Search of markers of alcoholization among ghrelin derivatives

The quantitative determination of unacylated ghrelin in rat sera in the course of prolonged (chronic) alcoholization during 6 months followed by alcohol withdrawal (in 1 and 7 days) was made by means of the rat unacylated ghrelin enzyme immunoassay kit (SPIBIO, France). Unacylated ghrelin was revealed in all samples both in control and experimental groups. The row data were treated by means of parametric and nonparametric statistic tests. The level of unacylated ghrelin was shown to double reduce in the course of prolonged alcoholization in rats. Ethanol withdrawal recovered the polypeptide content gradually with maximal indexes in 7 days after alcohol abolition but lower than in control rats. The possibilities of the use of unacylated ghrelin as a biochemical marker of alcoholization and its consequences are discussed.

Prospek Statistik Nonparametrik Metode Brown-Mood dalam Pendidikan Tinggi: Suatu Aplikasi dalam Regresi Linier Sederhana

: This paper has been used to give insight for the researches or the students of high school about nonparametric statistic and it’s applications at the analysis of simple regression specially to fit the regression line and the test of hypotheses. A regression line of estimation Y = a + bX, in nonparametric statistic a and b can be found way of manual with least square method. But in nonparametric statistic can be found way of manual with Brown-Mood method. The test of hypotheses for a and b from population with model of regression equalization Y = a + bX is used Brown-Mood method too. The statistic of test from Brown-Mood method as follow : x2 = with n, n1, and n2 follow steps from Brown-Mood.