Disturbed Balance of Inhibitory Signaling Links Hearing Loss and Cognition

Neuronal hyperexcitability in the central auditory pathway linked to reduced inhibitory activity is associated with numerous forms of hearing loss, including noise damage, age-dependent hearing loss, and deafness, as well as tinnitus or auditory processing deficits in autism spectrum disorder (ASD). In most cases, the reduced central inhibitory activity and the accompanying hyperexcitability are interpreted as an active compensatory response to the absence of synaptic activity, linked to increased central neural gain control (increased output activity relative to reduced input). We here suggest that hyperexcitability also could be related to an immaturity or impairment of tonic inhibitory strength that typically develops in an activity-dependent process in the ascending auditory pathway with auditory experience. In these cases, high-SR auditory nerve fibers, which are critical for the shortest latencies and lowest sound thresholds, may have either not matured (possibly in congenital deafness or autism) or are dysfunctional (possibly after sudden, stressful auditory trauma or age-dependent hearing loss linked with cognitive decline). Fast auditory processing deficits can occur despite maintained basal hearing. In that case, tonic inhibitory strength is reduced in ascending auditory nuclei, and fast inhibitory parvalbumin positive interneuron (PV-IN) dendrites are diminished in auditory and frontal brain regions. This leads to deficits in central neural gain control linked to hippocampal LTP/LTD deficiencies, cognitive deficits, and unbalanced extra-hypothalamic stress control. Under these conditions, a diminished inhibitory strength may weaken local neuronal coupling to homeostatic vascular responses required for the metabolic support of auditory adjustment processes. We emphasize the need to distinguish these two states of excitatory/inhibitory imbalance in hearing disorders: (i) Under conditions of preserved fast auditory processing and sustained tonic inhibitory strength, an excitatory/inhibitory imbalance following auditory deprivation can maintain precise hearing through a memory linked, transient disinhibition that leads to enhanced spiking fidelity (central neural gain⇑) (ii) Under conditions of critically diminished fast auditory processing and reduced tonic inhibitory strength, hyperexcitability can be part of an increased synchronization over a broader frequency range, linked to reduced spiking reliability (central neural gain⇓). This latter stage mutually reinforces diminished metabolic support for auditory adjustment processes, increasing the risks for canonical dementia syndromes.

The Role of Family Counseling in Overcoming Juvenile Delinquency

Juvenile delinquency is one of the deviant behaviors that requires special attention and good understanding and proper handling of the resolution process because it is an important factor for the success of adolescents in the next life, considering that the teenage transition period is the most decisive period. There are several roles that parents can do in overcoming juvenile delinquency, including the process of fostering and guidance carried out by the family. Parents try to create a harmonious, communicative and comfortable family for adolescents and help adolescents in their social and adjustment processes. Family counseling is a training process that is focused on the client's parents as the most influential person in determining the system in the family. This is done not to change the personality or character of the family members involved but to change the family through changing the behavior of the parents. If the behavior of the parents changes, it will affect the members in the family.

Self-initiated expatriate adjustment: South Korean workers in Vietnam

PurposeThe purpose of this study is to identify how young South Korean self-initiated expatriates (SIEs) have adjusted to their work and to verify the role of workplace learning activities as work adjustment processes in the relationship between work adjustment resources and outcomes.Design/methodology/approachThe study adopted a mixed-method approach, beginning with a qualitative study, followed by a quantitative study.FindingsThe main findings of the qualitative study indicated two types of SIE personal characteristics (ability to embrace cultural differences and entrepreneurship), their participation in training programs and that a supportive work environment which facilitates their work adjustment. Workplace learning, which led to role clarification within their organizations, is also critical for adjustment. Based on these findings, the quantitative research study examined the effects of personal and contextual factors on workplace learning and adjustment (n = 120). The quantitative part of the study found cultural intelligence (CQ), entrepreneurship, training programs and supportive environments were positively related to sociocultural adjustment through the work adjustment process.Research limitations/implicationsAs work adjustment is an important predictor of increased sociocultural adjustment among SIEs, organizations should build learning-supportive climates to promote workplace learning and seek people with appropriate characteristics for expatriation. Further studies should expand participant sample sizes to represent a wider population of SIEs.Originality/valueExtant literature on SIEs mainly explored their performance and management. This study explores their adjustment processes through the perspective of workplace learning.

THE DATABASE FOR MULTIFACTORIAL UAV ACCURACY ASSESSMENTS

Due to the increasing range of work carried out with UAV in recent years, the importance of final product accuracy appreciates. However, obtaining survey-grade accuracy requires to perform bundle adjustment processes that could be affected by multiple factors like unstable camera calibration, a correlation between interior and exterior orientation, insufficient georeferenced information, and software settings. During the project, multi-variant flight over the test field was conducted. The flights were performed with a fixed-wing airframe equipped with PPK receiver on-board. Based on the conducted flights, the database for multifactorial data sets has been prepared. The database containing hundreds of independent adjustment variants which differ as follows: georeferencing method, flight configuration, additional camera calibration corrections, tie points filtering, and a priori accuracy settings. The database allowed to investigate the separate influence of each factor on the final results using ANOVA statistical models.

THE TEST FIELD FOR UAV ACCURACY ASSESSMENTS

<p><strong>Abstract.</strong> Nowadays UAV photogrammetry becomes a common method for mapping and surveying. At the same time due to the increasing range of work carried out with UAV, the importance of final product accuracy increases. However to obtain survey-grade accuracy it is necessary to perform bundle adjustment processes that could be affected by multiple factors like unstable camera calibration, correlation between interior and exterior orientation and insufficient georeference information. One of the aims of the project was to prepare the terrestrial test field, which helps to obtain optimal decorrelation and allows to objectively assess the accuracy of the bundle adjustment in UAV application. During the project, two multi-variant flights over the test field were conducted. The flights were performed with a fixed-wing airframe equipped with PPK receiver on-board. Based on the conducted flights, many data sets have been prepared, which differ as follows: types of cameras, GSD, flight direction and georeferenced method.</p>

Cadet-Branch Matching in a Kelso-Crawford Economy

Sönmez (2013) and Sönmez and Switzer (2013) used matching theory with unilaterally substitutable priorities to propose mechanisms to match cadets to military branches. This paper shows that, alternatively, the Sönmez and Sönmez–Switzer mechanisms can be constructed as descending salary adjustment processes in Kelso-Crawford (1982) economies in which cadets are (grossly) substitutable. The lengths of service contracts serve as (inverse) salaries. The underlying substitutability explains the unilateral substitutability of the priorities utilized by Sönmez and Sönmez-Switzer. (JEL C78, D82, D86, J31, J45)