Chapter 8 looks at specific ways in which art can sometimes be crazy-making, with a detailed examination of three artist suicides. Research on artists and suicide, specifically, is sparse. We know as little about any artist’s reasons as we do about anyone else’s, but a few studies are have been done. And at least actuarially, in relation to level of overall risk, the good studies provide some helpful grounding. To get at a range of possible dynamics, none universal, in this chapter the author inspects the particular cases of Diane Arbus, Kurt Cobain, and Sylvia Plath. Specifically, the author examines how suicide sometimes comes at the end of a process of artistic redefinition. The artist tries something new, in terms of form or content, apparatus or theme, and the product, so unlike anything he or she has attempted before, seems at first outrageously right and satisfying. Sometimes that feeling lasts, sometimes it doesn’t. But either way, the new development occasions a risky and not necessarily valid reassessment of all prior artistic activity.