Drosophila acquires seconds-scale rhythmic behavior

Detection of the temporal structure of stimuli is crucial for prediction. While perception of interval timing is relevant for immediate behavioral adaptations, it has been scarcely investigated, especially in invertebrates. Here we examined if the fruit fly, Drosophila melanogaster, can acquire rhythmic behavior in the range of seconds. To this end, we developed a novel temporal conditioning paradigm utilizing repeated electric shocks. Combined automatic behavioral annotation and time-frequency analysis revealed that behavioral rhythms continued after cessation of the shocks. Furthermore, we found that aging impaired interval timing. This study thus not only demonstrated the ability of insects to acquire behavioral rhythms of a few seconds, but highlighted a life-course decline of temporal coordination, that is common also in mammals.

Information in Time Structure in the View of Carl Friedrich Von Weizsäcker

Information in the structure of time according to Carl Friedrich von Weizsäcker. These analyzes relate to the temporal conditioning of information in the context of the information society. Our view of information is from the perspective of social communica-tion sciences and the media. This view is intended to show the essential, desirable characteristics of information, important for media communication. Our analyzes are intended to signal some aspects of information theory, thus showing selected elements of the semantic-pragmatic platform for understanding and describing information. In our analyzes, we refer to the rich literature of Carl Friedrich von Weizsäcker, in order to draw theoretical and practical conclusions synthesizing by analyzing the content of his texts. Our analyzes are not only an attempt to theoretical description of the specifics and functionality of information, but are intended to provide valuable tips for increasing the informativeness of information in the processes of social communication.

Logistic architecture as new methodological and theoretical construct

The primary discussion of spatial organization that includes the analysis of the impact of logistics processes on flexibility, the transformability of spatial solutions and the transparency of space, has not been able to provide the theoretical and methodological interpretation of their spatio-temporal flow. This paper will point out the modalities of ?logistic architecture? production that break the design process tradition, as it turned out as unable to support creativity-based modes of reception of architectural ideas. The introduction of the ?logistic architecture? concept announces a new methodological and theoretical approach to the spatial syntheses of different processes in a building, aimed at achieving optimal spatio-temporal conditioning by the logistics system in relation to the use of creative strategy, as a part of the urban renovation. As my research field, this research observed the comparative flow of produced vehicles from the factory end line to the multi-story parking structures within two factories: Fiat Factory in Kragujevac, Serbia and Volkswagen Transparent Factory in Dresden, Germany.

Zebrafish forebrain and temporal conditioning

The rise of zebrafish as a neuroscience research model organism, in conjunction with recent progress in single-cell resolution whole-brain imaging of larval zebrafish, opens a new window of opportunity for research on interval timing. In this article, we review zebrafish neuroanatomy and neuromodulatory systems, with particular focus on identifying homologies between the zebrafish forebrain and the mammalian forebrain. The neuroanatomical and neurochemical basis of interval timing is summarized with emphasis on the potential of using zebrafish to reveal the neural circuits for interval timing. The behavioural repertoire of larval zebrafish is reviewed and we demonstrate that larval zebrafish are capable of expecting a stimulus at a precise time point with minimal training. In conclusion, we propose that interval timing research using zebrafish and whole-brain calcium imaging at single-cell resolution will contribute to our understanding of how timing and time perception originate in the vertebrate brain from the level of single cells to circuits.