scholarly journals Herbal Medicines use in Pregnancy in Northern Cyprus

2021 ◽  
pp. 487-504
Author(s):  
Eda Tülek ◽  
Filiz Yarici ◽  
Dudu Özkum Yavuz ◽  
Mustapha Bulama Modu ◽  
Filiz Meriçli
Keyword(s):  
Medicinal Plants ◽  
Pregnant Women ◽  
Herbal Medicines ◽  
Community Pharmacists ◽  
Medicinal Products ◽  
Herbal Medicinal Products ◽  
Northern Cyprus ◽  
Medicines Use ◽  
Herbal Medicinal ◽  
In Pregnancy

Objective: To identify the herbal medicinal products used in pregnancy in community pharmacies, the approach of pharmacists in Northern Cyprus and to compare the availability of the most commonly mentioned medicinal plants in accessible databases, in Northern Cyprus. Design: Questionnaire was designed and administered to 263 community pharmacists in Northern Cyprus and gathered the data on herbal medicinal products they had and recommended to pregnant women. Databases such as ScienceDirect, PubMed, OpenAcces Journals were searched through the Near East University Grand Library’s Online Resources for keywords relating to the ‘herbal medicine’, ‘pregnancy’ ‘pregnant women’, ‘herbal products’. Descriptive statistics was used with IBM® Statistical product and service solutions software platform. Location/Setting: Northern Cyprus Outcome Measures: Herbal medicinal products used and recommended in pregnancy by community pharmacists in Northern Cyprus were identified. It has also been determined which of the most used plants in the world are grown in Northern Cyprus. Results: The most recommended herbal pharmaceutical forms were herbal lozenges (n = 76, 31%), then herbal form of teas (n = 60, 24%), herbal oils (n = 57, 23%), herbal capsules (n = 36, 14%), other pharmaceutical forms (n=20, 8%). Within the limitation of our literature search, totally 650 medicinal plants (single or formula) used in pregnancy were determined.  Out of these 74 were mostly used worldwide, and it was discovered that 56 species out of these plants are grown or cultivated; 18 of the compiled species were imported species some of the genera have species growing naturally growing in Cyprus. Conclusion: Pregnant women in Cyprus also follow their counterparts in other countries in developing interest in herbal medicines. The number of herbal medicines in the pharmacies owned by Turkish Cypriots is small. Interestingly, the result of this study showed that the pharmacists that were mainly Turkish Cypriots were found not to be selling herbal medicinal products to pregnant women without doctor’s prescriptions. This study recommends that the herbal medicines use in pregnancy should be the ones that have undergone in-depth evidence-based scientific researches with clinically proven efficacy that are known not only to the healthcare professionals such as medical doctors, midwives but also the pharmacists and the general public.

Unraveling the Complexities of Brazilian Regulations for Medicinal Plants and Herbal Medicinal Products

2019 ◽  
pp. 1-12
Author(s):  
Ana Cecília Bezerra Carvalho ◽  
Melina Cossote Kumoto ◽  
João Paulo Silvério Perfeito
Keyword(s):  
Medicinal Plants ◽  
Medicinal Products ◽  
Herbal Medicinal Products ◽  
Herbal Medicinal

scholarly journals Pharmaco-epidemiological research on herbal medicinal products in the paediatric population: data from the PhytoVIS study

2019 ◽  
Vol 179 (3) ◽  
pp. 507-512
Author(s):  
Karen Nieber ◽  
Esther Raskopf ◽  
Johanna Möller ◽  
Olaf Kelber ◽  
Robert Fürst ◽  
...  
Keyword(s):  
Adverse Events ◽  
Common Cold ◽  
Sleep Disturbances ◽  
Skin Diseases ◽  
Herbal Medicines ◽  
Paediatric Population ◽  
Clinical Effects ◽  
Medicinal Products ◽  
Herbal Medicinal Products ◽  
Herbal Medicinal

AbstractIn paediatrics, clinical study data are limited, especially on herbal medicinal products. To address this gap, 2063 datasets from the paediatric population were evaluated in the PhytoVIS data base. By screening for paediatric data, information on indication, gender, treatment, co-medication and tolerability were evaluated. The majority of patients was treated because of common cold, fever, digestive complaints, skin diseases, sleep disturbances and anxiety. The perceived effect of the therapy was rated in 84% of the patients as very good or good without adverse events. The data shed light on a still neglected field of phyto-pharmacotherapy by giving information on the use of herbal medicines in an unselected cohort of paediatric patients. The results confirm the good clinical effects and safety of herbal medicinal products in this patient population and show that they are widely used in Germany.What is Known:• In Germany, about 85% of children receive one or more herbal medicinal products per year.• Despite international initiatives to promote clinical research in paediatrics, there are still many gaps of knowledge in the use of drugs in paediatrics.What is New:• The PhytoVIS project evaluated 2063 data sets from the paediatric population using herbal medicinal products.• The majority of patients was treated because of common cold, fever, digestive complaints, skin diseases, sleep disturbances and anxiety, and 84% of the patients rated the therapy as very good or good without adverse events.

Herbalism and the menopause

2002 ◽  
Vol 8 (2) ◽  
pp. 72-74 ◽  
Author(s):  
Edzard Ernst
Keyword(s):  
Herbal Medicines ◽  
Trial Data ◽  
Black Cohosh ◽  
Effective Alternative ◽  
Medicinal Products ◽  
Herbal Medicinal Products ◽  
Herbal Medicinal

Herbal medicinal products are often sold as a safe and effective alternative to HRT. Sizeable sets of trial data exist for black cohosh and soy. For other herbal medicines, only isolated trials have emerged, and their number is too low to enable one to arrive at valid conclusions. Collectively the data for black cohosh do not prove efficacy. The evidence for soy is encouraging but not compelling. Neither black cohosh nor soy is associated with major safety problems. Further research is warranted to closer define the role of herbal medicines for the menopause.

scholarly journals The potential of herbal extracts to inhibit SARS-CoV-2: a pilot study

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Michela Luisa De Pellegrin ◽  
Anette Rohrhofer ◽  
Philipp Schuster ◽  
Barbara Schmidt ◽  
Philipp Peterburs ◽  
...  
Keyword(s):  
Respiratory Infections ◽  
Quantitative Polymerase Chain Reaction ◽  
Herbal Medicines ◽  
Vero Cells ◽  
Cell Culture Supernatant ◽  
Herbal Extracts ◽  
Medicinal Products ◽  
Herbal Medicinal Products ◽  
Herbal Medicinal

Abstract Background Herbal medicinal products have a long-standing history of use in the therapy of common respiratory infections. We sought to assess the potential of five validated herbal extracts regarding their ability to restrict SARS-CoV-2 replication in vitro: Bronchipret thyme-ivy (BRO TI), Bronchipret thyme-primrose (BRO TP), Imupret (IMU), Sinupret extract (SINx) and Tonsipret (TOP). Methods Vero cells were incubated with different concentrations of herbal extracts and infected with SARS-CoV-2 for 48 hours. The inhibition of viral replication was assessed by determination of the viral RNA load in the cell culture supernatant using quantitative polymerase chain reaction (qPCR). Results SARS-CoV-2 RNA load was reduced by non-cytotoxic concentrations of BRO-TP (up to approximately 1,000-fold) and, to a lesser extent, IMU and TOP (approximately 10-fold). Conclusions Some herbal extracts showed a promising in vitro effectiveness against SARS-CoV-2, suggesting an antiviral potential of herbal medicinal products. The potential of herbal medicines to restrict SARS-CoV-2 and to treat COVID-19 should be investigated further in a clinical setting.

scholarly journals Determination of Anthracene Derivatives in Herbal Medicines

2021 ◽  
Vol 11 (2) ◽  
pp. 104-114
Author(s):  
O. V. Evdokimova ◽  
A. V. Beketova ◽  
M. N. Lyakina
Keyword(s):  
Comparative Analysis ◽  
Herbal Medicines ◽  
Quality Standards ◽  
Test Methods ◽  
Medicinal Products ◽  
Herbal Medicinal Products ◽  
Herbal Preparations ◽  
Anthracene Derivatives ◽  
Herbal Medicinal

The relevance of this study stems from the need for alignment of test methods used for identification and assay of anthracene derivatives in herbal preparations and herbal medicinal products. The aim of the study was to analyse Russian and international quality standards and to identify the most specific and sensitive test methods that could be used for herbal medicines containing anthracene derivatives. The comparative analysis of requirements in the Identification, Determination of major classes of bioactive compounds, and Assay parts of the Russian and foreign pharmacopoeial monographs for herbal preparations and herbal medicinal products containing anthracene derivatives, demonstrated that the main test method used for identification is thin layer chromatography, while assays most often rely on spectrophotometry. The so-called “consistent standardisation” principle is implemented in the Russian quality standards as regards alignment of methods used for anthracene derivative determination in herbal preparations (i.e. active pharmaceutical ingredients, APIs) and herbal medicinal products containing these APIs. The comparative analysis of requirements in the Russian and foreign quality standards for herbal medicines containing anthracene derivatives demonstrated the need for elaboration of two general chapters: Qualitative analysis of anthracene derivatives in herbal medicines and Quantitative analysis of anthracene derivatives in herbal medicines.

scholarly journals Dissolution test of herbal medicines containing Paullinia cupana: validation of methods for quantification and assessment of dissolution

2011 ◽  
Vol 47 (2) ◽  
pp. 269-277 ◽  
Author(s):  
Sandra Alves de Sousa ◽  
Henrique Pascoa ◽  
Edemilson Cardoso da Conceição ◽  
Suzana Ferreira Alves ◽  
Danielle Guimarães Almeida Diniz ◽  
...  
Keyword(s):  
Condensed Tannins ◽  
Herbal Medicines ◽  
Dosage Forms ◽  
Dissolution Behavior ◽  
Therapeutic Action ◽  
Medicinal Products ◽  
Herbal Medicinal Products ◽  
Dissolution Studies ◽  
Paullinia Cupana ◽  
Herbal Medicinal

"Guaraná" (Paullinia cupana) is used as a physical activity enhancer and stimulator due to its methylxanthines and condensed tannins. The aim of this work was to evaluate the dissolution behavior of five herbal medicines in the form of capsules and tablets containing guaraná. Assay and dissolution methods were validated and results obtained allowed simultaneous marker quantification with precision, accuracy, selectivity and robustness. Findings showed that 100% of the herbal medicinal products analyzed did not provide satisfactory results concerning the presence of four markers, 60% had three markers (caffeine, catechin and epicatechin), while 40% had only caffeine at tested dosage forms. In addition, after 30 minutes, only capsule A showed at least 80% of the dissolved markers. In other capsules, marker dissolution did not exceed 60% whereas 60% of the samples had some characteristic pharmacotechnical problems. These results evidence the need for rigorous quality control to help ensure the therapeutic action of these drugs. To this end, dissolution studies are an essential tool for quality assurance of herbal medicines.

scholarly journals Regulatory compliance of herbal medicines – A review

2019 ◽  
Vol 10 (4) ◽  
pp. 3127-3135
Author(s):  
Malathi Seshasayee Konda Ramadoss ◽  
Kailasam Koumaravelou
Keyword(s):  
Medicinal Product ◽  
Herbal Medicines ◽  
Regulatory Compliance ◽  
Global Market ◽  
World Health ◽  
Manufacturing Companies ◽  
Medicinal Products ◽  
Herbal Medicinal Product ◽  
Herbal Medicinal Products ◽  
Herbal Medicinal

Recently, herbal medicinal products (HMP) have gained importance and are extensively used in the prevention and treatment of various ailments. A commercial herbal medicinal product should comply with the regulatory requirements of quality, safety and efficacy. Currently, the standards and regulations of herbal medicinal products are varying from country to country, which poses a challenge to the manufacturing companies to place a standardized herbal product in the global market. Hence a collaborative effort must be taken both by regulatory bodies and the World Health Organization (WHO) to establish harmonized regulations for a herbal medicinal product. An attempt has been made in this review which may pave the way to meet out the constraints and challenges in the manufacturing and marketing of herbal medicinal product worldwide.

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