transcranial duplex sonography
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2021 ◽  
Vol 20 (7) ◽  
pp. 2768
Author(s):  
A. B. Berdalin ◽  
A. Yu. Vishnyakova ◽  
I. L. Gubsky ◽  
D. A. Golovin ◽  
V. G. Lelyuk

Aim. To assess the state of intra- and extracranial arteries, white matter and cerebral cortex in asymptomatic hypertensive (HTN) patients according to multimodal examination.Material and methods. The study included data from 147 asymptomatic individuals (without prior ischemic stroke) with an established HTN (n=43; 29,3%) and without it. All participants underwent extracranial duplex ultrasound, transcranial duplex sonography, detection of middle cerebral artery microembolism, and brain magnetic resonance imaging. We performed a statistical analysis of the data obtained, adjusted for age and body mass index.Results. In patients with HTN, atherosclerotic plaques were more often detected — 37,2 vs 14,4% on the right (p=0,027) and 41,9 vs 13,5% on the left (p=0,001). In these patients, intima-media abnormalities and common carotid artery narrowing were also more common. Regional temporal lobe atrophy (p=0,044 on the right and p=0,046 on the left), central atrophy (p=0,045), focal periventricular white matter abnormalities (p=0,004) were more pronounced in hypertensive patients. There was no association between HTN and the presence of cerebral microbleeds, as well as the Montreal Cognitive Assessment (MoCA) score.Conclusion. In asymptomatic hypertensive patients relative to those without HTN, with comparable body mass index and age, head arterial abnormalities are more pronounced, but this regards only large ones — the common carotid artery. In these patients, more pronounced white matter and cerebral cortex changes were revealed.



2021 ◽  
Author(s):  
Csilla Molnár ◽  
Judit Gál ◽  
Dorottya Szántó ◽  
László Fülöp ◽  
Andrea Szegedi ◽  
...  

Abstract Background: Takotsubo cardiomyopathy (TTC) is an important complication of subarachnoid hemorrhage (SAH), that may delay surgical or endovascular treatment and may influence patient outcome. This prospective follow-up study intended to collect data on the prevalence, severity, influencing factors and long-term outcome of TTC in patients suffering from non-traumatic SAH. Methods: Consecutive patients admitted with the diagnosis of non-traumatic SAH were included. Intitial assessment consisted of cranial CT, Hunt-Hess, Fisher and WFNS scoring, 12-lead ECG, transthoracic echocardiography (TTE), transcranial duplex sonography and collecting laboratory parameters (CK, CK-MB, cardiac troponin T, NT-proBNP and urine metanephrine and normetanephrine). Diagnosis of TTC was based on modified Mayo criteria. TTC patients were dichotomized to mild and severe forms. Follow-up of TTE, Glasgow Outcome Scale assessment, Barthel’s and Karnofsky scoring occurred on days 30 and 180.Results: One hundred thirty six patients were included. The incidence of TTC in the entire cohort was 28.7 %; of them, 20.6% and 8.1% were mild and severe, respectively. TTC was more frequent in females (30/39; 77%) than in males (9/39; 23%) and was more severe. The occurrence of TTC was related to mFisher scores and WFNS scores. Although the severity of TTC was related to mFisher score, Hunt-Hess score, WFNS score and GCS, multivariate analysis showed the strongest relationship with mFisher scores. Ejection fraction differences between groups were present on day 30, but disappeared by day 180, whereas wall motion score index was still higher in the severe TTC group at day 180. By the end of the follow-up period (180 days), 70 (74.5%) patients survived in the non-TTC, 22 (81.5%) in the mild TTC and 3 (27%) in the severe TTC group (n = 11) (p = 0.002). At day 180, GOS, Barthel, and Karnofsky outcome scores were higher in patients in the control (non-TTC) and the mild TTC groups than in the severe TTC group. Conclusions: Takotsubo cardiomyopathy is a frequent finding in patients with SAH, and severe TTC may be present in 8% of SAH cases. The severity of TTC may be an independent predictor of mortality and outcome at 6 months after disease onset. Therefore, a regular follow-up of ECG and TTE abnormalities is warranted in patients with subrachnoid hemorrhage for early detection of TTC. Trial registration: The study was registered at the Clinical Trials Register under the registration number of NCT02659878 (date of registration: January 21, 2016)



2020 ◽  
Author(s):  
Meng Zhu ◽  
Jiahui Zhang ◽  
Shuang Mu ◽  
Wei Liu ◽  
Wenshuai Deng ◽  
...  

Abstract Objective Decompressive craniectomy (DC) is widely used to treat intracranial hypertension following severe head injury. However, impairments of cerebrospinal fluid (CSF) hydrodynamics such as hydrocephalus and subdural effusion are common complications that occur after DC. Therefore, monitoring of intracranial pressure is a staple of neurocritical care post-DC. The aim of this study was to assess the usefulness of transcranial duplex sonography (TDS) for serial monitoring and management of CSF disorders after DC. Methods A total of 100 patients who underwent DC between June 2016 and May 2019 were recruited for the study. TDS examinations were performed between 1 day and 1-year post-DC. TDS was mainly used for monitoring changes in ventricle size and morphology, and also to monitor intraventricular hemorrhage (IVH), hydrocephalus, intracranial hygromas, and ventricle changes during CSF release procedures. Results A total of 456 TDS examinations were performed on patients after DC. Of these, 402 were performed in the neuro-ICU. Two patients had IVH and underwent TDS-guided external ventricular drainage (EVD). Twenty-nine patients were diagnosed with hydrocephalus. The results of TDS were consistent with those of cranial computed tomography (CCT). Three cases of ventriculoperitoneal shunt and 1 case of lumbar peritoneal shunt underwent valve pressure reset according to TDS, in order to obtain satisfactory ventricle size. TDS was used to monitor ventricle changes and control drainage volume during CSF release procedures, including 2 EVD, 6 external lumbar drainage, and 10 lumbar punctures. Eighteen patients were detected with single or multiple intracranial effusions, including 16 subdural hygromas, 5 longitudinal fissure hygromas, and 6 brain cysts. Conclusions TDS can efficiently help monitor changes in ventricle size and morphology and intracranial effusions. Due to its noninvasive nature, suitability for bedside application, real-time and inexpensiveness, TDS can significantly replace CCT and become part of the patient's daily inspection work after DC.



2020 ◽  
Vol 46 (8) ◽  
pp. 1889-1895
Author(s):  
Leon Alexander Danyel ◽  
Sara Hadzibegovic ◽  
Jose Manuel Valdueza ◽  
Anna Tietze ◽  
Simon Fuchs ◽  
...  


2020 ◽  
Vol 24 (1) ◽  
pp. 85-95
Author(s):  
L. T. Khamidova ◽  
N. V. Rybalko ◽  
V. V. Krylov ◽  
S. S. Petrikov ◽  
A. V. Klimov




Stroke ◽  
2018 ◽  
Vol 49 (11) ◽  
pp. 2780-2782 ◽  
Author(s):  
Markus Kneihsl ◽  
Kurt Niederkorn ◽  
Hannes Deutschmann ◽  
Christian Enzinger ◽  
Birgit Poltrum ◽  
...  




2017 ◽  
Vol 38 (8) ◽  
pp. 1543-1549 ◽  
Author(s):  
P. Camps-Renom ◽  
J. Méndez ◽  
E. Granell ◽  
F. Casoni ◽  
L. Prats-Sánchez ◽  
...  




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