  
Verdayne Brandenburg ◽  
William S. Harris
Keyword(s):  
Metabolic Syndrome ◽  
Fatty Acids ◽  
Randomized Controlled Trial ◽  
Vascular Function ◽  
Controlled Trial ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Randomized Controlled

scholarly journals Omega-3 fatty acids are protective against paclitaxel-induced peripheral neuropathy: A randomized double-blind placebo controlled trial

BMC Cancer ◽  
2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Zohreh Ghoreishi ◽  
Ali Esfahani ◽  
Abolghasem Djazayeri ◽  
Mahmoud Djalali ◽  
Banafsheh Golestan ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Peripheral Neuropathy ◽  
Controlled Trial ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Double Blind ◽  
Double Blind Placebo

scholarly journals Intravenous omega-3 fatty acids are associated with better clinical outcome and less inflammation in patients with predicted severe acute pancreatitis: A randomised double blind controlled trial

2020 ◽  
Vol 39 (9) ◽  
pp. 2711-2719 ◽  
Author(s):  
D. Al-Leswas ◽  
A.M. Eltweri ◽  
W.-Y. Chung ◽  
A. Arshad ◽  
J.A. Stephenson ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Acute Pancreatitis ◽  
Clinical Outcome ◽  
Severe Acute Pancreatitis ◽  
Controlled Trial ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Double Blind
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