The possibility of application of the International classification of functioning, restrictions of activity and health (ICF) at assessment of efficiency of rehabilitation actions of patients with brest cancer is presented in article. Experience of application of MKF at a stage of hospitalization of patients in a hospital and also in the remote period at 13 patients with breast cancer receiving antineoplastic treatment (chemotherapy, surgery, radiation therapy) is shown. Possibilities of use of MKF are good addition to the proved and standard scales and tests on diagnostics of extent of violations of various structures and functions of an organism. Further researches for development of specialized questionnaires on the basis of ICF taking into account specifics of diseases are required.