postmortem ct
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Author(s):  
Jannah Pye ◽  
Mathieu Spriet ◽  
Penny Dow ◽  
Scott Katzman ◽  
Brian G. Murphy

Abstract OBJECTIVE To describe clinical, imaging, gross, and histopathological abnormalities associated with osteochondral necrosis of the femoral condyles in foals and identify features suggestive of a common pathogenesis. ANIMALS 8 Thoroughbred foals euthanized with a presumptive diagnosis of necrosis of the femoral condyles. PROCEDURES Postmortem CT was performed on all distal femoral epiphyseal samples. The articular epiphyseal cartilage complex (AECC) of affected distal femurs was examined grossly and histologically, focusing on lesions of interest identified on CT images. RESULTS 7 foals were between 9 and 23 days old at the time of euthanasia; 1 foal was 85 days old. Concurrent illness (neonatal maladjustment syndrome, neonatal isoerythrolysis, or infection such as enteritis and omphalitis) was diagnosed in 7 foals. The characteristic antemortem radiographic and postmortem CT finding was a crescent-shaped osteochondral flap displaced from the affected medial femoral condyle. Synovial fluid cytology from affected joints was either within normal limits or consistent with mild inflammation. Histologically, all lesions were characterized by osteochondral necrosis and detachment of the AECC. In 6 foals, polymorphonuclear cells were found within growth cartilage canals, representing septic cartilage canals. CLINICAL RELEVANCE Osteochondral necrosis was interpreted to be secondary to bacterial colonization of the distal femoral AECC, evidenced by septic cartilage canals identified in 6 of 8 foals. This uncommon condition was previously thought to arise from an ischemic event, but the disease process was not well understood. An improved understanding of the pathogenesis of osteochondral necrosis is the first step in formulating more successful preventative and treatment strategies.


Author(s):  
Jakob Heimer ◽  
Vasiliki Chatzaraki ◽  
Wolf Schweitzer ◽  
Michael J. Thali ◽  
Thomas D. Ruder

Author(s):  
Jakob Heimer ◽  
Vasiliki Chatzaraki ◽  
Wolf Schweitzer ◽  
Michael J. Thali ◽  
Thomas D. Ruder

Abstract Background Cases of external hemorrhage are difficult to recognize on postmortem computed tomography (PMCT). Purpose To investigate the effects of blood loss on CT attenuation of the spleen, liver, kidneys, and lungs on PMCT and to assess the relationship between blood loss and organ weight. Methods A total of 125 cases with blood loss were sex- and age-matched to 125 control cases without blood loss. Individual organ attenuation was measured on transverse CT images. Organ weights of the liver, spleen, kidneys, and lung were extracted from the autopsy protocols. Results Organ weight was significantly lower in cases with blood loss (lung 30%, spleen 28%, kidneys 14%, liver 18%) than in controls. CT attenuation of the lungs was significantly lower (30%) in cases with blood loss than in controls. CT attenuation of the spleen and kidneys did not significantly differ between cases and controls. CT attenuation of the liver was significantly higher (25%) in cases with blood loss than in controls. Conclusion Blood loss decreases organ weight and CT attenuation of the lungs but appears to have no significant effect on CT attenuation of the spleen and kidneys. The increased liver attenuation in cases with blood loss compared to controls was an unexpected finding and remains challenging to explain. One probable interpretation refers to different levels of hepatic glycogen; however, further work is warranted to substantiate this hypothesis.


2021 ◽  
Vol 2 (2S) ◽  
pp. 42-43
Author(s):  
U. N. Tumanova ◽  
O. V. Savva ◽  
A. I. Shchegolev
Keyword(s):  

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Author(s):  
Fabio De-Giorgio ◽  
Gabriele Ciasca ◽  
Gennaro Fecondo ◽  
Alberto Mazzini ◽  
Marco De Spirito ◽  
...  

Abstract Using postmortem CT (PMCT), changes in the volume of the lateral cerebral ventricles (LCVs) and modifications of the radiodensity of cerebrospinal fluid (CSF) have been examined to identify a possible relationship between these changes and the time of death. Subsequent periodical CT scans termed “sequential scans” for ten corpses at known time of death were obtained, and a 3D segmentation of the entire LCV was carried out to measure its volume and radiodensity over time from ~ 5.5- h up to 273-h postmortem. A linear decrease of the LCV volume for all the cases was observed in the investigated time range, together with an overall logarithmic increase of radiodensity. Although a larger sampling should be performed to improve the result reliability, our finding suggests that the postmortem variation of CSF radiodensity can be a potentially useful tool in determining postmortem interval, a finding that is worthy of further investigation.


Author(s):  
Maiko Yoshida ◽  
Yohsuke Makino ◽  
Yumi Hoshioka ◽  
Naoki Saito ◽  
Rutsuko Yamaguchi ◽  
...  
Keyword(s):  

2021 ◽  
Vol 26 ◽  
pp. 200476
Author(s):  
Samuel Weber ◽  
Vera Barrera ◽  
Akos Dobay ◽  
Sabine Franckenberg ◽  
Michael Thali ◽  
...  
Keyword(s):  
Ct Scans ◽  

2021 ◽  
pp. 200459
Author(s):  
Moyu Yamamori ◽  
Tomoya Kobayashi ◽  
Seiji Shiotani ◽  
Kazunori Kaga ◽  
Hajime Saitou ◽  
...  

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