Reperfused vs. Non-reperfused Myocardial Infarction: When to Use Which Model

There is a lack of understanding in the cardiac remodeling field regarding the use of non-reperfused MI and reperfused MI in animal models of myocardial infarction (MI). This Perspectives summarizes the consensus of the authors regarding how to select the optimum model for your experiments and is a part of ongoing efforts to establish rigor and reproducibility in cardiac physiology research.