Mechanism of Action of Oxygen Ozone Therapy in the Treatment of Disc Herniation and Low Back Pain

2010 ◽  
pp. 123-125 ◽  
Author(s):  
Emma Borrelli
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Disc Herniation ◽  
Mechanism Of Action ◽  
Low Back ◽  
Ozone Therapy

Ozone injection therapy for intervertebral disc herniation

2020 ◽  
Vol 136 (1) ◽  
pp. 88-106
Author(s):  
Filippo Migliorini ◽  
Nicola Maffulli ◽  
Jörg Eschweiler ◽  
Marcel Bestch ◽  
Markus Tingart ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Disc Herniation ◽  
Lumbar Disc ◽  
Current Evidence ◽  
Intervertebral Disc Herniation ◽  
Low Back ◽  
Ozone Therapy ◽  
Ozone Injection

Abstract Introduction Lumbar disc herniation (LDH) is a common cause of low back pain (LBP). Recently, in the setting of LBP caused by LDH, a growing interest in ozone therapies has been observed. Source of data Recent published literatures. Areas of agreement Being low back pain more common in the elderlies, exploring conservative alternatives to the surgical intervention is of especial interest. Areas of controversy Efficacy and feasibility of ozone injections for LDH is debated. Several clinical studies showed controversial results, and the true benefit has not yet been clarified. Growing points Systematically summarize current evidences, analyze the quantitative available data and investigate the role of percutaneous ozone therapy for LDH. Areas timely for developing research Current evidence encourage the use of ozone therapy for LBP from LDH. These conclusions should be interpret in light of the limitations of the present study.

scholarly journals Ozone Nucleolysis for Management of Pain and Disability in Prolapsed Lumber Intervertebral Disc

2009 ◽  
Vol 15 (3) ◽  
pp. 330-334 ◽  
Author(s):  
G. Das ◽  
S. Ray ◽  
S. Ishwarari ◽  
M. Roy ◽  
P. Ghosh
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Disc Herniation ◽  
Clinical Signs ◽  
Therapeutic Outcome ◽  
Oxygen Mixture ◽  
Low Back ◽  
Ozone Therapy ◽  
Lumber Disc Herniation ◽  
One Year

The prevalence rate of low back pain in a number of studies ranged from 22% to 65% in one year, and lifetime prevalence ranged from 11% to 84%. Over the years many percutaneous minimally invasive therapeutic modalities have evolved. Intradiscal oxygen-ozone therapy has also showed promising results. We undertook a prospective cohort study to evaluate the therapeutic outcome of oxygen-ozone therapy on patients with lumber disc herniation in the Indian population. After obtaining ethical committee and investigational review board permission, 53 consecutive patients complying with selection criteria were treated with a single session of oxygen-ozone therapy. All presented with clinical signs of lumber nerve root compression supported by CT and MRI findings. All patients received 3–7 ml of ozone-oxygen mixture at an ozone concentration of 29–32 mc/ml of oxygen. Therapeutic outcome was assessed after three weeks, three months, six months, one year and two years on a visual analog scale and Oswestry low back pain disability questionnaire. Pain intensity was significantly reduced following treatment (VAS baseline 7.58 ± 0.86, after three weeks 2.75 ± 1.42 and after two years 2.64 ± 2.14). Similarly the Oswestry disability index showed a remarkable improvement in the functional status of the patients (p<0.05). No major complication was observed in this case series. Oxygen-ozone treatment is highly effective in relieving low back pain due to lumber disc herniation.

scholarly journals Rasterstereographic Analysis of Lateral Shift in Patients with Lumbar Disc Herniation: A Case Control Study

2018 ◽  
Vol 2018 ◽  
pp. 1-8
Author(s):  
Britta K. Krautwurst ◽  
Jürgen R. Paletta ◽  
Sylvia Mendoza ◽  
Adrian Skwara ◽  
Melvin Mohokum
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Pain Intensity ◽  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Pelvic Tilt ◽  
Lumbar Disc ◽  
Lateral Shift ◽  
Healthy Controls ◽  
Low Back

Objective. Detection of a lateral shift (LS) in patients with diagnosed disc herniation compared to healthy controls. Summary of Background Data. A specific lateral shift (LS) pattern is observed in patients with disc herniation and low back pain, as shown in earlier studies. Methods. Rasterstereography (RS) was used to investigate the LS. Thirty-nine patients with lumbar disc herniation diagnosed by radiological assessment and low back pain and/or leg pain (mean age 48.2 years, mean BMI 28.5, 28 males and 11 females) and 36 healthy controls (mean age 47.4 years, mean BMI 25.7, 25 males and 11 females) were analysed. LS, pelvic tilt, pelvic inclination, lordotic angle, and trunk torsion were assessed. Results. The patient group showed a nonsignificant increase in LS, that is, 5.6 mm compared to the healthy controls with 5.0 mm (p = 0.693). However, significant differences were found between groups regarding pelvic tilt in degrees (patients 5.9°, healthy controls 2.0°; p = 0.016), trunk torsion (patients 7.5°, controls 4.5°; p = 0.017), and lordotic angle (patients 27.5°, healthy controls 32.7°; p = 0.022). The correlation between pain intensity and the FFbH-R amounted 0.804 (p = < 0.01), and that between pain intensity and the pain disability index was 0.785 (p < 0.01). Discussion. Although some studies have illustrated LS with disc herniation and low back pain, the present findings demonstrate no significant increase in LS in the patient group compared to healthy controls. Conclusion. The patients with lumbar disc herniation did not demonstrate an increased LS compared to healthy controls. Other parameters like pelvic tilt and inclination seemed to be more suitable to identify changes in posture measured by RS in patients with low back pain or disc herniation.

scholarly journals HUBUNGAN ANTARA KADAR LIPID DARAH DENGAN DERAJAT HERNIASI DISKUS INTERVERTEBRALIS

2019 ◽  
Vol 36 (2) ◽  
Author(s):  
Elsa Ana Purika ◽  
Susi Aulina ◽  
Audry Devisanty Wuysang ◽  
Andi Alfian Zainuddin
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Total Cholesterol ◽  
Disc Herniation ◽  
Serum Lipid ◽  
Low Back ◽  
Spearman Correlation ◽  
Lipid Levels ◽  
Serum Lipid Levels ◽  
Vertebral Disc

   THE CORRELATION BETWEEN SERUM LIPID LEVELS WITH THE SEVERITY OF INTER-VERTEBRAL DISC HERNIATIONABSTRACTIntroduction: Inter-vertebral Disc Herniation (IDH) is one of the common causes of low back pain (LBP). High level of blood lipids is a risk factor for atherosclerosis, and responsible as the cause of decreased blood supply to the intervertebral discs which basically has minimal vascularization, thus, it is estimated that there is a relationship between blood lipid levels and IDH.Aim: To identify the correlation between serum lipid levels with the severity of IDH.Methods: Clinical trials with cross sectional designs were carried out on subjects with IDH during April to June 2018 in Dr. Wahidin Sudirohusodo Hospital, Makassar. Serum lipid levels (HDL, LDL, triglyceride and total cholesterol) were examined and the degree of disc herniation (1 to 4) was assessed. Data analyzed using the Spearman correlation test.Results: In this study there were 40 subjects, 15 males and 25 females, with mean age 50.75 (30-62) years old. Most patients were found with degrees of IDH 2 and 3 (total 75%). The Spearman correlation test showed that there was a negative correlation between HDL with degrees of IDH, as well as a positive correlation between LDL and triglycerides with degrees of IDH, but there was no correlation between total cholesterol levels with degrees of IDH.Discussion: The lower the HDL level, the higher the degree of IDH. On the other hand, the higher the level of LDL and triglycerides, the higher the degree of IDH.Keywords: Inter-vertebral disc herniation, low back pain, serum lipid levelsABSTRAKPendahuluan: Herniasi diskus intervertebralis (HDI) merupakan salah satu penyebab nyeri punggung bawah (LBP) yang cukup sering terjadi. Tingginya kadar lipid darah merupakan faktor risiko untuk aterosklerosis, dan bertanggung jawab sebagai penyebab menurunnya suplai darah pada diskus intervertebralis yang pada dasarnya sudah minim vaskularisasi, sehingga diperkirakan terdapat hubungan antara kadar lipid darah dengan penyakit degenerasi diskus intervertebralis.Tujuan: Mengetahui hubungan antara kadar lipid darah dengan derajat herniasi diskus intervertebralis.Metode: Penelitian potong lintang terhadap subjek dengan herniasi diskus intervertebralis yang berobat ke RSUP Dr. Wahidin Sudirohusodo, Makassar, selama bulan April-Juni 2018. Dilakukan penilaian kadar lipid darah (HDL, LDL, trigiliserida, dan kolesterol total) serta derajat herniasi diskus intervertebralis (1 sampai 4) berdasarkan gejala klinis dan gambaran MRI. Analisis data menggunakan uji korelasi Spearman.Hasil: Didapatkan 40 subjek yang terdiri atas 15 orang laki-laki dan 25 orang perempuan dengan rerata usia 50,75 (30–62) tahun. Mayoritas subjek mengalami HDI derajat 2 dan 3 (total 75%). Uji korelasi Spearman menunjukkan adanya korelasi negatif antara kadar HDL dengan derajat HDI, serta korelasi positif antara kadar LDL dan trigliserida dengan derajat HDI, namun tidak terdapat korelasi antara kadar kolesterol total dengan derajat HDI.Diskusi: Semakin rendah kadar HDL, maka semakin berat derajat HDI. Sebaliknya semakin tinggi kadar LDL dan trigliserida, maka semakin berat derajat HDI.Kata kunci: Herniasi diskus intervertebralis, kadar lipid darah, nyeri punggung bawah

scholarly journals Gait adaptations in low back pain patients with lumbar disc herniation: trunk coordination and arm swing

2010 ◽  
Vol 20 (3) ◽  
pp. 491-499 ◽  
Author(s):  
Yun Peng Huang ◽  
Sjoerd M. Bruijn ◽  
Jian Hua Lin ◽  
Onno G. Meijer ◽  
Wen Hua Wu ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Lumbar Disc ◽  
Low Back ◽  
Arm Swing ◽  
Pain Patients

scholarly journals Effectiveness of ozone therapy compared to other therapies for low back pain: a systematic review with meta-analysis of randomized clinical trials

2019 ◽  
Vol 69 (5) ◽  
pp. 493-501 ◽  
Author(s):  
Raul Ribeiro de Andrade ◽  
Olavo Barbosa de Oliveira-Neto ◽  
Luciano Timbó Barbosa ◽  
Isabelle Oliveira Santos ◽  
Célio Fernando de Sousa-Rodrigues ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Low Back Pain ◽  
Back Pain ◽  
Randomized Clinical Trials ◽  
Meta Analysis ◽  
Low Back ◽  
Ozone Therapy

scholarly journals Efficacy of intradiscal ozone gas therapy combined with physical therapy in contained lumber disc prolapse

2016 ◽  
Vol 44 (3) ◽  
pp. 146-151
Author(s):  
Mohammad Moniruzzaman ◽  
Md Shahadat Hosssain ◽  
Md Ruhul Amin ◽  
Moshiur Rahman Khasru ◽  
Md Azizur Rahman ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Physical Therapy ◽  
Oswestry Disability Index ◽  
Positive Outcome ◽  
Outcome Variable ◽  
Low Back ◽  
Disc Prolapse ◽  
Ozone Therapy ◽  
College Hospital

Percutaneous intra-discal ozone therapy has promising results in contained lumber disc prolapse but the effectiveness of this treatment has been tested in large clinical studies show a positive outcome in 70%–80% of patients. To increase success rate of ozone discectomy and prevention of disc surgery, intradiscal ozone therapy combined with physical therapy may bring new options for the management of low back pain (LBP) due to lumber disc prolpase. This prospective experimental study was done from August 2014 to Octber 2014 at the Popular Medical College Hospital, Dhanmondi, Dhaka, Bangladesh with the intention to assess the efficacy of percutaneous intra-discal ozone therapy combined with physical therapy in acute and chronic low back pain due to contained prolapsed intervertebral lumber disc (PLID). Seven (7) ml of oxygen-ozone mixture at a concentration of 30 mc/ml was injected in the disc by ozone resistant syringe over a period of 15-20 seconds. All patients got physiotherapy for 30 minutes, two times/day, up to two weeks and strictly maintained activities of daily living (ADL). The main outcome variable was VAS(Visual Analogue Scale) & ODI (Oswestry Disability Index). 100% patient experienced radiation of pain in the leg before ozone gas & physical therapy and 90% had relieved radiation till 4th week. The reduction of VAS score from baseline to four weeks following treatment was 8.0±1.63 to 0.30±0.95. Reduction of Oswestry Disability Index (ODI) from baseline to four weeks following treatment was 37.7±6.5 to 15.8±1.0. Percutaneous intra-discal ozone therapy in combination with physical therapy is an effective treatment for management of low back pain (LBP) due to contained lumber disc prolpase.Bangladesh Med J. 2015 Sep; 44 (3): 146-151

scholarly journals Comparison among different therapeutic techniques to treat low back pain: a monitored randomized study

Ozone Therapy ◽  
2016 ◽  
Vol 1 (1) ◽  
pp. 17
Author(s):  
Luca Morelli ◽  
Simona Carla Bramani ◽  
Marco Cantaluppi ◽  
Mara Pauletto ◽  
Alessandro Scuotto
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Randomized Study ◽  
Functional Limitation ◽  
Low Back ◽  
Ozone Therapy ◽  
Pain Disability ◽  
Treatment Data ◽  
Disability Questionnaire

Idiopathic low back pain can be considered as a chronic condition, characterized by recurrent episodes of pain and functional limitation. The aim of this study is to compare two therapeutic methods to treat this chronic disease: the oxygen-ozone therapy and the diathermy through Tear<sup>®</sup> therapy. Two groups of 10 patients each who suffered from postural idiopathic low back pain due to different pathologies have been recruited. All selected patients have been evaluated through spinometry and have been given the <em>Oswestry low back pain disability questionnaire</em> to fill in at the beginning of the treatments and at the end of them with a three-month follow-up. The first group underwent a diathermy treatment through Tecar<sup>®</sup> therapy, whilst the second group received an oxygen-ozone therapy treatment through a paravertebral lumbar infiltration; both treatments have been associated with a standard physiokinesitherapy treatment. Data collected through Formetric spinometry show an improvement in both groups, but in the second group (treated with oxygen-ozone therapy+physiokinesitherapy), the improvement is greater (from 6% to 57%) against the first group (from 20% to 38%). In conclusion, the study has cor roborated the validity of both treatments leading to improvement of symptomatology, but while one treatment leads to some relapses after a few months, the second one has a greater healing effect, which preserves over time.

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