Combined Local and Systemic Ozone Therapy in the Treatment of the Low Back Pain: A Proposed Protocol and a Suggested Mechanism of Action

2021 ◽  
pp. 1-6
Author(s):  
Emma Borrelli
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Mechanism Of Action ◽  
Low Back ◽  
Ozone Therapy

scholarly journals Effectiveness of ozone therapy compared to other therapies for low back pain: a systematic review with meta-analysis of randomized clinical trials

2019 ◽  
Vol 69 (5) ◽  
pp. 493-501 ◽  
Author(s):  
Raul Ribeiro de Andrade ◽  
Olavo Barbosa de Oliveira-Neto ◽  
Luciano Timbó Barbosa ◽  
Isabelle Oliveira Santos ◽  
Célio Fernando de Sousa-Rodrigues ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Low Back Pain ◽  
Back Pain ◽  
Randomized Clinical Trials ◽  
Meta Analysis ◽  
Low Back ◽  
Ozone Therapy

scholarly journals Efficacy of intradiscal ozone gas therapy combined with physical therapy in contained lumber disc prolapse

2016 ◽  
Vol 44 (3) ◽  
pp. 146-151
Author(s):  
Mohammad Moniruzzaman ◽  
Md Shahadat Hosssain ◽  
Md Ruhul Amin ◽  
Moshiur Rahman Khasru ◽  
Md Azizur Rahman ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Physical Therapy ◽  
Oswestry Disability Index ◽  
Positive Outcome ◽  
Outcome Variable ◽  
Low Back ◽  
Disc Prolapse ◽  
Ozone Therapy ◽  
College Hospital

Percutaneous intra-discal ozone therapy has promising results in contained lumber disc prolapse but the effectiveness of this treatment has been tested in large clinical studies show a positive outcome in 70%–80% of patients. To increase success rate of ozone discectomy and prevention of disc surgery, intradiscal ozone therapy combined with physical therapy may bring new options for the management of low back pain (LBP) due to lumber disc prolpase. This prospective experimental study was done from August 2014 to Octber 2014 at the Popular Medical College Hospital, Dhanmondi, Dhaka, Bangladesh with the intention to assess the efficacy of percutaneous intra-discal ozone therapy combined with physical therapy in acute and chronic low back pain due to contained prolapsed intervertebral lumber disc (PLID). Seven (7) ml of oxygen-ozone mixture at a concentration of 30 mc/ml was injected in the disc by ozone resistant syringe over a period of 15-20 seconds. All patients got physiotherapy for 30 minutes, two times/day, up to two weeks and strictly maintained activities of daily living (ADL). The main outcome variable was VAS(Visual Analogue Scale) & ODI (Oswestry Disability Index). 100% patient experienced radiation of pain in the leg before ozone gas & physical therapy and 90% had relieved radiation till 4th week. The reduction of VAS score from baseline to four weeks following treatment was 8.0±1.63 to 0.30±0.95. Reduction of Oswestry Disability Index (ODI) from baseline to four weeks following treatment was 37.7±6.5 to 15.8±1.0. Percutaneous intra-discal ozone therapy in combination with physical therapy is an effective treatment for management of low back pain (LBP) due to contained lumber disc prolpase.Bangladesh Med J. 2015 Sep; 44 (3): 146-151

Ozone injection therapy for intervertebral disc herniation

2020 ◽  
Vol 136 (1) ◽  
pp. 88-106
Author(s):  
Filippo Migliorini ◽  
Nicola Maffulli ◽  
Jörg Eschweiler ◽  
Marcel Bestch ◽  
Markus Tingart ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Disc Herniation ◽  
Lumbar Disc ◽  
Current Evidence ◽  
Intervertebral Disc Herniation ◽  
Low Back ◽  
Ozone Therapy ◽  
Ozone Injection

Abstract Introduction Lumbar disc herniation (LDH) is a common cause of low back pain (LBP). Recently, in the setting of LBP caused by LDH, a growing interest in ozone therapies has been observed. Source of data Recent published literatures. Areas of agreement Being low back pain more common in the elderlies, exploring conservative alternatives to the surgical intervention is of especial interest. Areas of controversy Efficacy and feasibility of ozone injections for LDH is debated. Several clinical studies showed controversial results, and the true benefit has not yet been clarified. Growing points Systematically summarize current evidences, analyze the quantitative available data and investigate the role of percutaneous ozone therapy for LDH. Areas timely for developing research Current evidence encourage the use of ozone therapy for LBP from LDH. These conclusions should be interpret in light of the limitations of the present study.

scholarly journals Comparison among different therapeutic techniques to treat low back pain: a monitored randomized study

Ozone Therapy ◽  
2016 ◽  
Vol 1 (1) ◽  
pp. 17
Author(s):  
Luca Morelli ◽  
Simona Carla Bramani ◽  
Marco Cantaluppi ◽  
Mara Pauletto ◽  
Alessandro Scuotto
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Randomized Study ◽  
Functional Limitation ◽  
Low Back ◽  
Ozone Therapy ◽  
Pain Disability ◽  
Treatment Data ◽  
Disability Questionnaire

Idiopathic low back pain can be considered as a chronic condition, characterized by recurrent episodes of pain and functional limitation. The aim of this study is to compare two therapeutic methods to treat this chronic disease: the oxygen-ozone therapy and the diathermy through Tear<sup>®</sup> therapy. Two groups of 10 patients each who suffered from postural idiopathic low back pain due to different pathologies have been recruited. All selected patients have been evaluated through spinometry and have been given the <em>Oswestry low back pain disability questionnaire</em> to fill in at the beginning of the treatments and at the end of them with a three-month follow-up. The first group underwent a diathermy treatment through Tecar<sup>®</sup> therapy, whilst the second group received an oxygen-ozone therapy treatment through a paravertebral lumbar infiltration; both treatments have been associated with a standard physiokinesitherapy treatment. Data collected through Formetric spinometry show an improvement in both groups, but in the second group (treated with oxygen-ozone therapy+physiokinesitherapy), the improvement is greater (from 6% to 57%) against the first group (from 20% to 38%). In conclusion, the study has cor roborated the validity of both treatments leading to improvement of symptomatology, but while one treatment leads to some relapses after a few months, the second one has a greater healing effect, which preserves over time.

scholarly journals Ozone Nucleolysis for Management of Pain and Disability in Prolapsed Lumber Intervertebral Disc

2009 ◽  
Vol 15 (3) ◽  
pp. 330-334 ◽  
Author(s):  
G. Das ◽  
S. Ray ◽  
S. Ishwarari ◽  
M. Roy ◽  
P. Ghosh
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Disc Herniation ◽  
Clinical Signs ◽  
Therapeutic Outcome ◽  
Oxygen Mixture ◽  
Low Back ◽  
Ozone Therapy ◽  
Lumber Disc Herniation ◽  
One Year

The prevalence rate of low back pain in a number of studies ranged from 22% to 65% in one year, and lifetime prevalence ranged from 11% to 84%. Over the years many percutaneous minimally invasive therapeutic modalities have evolved. Intradiscal oxygen-ozone therapy has also showed promising results. We undertook a prospective cohort study to evaluate the therapeutic outcome of oxygen-ozone therapy on patients with lumber disc herniation in the Indian population. After obtaining ethical committee and investigational review board permission, 53 consecutive patients complying with selection criteria were treated with a single session of oxygen-ozone therapy. All presented with clinical signs of lumber nerve root compression supported by CT and MRI findings. All patients received 3–7 ml of ozone-oxygen mixture at an ozone concentration of 29–32 mc/ml of oxygen. Therapeutic outcome was assessed after three weeks, three months, six months, one year and two years on a visual analog scale and Oswestry low back pain disability questionnaire. Pain intensity was significantly reduced following treatment (VAS baseline 7.58 ± 0.86, after three weeks 2.75 ± 1.42 and after two years 2.64 ± 2.14). Similarly the Oswestry disability index showed a remarkable improvement in the functional status of the patients (p<0.05). No major complication was observed in this case series. Oxygen-ozone treatment is highly effective in relieving low back pain due to lumber disc herniation.

scholarly journals Ozone Therapy as a Treatment for Low Back Pain Secondary to Herniated Disc: A Systematic Review and Meta-analysis of Randomized Controlled Trials

2012 ◽  
Vol 2;15 (2;3) ◽  
pp. E115-E129
Author(s):  
Erich T. Fonoff
Keyword(s):  
Systematic Review ◽  
Low Back Pain ◽  
Back Pain ◽  
Pain Relief ◽  
Randomized Trials ◽  
Meta Analysis ◽  
Low Back ◽  
Ozone Therapy ◽  
Randomized Controlled

Background: Low back pain (LBP) is one of the most common and important health problems affecting the population worldwide and remains mostly unsolved. Ozone therapy has emerged as an additional treatment method. Questions persist concerning its clinical efficacy. Objective: The purpose of our study was to evaluate the therapeutic results of percutaneous injection of ozone for low back pain secondary to disc herniation. Study Design: A systematic review and meta-analysis of randomized controlled trials. Methods: A comprehensive literature search was conducted using all electronic databases from 1966 through September 2011. The quality of individual articles was assessed based on the modified Cochrane review criteria for randomized trials and criteria from the Agency for Healthcare Research and Quality. Outcome Parameters: The outcome measure was short-term pain relief of at least 6 months or long-term pain relief of more than 6 months. Results: Eight observational studies were included in the systematic review and 4 randomized trials in the meta-analysis. The indicated level of evidence for long-term pain relief was II-3 for ozone therapy applied intradiscally and II-1 for ozone therapy applied paravertebrally. The grading of recommendation was 1C for intradiscal ozone therapy and 1B for paravertebral ozone therapy. Limitations: The main limitations of this review are the lack of precise diagnosis and the frequent use of mixed therapeutic agents. The meta-analysis included mainly active-control trials. No placebo-controlled trial was found. Conclusions: Ozone therapy appears to yield positive results and low morbidity rates when applied percutaneously for the treatment of chronic low back pain. Key words: Low back pain, oxygen-ozone, ozone therapy, chronic pain, failed back surgery syndrome.

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