Background/Aim. Multiple sclerosis (MS) is a chronic autoimmune inflammatory
disorder of the unknown origin leading to multifocal demyelization, axonal
damage and the loss of the nervous tissue in various parts of the central
nervous system. Most MS patients have decreased functionality of the bladder
leading to various dysuria disorders during the course of the illness.
However, in 2% of the cases dysuric problems are the first symptoms of the
disease. Urodynamic testing could help to diagnose functional disorders of
the lower urinary tract, which might not be otherwise possible by performing
the standard invasive procedures or noninvasive scans, such us ultrasound,
computed tomography or functional magnetic resonance imaging (fMRI). Methods.
Urodynamic testing - cystometry with electromyographic (EMG) potentials from
the external anal sphincter (EAS), was performed in 34 patients (25 female
and 9 male patients). Those patients fulfilled Mc Donald?s multiple sclerosis
criteria. The urodynamic values were compared to neurological signs and the
present disease symptoms. Results. The MS patients with (27) and without (7)
miction problems were tested. Detrusor hyperreflexia is the most common
finding, present in 58.8% of the cases. More than a half of the patients have
detrusor sphincter dissynergia. Conclusions. Urodynamic testing helps us to
determine neurological disorders characteristics and to prepare an
appropriate treatment plan. During the course of the disease different
urodynamic disfunctions may occur as well as changes in the urinating
functionality. The rationale for urodynamic testing in patients suffering
from MS before any other treatment procedure is to confirm the diagnosis of
dysuric disorders and to secure appropriate treatment.