Most unifications of the classical or generalized Bernoulli, Euler, and Genocchi polynomials involve unifying any two or all of the three special types of polynomials (see, [1, 4, 9, 18, 19,21, 24–26, 30, 31]). In this paper, we introduce a new class of multiparameter Fubini-type gener-alized polynomials that unifies four families of higher order generalized Apostol-type polynomials such as the Apostol-Bernoulli, Apostol-Euler, Apostol-Genocchi, and Apostol-Fubini polynomials. Moreover, we obtain an explicit formula of these unified generalized polynomials in terms of the Gaussian hypergeometric function, and establish several symmetry identities.