Unveiling Economic Co-Benefits of Virtual Water Trades: An Empirical Analysis on China’s JingJinJi Megalopolis

The development of metropolitan cities inevitably relies on natural resources beyond their boundary through trade of materials and products, particularly within the same urban agglomeration. Meanwhile trade facilitates the optimization of resource allocations under scarcity, among cities and sectors, and therefore generates economic gains. This study constructs an economic evaluation model combining a Multi-Regional Input-Output model and a Data Envelopment Analysis (DEA) to quantify the economic impacts of virtual water trades among the 13 cities in the JingJinJi region (China national capital area), one of the most water-scarce regions in China. We found that the total virtual water trade among the 13 cities amounted to 927 million m3 in 2012, among which agricultural sectors contributed 90% while the industrial sector and service sector together made up the remaining 10%. While Beijing and Tianjin are the main virtual water importers, importing respectively 300.48 and 226.92 million m3 in 2012, Shijiazhuang was the largest virtual water exporter, exporting 173.29 million m3 virtual water in the same year. Due to their more advanced economic conditions, Beijing and Tianjin also have the highest shadow prices of water, at respectively 912.21 and 831.86 CNY per m3, compared to a range of 79.31 to 263.03 CNY per m3 in cities in Hebei. Virtual water flows from cities in Hebei to Beijing and Tianjin thus generate economic gains. It is estimated that virtual water trades in the JingJinJi region have generated a net economic gain of 403.62 billion CNY in 2012, particularly owing to trades of agricultural products from Shijiazhuang to Beijing and Tianjin.

Stakeholder engagement in economic evaluation: Protocol for using the nominal group technique to elicit patient, healthcare provider, and health system stakeholder input in the development of an early economic evaluation model of chimeric antigen receptor T-cell therapy

IntroductionChimeric antigen receptor T-cell (CAR-T) therapy is a class of immunotherapy. An economic evaluation conducted at an early stage of development of CAR-T therapy for treatment of adult relapsed or refractory acute lymphoblastic leukaemia could provide insight into factors contributing to the cost of treatment, the potential clinical benefits, and what the health system can afford. Traditionally, stakeholders are engaged in certain parts of health technology assessment processes, such as in the identification and selection of technologies, formulation of recommendations, and implementation of recommendations; however, little is known about processes for stakeholder engagement during the conduct of the assessment. This is especially the case for economic evaluations. Stakeholders, such as clinicians, policy-makers, patients, and their support networks, have insight into factors that can enhance the validity of an economic evaluation model. This research outlines a specific methodology for stakeholder engagement and represents an avenue to enhance health economic evaluations and support the use of these models to inform decision making for resource allocation. This protocol may inform a tailored framework for stakeholder engagement processes in future economic evaluation model development.Methods and analysisWe will involve clinicians, healthcare researchers, payers, and policy-makers, as well as patients and their support networks in the conduct and verification of an early economic evaluation of a novel health technology to incorporate stakeholder-generated knowledge. Three stakeholder-specific focus groups will be conducted using an online adaptation of the nominal group technique to elicit considerations from each. This study will use CAR-T therapy for adults with relapsed or refractory B-cell acute lymphoblastic leukaemia as a basis for investigating broader stakeholder engagement processes.Ethics and disseminationThis study received ethics approval from the Ottawa Hospital Research Institute Research Ethics Board (REB 20200320-01HT) and the results will be shared via conference presentations, peer-reviewed publications, and ongoing stakeholder engagement.

Economic Analysis and Evaluation of Energy-efficient Renovation of Existing Buildings Based on the Whole Life Cycle

There has long been a lack of understanding of the costs and benefits of energy-efficient renovation of existing buildings, which discourages the participation of stakeholders. This paper studied the energy-saving renovation of existing buildings, analyzed the incremental cost and incremental benefit based on the whole life cycle, and constructed the economic evaluation model of energy-saving renovation of existing buildings to provide a scientific theoretical basis for the economic evaluation of the energy-saving renovation of existing buildings and provide references for the decision-making of stakeholders, and promote the energy-saving renovation of buildings from an economic point of view.