The biochemic system of medicine, also known as the inorganic cell salt therapy, pioneered by Dr. Wilhelm Heinrich Schuessler, following the footsteps of Dr. Samuel Hahnemann, is the oldest form of nutraceutical therapy approved and recognized by the World Health Organization as one of the complementary therapies. The chapter presents the fundamental ideology and concepts that underlies the promising system of biochemic medicine as concisely, simply, and to-the-point as possible. The chapter begins with a brief introduction to biochemic system, nutrition science, and concepts of nutraceuticals, followed by a brief history and literature review. It covers biochemic system of medicine and its relevant concepts before closing the chapter with a conclusion.