Estimating the population health burden of Lyme disease in Ontario, Canada: a microsimulation modelling approach

Demographic shifts towards an aging population are becoming a significant fiscal challenge for governments. Previous research has explored the fiscal consequences of the expanding elderly population, but the impact on the elderly’s health quality is less mentioned. The balanced relationship between elderly population health and public finance is a major concern of the global political agenda on the aging society. This article used cross-country panel data from 2000 to 2019 to examine the fiscal effect of the elderly health burden and the mediating role of healthcare resources. The results are demonstrated: The elderly health burden has a negative impact on fiscal balance, especially in aged society and longevity countries. Moreover, the mediating effect of healthcare resources is significant, whereby various forms of healthcare resources such as funds, labor, and facilities all have significant effects. Thus, the conceptual framework of elderly population health, healthcare resources, and public finance is confirmed that the elderly health burden specifically leads to the growing consumption of healthcare resources, which reduces the fiscal balance. It is concluded that reducing the elderly health burden and improving healthcare resource efficiencies are two feasible strategies to enhance fiscal sustainability.

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A system dynamics modelling approach to assess the impact of launching a new nicotine product on population health outcomes

Regulatory Toxicology and Pharmacology ◽

10.1016/j.yrtph.2017.03.012 ◽

2017 ◽

Vol 86 ◽

pp. 265-278 ◽

Cited By ~ 22

Author(s):

Andrew Hill ◽

Oscar M. Camacho

Keyword(s):

System Dynamics ◽

Health Outcomes ◽

Population Health ◽

System Dynamics Modelling ◽

Dynamics Modelling ◽

The Impact ◽

Modelling Approach

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Are long telomeres better than short? Relative contributions of genetically predicted telomere length to neoplastic and non-neoplastic disease risk and population health burden

PLoS ONE ◽

10.1371/journal.pone.0240185 ◽

2020 ◽

Vol 15 (10) ◽

pp. e0240185

Author(s):

Ekaterina Protsenko ◽

David Rehkopf ◽

Aric A. Prather ◽

Elissa Epel ◽

Jue Lin

Keyword(s):

Telomere Length ◽

Population Health ◽

Disease Risk ◽

Neoplastic Disease ◽

Health Burden ◽

Better Than

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New ultrastructural findings about Borrelia burgdorferi by cryofixation, negative staining, thin sectioning and scanning techniques

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100160467 ◽

1990 ◽

Vol 48 (3) ◽

pp. 582-583

Author(s):

S. F. Hayes ◽

M. D. Corwin ◽

T. G. Schwan ◽

D. W. Dorward ◽

W. Burgdorfer

Keyword(s):

Lyme Disease ◽

Borrelia Burgdorferi ◽

Structural Characterization ◽

Negative Staining ◽

Low Speed ◽

Thin Sectioning ◽

Ultrastructural Findings

Characterization of Borrelia burgdorferi strains by means of negative staining EM has become an integral part of many studies related to the biology of the Lyme disease organism. However, relying solely upon negative staining to compare new isolates with prototype B31 or other borreliae is often unsatisfactory. To obtain more satisfactory results, we have relied upon a correlative approach encompassing a variety EM techniques, i.e., scanning for topographical features and cryotomy, negative staining and thin sectioning to provide a more complete structural characterization of B. burgdorferi.For characterization, isolates of B. burgdorferi were cultured in BSK II media from which they were removed by low speed centrifugation. The sedimented borrelia were carefully resuspended in stabilizing buffer so as to preserve their features for scanning and negative staining. Alternatively, others were prepared for conventional thin sectioning and for cryotomy using modified procedures. For thin sectioning, the fixative described by Ito, et al.

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