scholarly journals The Effect of the Thyrotropin Releasing Hormone (TRH) on the Motor Speech Disorder in Spinocerebellar Degeneration

1992 ◽  
Vol 14 (2) ◽  
pp. 173-183
Author(s):  
Yasuo NOZAKI ◽  
Masahiro HASHIMOTO ◽  
Akio OHNISHI ◽  
Yoshiyuki MURAI ◽  
Hajime OGATA ◽  
...  
Keyword(s):  
Speech Disorder ◽  
Thyrotropin Releasing Hormone ◽  
Spinocerebellar Degeneration ◽  
Motor Speech ◽  
Releasing Hormone ◽  
Motor Speech Disorder

10-Effects of non-invasive brain stimulation on motor speech disorder in Parkinson’s disease

2018 ◽  
Vol 129 (4) ◽  
pp. e9
Author(s):  
L. Brabenec ◽  
J. Mekyska ◽  
Z. Galáž ◽  
P. Klobušiakova ◽  
M. Koštálová ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Brain Stimulation ◽  
Speech Disorder ◽  
Motor Speech ◽  
Non Invasive ◽  
Motor Speech Disorder

scholarly journals Childhood Apraxia of Speech. Developmental Speech Patterns. A Wide Retrospective Study

2020 ◽  
Vol 11 (3sup1) ◽  
pp. 54-68
Author(s):  
Elad Vashdi ◽  
◽  
Amit Avramov ◽  
Špela Falatov ◽  
Huang Yi-Chen ◽  
...  
Keyword(s):  
Factor Analysis ◽  
Exploratory Factor Analysis ◽  
Sound Production ◽  
Speech Disorder ◽  
Apraxia Of Speech ◽  
Childhood Apraxia Of Speech ◽  
Motor Speech ◽  
Entry Level ◽  
Motor Speech Disorder ◽  
Speech Patterns

Patterns of a phenomenon define the entity. If one understands the patterns of the maze, he can find his way there. Patterns of colors on a dress will hold its characters and soul. Understanding the expressive patterns of a developmental syndrome enables treating it with success. It is true for treating Childhood Apraxia of speech (CAS) as well. CAS as motor-speech disorder involves difficulties in sounds production for speech purposes. The difficulties can be demonstrated in patterns that would be specific to CAS. These patterns can distinguish one phenomenon from another. A retrospective research was conducted based on 277 entry level evaluations of children diagnosed with CAS or suspected of CAS who visited a private clinic between 2006 and 2013. The analysis included speech variables alongside background and environmental variables. This article is dealing with speech patterns of children with motor speech disorder. Among the patterns examined are vowels ladder, single syllable ladder, Blowing and SSP (single sound production), Oral motor and SSP, Consonant group ladder and Consonants Exploratory factor analysis. The findings demonstrated the relationship and order of vowels, consonants and single syllables among Hebrew speaking children diagnosed with motor speech disorder. The Consonants Exploratory factor analysis gave validity to the existence of unique consonant groups. Further discussion regarding every result and its implication is included. Understanding the unique patterns of consonants and vowels strength among children with CAS can help clinicians in the decision-making process and goals targeting.

Speak App: A Development of Mobile Application Guide for Filipino People with Motor Speech Disorder

2018 ◽  
Author(s):  
Marilou N. Jamis ◽  
Emeliza R. Yabut ◽  
Rosauro E. Manuel ◽  
Annaliza E. Catacutan-Bangit
Keyword(s):  
Mobile Application ◽  
Speech Disorder ◽  
Motor Speech ◽  
Motor Speech Disorder ◽  
Filipino People

scholarly journals Attention/Memory Impairment is Correlated with Motor Speech Disorder in Parkinson’s Disease

2019 ◽  
Author(s):  
Ying Liu ◽  
Yuchang Gui ◽  
Jincui Hu ◽  
Shanshan Liang ◽  
Sixia Mo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Educational Level ◽  
Cognitive Intervention ◽  
Speech Disorder ◽  
Motor Speech ◽  
Motor Speech Disorder ◽  
Independent Risk Factors ◽  
Attention Memory

Abstract Background The mechanisms underlying the online modulation of motor speech in Parkinson’s disease (PD) have not been determined. Moreover, medical and rehabilitation interventions for PD-associated motor speech disorder (MSD) have a poor long-term prognosis. Methods To compare risk factors in PD patients with MSD to those without MSD (non-MSD) and determine predictive independent risk factors correlated with the MSD phenotype, we enrolled 314 PD patients, including 250 with and 64 without MSD. We compared demographic, characteristic data, as well as PD-associated evaluations between the MSD group and non-MSD group. Results Univariate analysis showed that demographic characteristics, including occupation, educational level, monthly income and speaking background; clinical characteristics, including lesions in the frontal and temporal lobes, and concurrent dysphagia; and PD-associated evaluations, including the activity of daily living (ADL) score, non-motor symptoms scale (NMSS) domain 4 score (perceptual problem), and NMSS domain 5 score (attention/memory) were all significantly different between the MSD and non-MSD group (all P < 0.05). Multivariate logistic regression analysis showed that educational level, frontal lesions, and NMSS domain 5 score (attention/memory) were independent risk factors for PD-associated MSD (all P < 0.005). Conclusions We determined an association between MSD phenotype and cognitive impairment, reflected by low-level education and related clinical profiles. Moreover, attention and memory dysfunction may play key roles in the progression of MSD in PD patients. Further studies are required to detail the mechanism underlying abnormal speech motor modulation in PD patients. Early cognitive intervention may enhance rehabilitation management and motor speech function in patients with PD-associated MSD.

scholarly journals PET Study in a Patient with Spinocerebellar Degeneration before and after Long-Term Administration of Thyrotropin Releasing Hormone

1996 ◽  
Vol 9 (3-4) ◽  
pp. 171-175
Author(s):  
H. Tanji ◽  
H. Nagasawa ◽  
T. Hayashi ◽  
H. Onodera ◽  
T. Fujiwara ◽  
...  
Keyword(s):  
Thyrotropin Releasing Hormone ◽  
Spinocerebellar Degeneration ◽  
Chronic Effect ◽  
Releasing Hormone ◽  
Positron Emission ◽  
Significant Difference ◽  
Before And After ◽  
Term Administration ◽  
The Central Nervous System

We studied the chronic effect of thyrotropin releasing hormone (TRH) in a patient with spinocerebellar degeneration by measuring cerebral metabolic rate for glucose (CMRG1c) using 2-[18F]fluoro-2-deoxy-D-glucose (18FDG) and positron emission tomography (PET). A 56-year-old female, who had suffered from progressive ataxia for 2 years, was treated by intravenous administration of 2 mg TRH for 3 weeks, and CMRG1c of the brain was measured before and after treatment. CMRG1c was markedly decreased in the cerebellum and there was no significant difference before and after the treatment, i.e. mean CMRG1c values were 4.92 and 4.90 mg/100 g/min, and the ratios of the cerebellum versus the frontal cortex were 0.50 and 0.51, respectively. The degree of disequilibrium of her body examined with stabilography became better by the 19th day and further improved by the 26th day after the start of TRH treatment. Based on the present study we conclude that long-term administration of TRH did not improve CMRG1c in the cerebellum, but evidently improved the sway of gravity center by stabilography. We speculate that the chronic effect of TRH was not necessarily due to an improvement of cerebellar function, because TRH receptors are widely distributed throughout the central nervous system.

scholarly journals Foreign accent syndrome as a developmental motor speech disorder

Cortex ◽  
2009 ◽  
Vol 45 (7) ◽  
pp. 870-878 ◽  
Author(s):  
Peter Mariën ◽  
Jo Verhoeven ◽  
Peggy Wackenier ◽  
Sebastiaan Engelborghs ◽  
Peter P. De Deyn
Keyword(s):  
Speech Disorder ◽  
Foreign Accent ◽  
Motor Speech ◽  
Motor Speech Disorder ◽  
Foreign Accent Syndrome
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