The fluctuating décor of youth identity in Post-Colonial South Africa

This paper aims to discuss South African youths living in democratic South Africa, it will look critically on the youth definition and, highlight a brief outlook on the youth and society in the African context. It will look African youths as centre of social interfaces and revolution, due to their role in in different structures, culture, sacraments, and social movement. Moreover, it will examine the Born Free generation is an attempt to trigger a dialogue necessary to challenge youth identity crises, youth disparities in education, housing, health care and employment opportunities. Lastly, this paper will look closer on conditions facing young Blacks in today’s South Africa in relation to identity crisis, challenges and opportunities of today’s youths.

Institutional Traps for the Development of a Corporation's Creative Potential

The process of free formation and development of the creative potential of corporations in the context of the expansion of the digital economy is associated with the emergence of specific obstacles, which in economic theory are called development traps. Verifying this position, the article analyzes the institutional pitfalls of the development of creative potential caused by modern transformations. The concept of the institutional trap, first formulated in the works of P. David and D. North, and further developed in the works of A. Auzan, E. Balatsky, G. Kleiner, V. Polterovich seems to have been known and developed for a long time, but this is the trap of the trap itself. Despite all the banality and familiarity of the category of institutional trap in the Russian economy associated with the establishment of an inefficient norm, in recent years it has again attracted the attention of participants in various areas of scientific research, since it has significant hidden opportunities in the study of the formation and development of the creative potential of the corporation in the era of modern transformations. The creative potential, represented as a powerful creative force, endowed with special intellectual capital and competencies, is actively involved in accelerating transformations, the results of which are not always predictable, expected, accompanied by certain obligations and very unpredictable inertial results. Effective implementation of the creative potential of the corporation and its intellectual core involves expanding the opportunities for free generation of the creative potential of the corporation and overcoming specific obstacles to this formation associated with the processes of large-scale economic transformations, network development, corporate standardization and nationalization. We present the creative potential of the corporation as a kind of intellectual core, consisting of professional intellectuals who are able to generate new business development ideas and offer capital combinations of resources that do not fit into the standards, claiming to be the main ones. Through the prism of the pitfalls of developing the creative potential of the corporation, the author examines the main problems and contradictions of the transformations taking place in the Russian economy at the present stage. The research was conducted using the resources of the system economy, creative economy, knowledge economy, institutional economy, dialectics method, comparative analysis method, and empirical method.

HMPA-Free Generation of Trialkylsilyllithium Reagents and Its Applications to the Synthesis of Silylboronic Esters

Trialkylsilyllithium species have turned out to be facilely generated by treating hexaalkyldisilanes with methyllithium in the presence of tris(N,N-tetramethylene)phosphoric triamide (TPPA) as an activator, which can be trapped by boron electrophiles to afford silylboronic esters including long-awaited Me3Si–B(pin).

Photomodulation of lymphatic delivery of liposomes to the brain bypassing the blood-brain barrier: new perspectives for glioma therapy

The blood-brain barrier (BBB) has a significant contribution to the protection of the central nervous system (CNS). However, it also limits the brain drug delivery and thereby complicates the treatment of CNS diseases. The development of safe methods for an effective delivery of medications and nanocarriers to the brain can be a revolutionary step in the overcoming this limitation. Here, we report the unique properties of the lymphatic system to deliver tracers and liposomes to the brain meninges, brain tissues, and glioma in rats. Using a quantum-dot-based 1267 nm laser (for photosensitizer-free generation of singlet oxygen), we clearly demonstrate photostimulation of lymphatic delivery of liposomes to glioma as well as lymphatic clearance of liposomes from the brain. These pilot findings open promising perspectives for photomodulation of lymphatic delivery of drugs and nanocarriers to the brain pathology bypassing the BBB. The lymphatic “smart” delivery of liposomes with antitumor drugs in the new brain tumor branches might be a breakthrough strategy for the therapy of gliomas.