This chapter defines the behavioral markers that are included in a pattern-focused case conceptualization. Pattern-focused case conceptualization is a therapeutic strategy that can help clinicians conceptualize client issues, tailoring highly effective treatment, as well as guide them through moment-to-moment decisions made during a session. The chapter reviews the following behavioral markers that can be incorporated into both brief case conceptualizations and full-scale case conceptualizations: pattern, presentation, precipitant, predisposition, protective factors, perpetuants, personality–culture, plan, and predictive factors. The chapter defines each behavioral marker and also provides examples of each. Then, it reviews case conceptualization-informed assessment and also includes a detailed assessment that clinicians can use to inform their clinical evaluation.